Browsing Institutt for medisinske basalfag by Title

Now showing items 33-52 of 3159

  • A correction for sample overlap in genome-wide association studies in a polygenic pleiotropy-informed framework 
    LeBlanc, Marissa; Zuber, Verena; Thompson, Wesley K; Andreassen, Ole A; Frigessi, Arnoldo; Andreassen, Bettina K (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
    Background There is considerable evidence that many complex traits have a partially shared genetic basis, termed pleiotropy. It is therefore useful to consider integrating genome-wide association study ...
  • A cross-sectional prospective study of seclusion, restraint and involuntary medication in acute psychiatric wards: patient, staff and ward characteristics 
    Husum, Tonje L; Bjørngaard, Johan H; Finset, Arnstein; Ruud, Torleif (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2010)
    Background Previous research on mental health care has shown considerable differences in use of seclusion, restraint and involuntary medication among different wards and geographical areas. This study ...
  • A day-by-day investigation of changes in criminal convictions before and after entering and leaving opioid maintenance treatment: a national cohort study 
    Bukten, Anne; Røislien, Jo; Skurtveit, Svetlana; Waal, Helge; Gossop, Michael; Clausen, Thomas (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2013)
  • A diet change from dry food to beef induces reversible changes on the faecal microbiota in healthy, adult client-owned dogs 
    Herstad, Kristin M V; Gajardo, Karina; Bakke, Anne M; Moe, Lars; Ludvigsen, Jane; Rudi, Knut; Rud, Ida; Sekelja, Monika; Skancke, Ellen (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
    Background Diet has a major influence on the composition of the gut microbiota, whose importance for gut health and overall well-being is increasingly recognized. Knowledge is limited regarding health ...
  • A few more minutes make a difference? The relationship between content and length of GP consultations 
    Gude, Tore; Vaglum, Per Jørgen Wiggen; Anvik, Tor; Baerheim, Anders; Grimstad, Hilde (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2013)
    Objectives. To investigate the relationship between the length of a medical consultation in a general practice setting and the biopsychosocial information obtained by the physician, and to explore the characteristics of ...
  • A framework to assess the quality and impact of bioinformatics training across ELIXIR 
    Gurwitz, Kim T.; Gaur, Prakash Singh; Bellis, Louisa J.; Larcombe, Lee; Alloza, Eva; Balint, Balint Laszlo; Botzki, Alexander; Dimec, Jure; del Angel, Victoria Dominguez; Fernandes, Pedro L.; Korpelainen, Eija; Krause, Roland; Kuzak, Mateusz; Le Pera, Loredana; Leskošek, Brane; Lindvall, Jessica M.; Marek, Diana; Martinez, Paula A.; Muyldermans, Tuur; Nygård, Ståle; Palagi, Patricia M.; Peterson, Hedi; Psomopoulos, Fotis; Spiwok, Vojtech; van Gelder, Celia W.G.; Via, Allegra; Vidak, Marko; Wibberg, Daniel; Morgan, Sarah L.; Rustici, Gabriella (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
    ELIXIR is a pan-European intergovernmental organisation for life science that aims to coordinate bioinformatics resources in a single infrastructure across Europe; bioinformatics training is central to its strategy, which ...
  • A guide to the BRAIN Initiative Cell Census Network data ecosystem 
    Hawrylycz, Michael; Martone, Maryann E.; Ascoli, Giorgio A.; Bjaalie, Jan G.; Dong, Hong-Wei; Ghosh, Satrajit S.; Gillis, Jesse; Hertzano, Ronna; Haynor, David R.; Hof, Patrick R.; Kim, Yongsoo; Lein, Ed; Liu, Yufeng; Miller, Jeremy A.; Mitra, Partha P.; Mukamel, Eran; Ng, Lydia; Osumi-Sutherland, David; Peng, Hanchuan; Ray, Patrick L.; Sanchez, Raymond; Regev, Aviv; Ropelewski, Alex; Scheuermann, Richard H.; Tan, Shawn Zheng Kai; Thompson, Carol L.; Tickle, Timothy; Tilgner, Hagen; Varghese, Merina; Wester, Brock; White, Owen; Zeng, Hongkui; Aevermann, Brian; Allemang, David; Ament, Seth; Athey, Thomas L.; Baker, Cody; Baker, Katherine S.; Baker, Pamela M.; Bandrowski, Anita; Banerjee, Samik; Bishwakarma, Prajal; Carr, Ambrose; Chen, Min; Choudhury, Roni; Cool, Jonah; Creasy, Heather; D'Orazi, Florence; Degatano, Kylee; Dichter, Benjamin; Ding, Song-Lin; Dolbeare, Tim; Ecker, Joseph R.; Fang, Rongxin; Fillion-Robin, Jean-Christophe; Fliss, Timothy P.; Gee, James; Gillespie, Tom; Gouwens, Nathan; Zhang, Guo-Qiang; Halchenko, Yaroslav O.; Harris, Nomi L.; Herb, Brian R.; Hintiryan, Houri; Hood, Gregory; Horvath, Sam; Huo, Bingxing; Jarecka, Dorota; Jiang, Shengdian; Khajouei, Farzaneh; Kiernan, Elizabeth A.; Kir, Huseyin; Kruse, Lauren; Lee, Changkyu; Lelieveldt, Boudewijn; Li, Yang; Liu, Hanqing; Liu, Lijuan; Markuhar, Anup; Mathews, James; Mathews, Kaylee L.; Mezias, Chris; Miller, Michael I.; Mollenkopf, Tyler; Mufti, Shoaib; Mungall, Christopher J.; Orvis, Joshua; Puchades, Maja; Qu, Lei; Receveur, Joseph P.; Ren, Bing; Sjoquist, Nathan; Staats, Brian; Tward, Daniel; van Velthoven, Cindy T.J.; Wang, Quanxin; Xie, Fangming; Xu, Hua; Yao, Zizhen; Yun, Zhixi; Zhang, Yun Renee; Zheng, W. Jim; Zingg, Brian (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
    Characterizing cellular diversity at different levels of biological organization and across data modalities is a prerequisite to understanding the function of cell types in the brain. Classification of neurons is also ...
  • A high prevalence of bla OXA-48 in Klebsiella (Raoultella) ornithinolytica and related species in hospital wastewater in South West England 
    Gibbon, Marjorie J.; Couto, Natacha; David, Sophia; Barden, Ruth; Standerwick, Richard; Jagadeesan, Kishore Kumar; Birkwood, Hollie; Dulyayangkul, Punyawee; Avison, Matthew B.; Kannan, Andrew; Kibbey, Dan; Craft, Tim; Habib, Samia; Thorpe, Harry Arthur Frank Wright; Corander, Jukka; Kasprzyk-Hordern, Barbara; Feil, Edward J. (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
    Klebsiella species occupy a wide range of environmental and animal niches, and occasionally cause opportunistic infections that are resistant to multiple antibiotics. In particular, Klebsiella pneumoniae (Kpne) has gained ...
  • A high-throughput multiplexing and selection strategy to complete bacterial genomes 
    Alonso, Sergio Arredondo; Pöntinen, Anna K.; Cleon, Francois Pierre Alexandre; Gladstone, Rebecca Ashley; Schürch, Anita C.; Johnsen, Pål Jarle; Samuelsen, Ørjan; Corander, Jukka (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
    Abstract Background Bacterial whole-genome sequencing based on short-read technologies often results in a draft assembly formed by contiguous sequences. The introduction of long-read ...
  • A human iPSC-astroglia neurodevelopmental model reveals divergent transcriptomic patterns in schizophrenia 
    Szabo, Attila; Akkouh, Ibrahim Ahmed; Vandenberghe, Matthieu; Osete, Jordi Requena; Hughes, Timothy; Heine, Vivi M.; Smeland, Olav Bjerkehagen; Glover, Joel Clinton; Andreassen, Ole; Djurovic, Srdjan (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
    Abstract While neurodevelopmental abnormalities have been associated with schizophrenia (SCZ), the role of astroglia in disease pathophysiology remains poorly understood. In the present study, we used a human induced ...
  • A hybrid landmark Aalen-Johansen estimator for transition probabilities in partially non-Markov multi-state models 
    Maltzahn, Niklas; Hoff, Rune; Aalen, Odd O.; Mehlum, Ingrid S.; Putter, Hein; Gran, Jon Michael (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
    Multi-state models are increasingly being used to model complex epidemiological and clinical outcomes over time. It is common to assume that the models are Markov, but the assumption can often be unrealistic. The Markov ...
  • A hyper-dynamic nature of bivalent promoter states underlies coordinated developmental gene expression modules 
    Shah, Akshay; Oldenburg, Anja; Collas, Philippe (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)
    Background Chromatin remodeling is crucial for proper programing of developmental gene expression. Recent work provides a dynamic view of post-translational histone modifications during differentiation; ...
  • A Key Characteristic of Sex Differences in the Developing Brain: Greater Variability in Brain Structure of Boys than Girls 
    Wierenga, Lara M.; Sexton, Joseph; Laake, Petter; Giedd, Jay N.; Tamnes, Christian Krog (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2018)
    In many domains, including cognition and personality, greater variability is observed in males than in females in humans. However, little is known about how variability differences between sexes are represented in the ...
  • A large-scale genomic snapshot of Klebsiella spp. isolates in Northern Italy reveals limited transmission between clinical and non-clinical settings 
    Thorpe, Harry Arthur Frank Wright; Booton, Ross; Kallonen, Teemu; Gibbon, Marjorie J.; Couto, Natacha; Passet, Virginie; López-Fernández, Sebastián; Rodrigues, Carla; Matthews, Louise; Mitchell, Sonia; Reeve, Richard; David, Sophia; Merla, Cristina; Corbella, Marta; Ferrari, Carolina; Comandatore, Francesco; Marone, Piero; Brisse, Sylvain; Sassera, Davide; Corander, Jukka; Feil, Edward J. (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
    Abstract The Klebsiella group, found in humans, livestock, plants, soil, water and wild animals, is genetically and ecologically diverse. Many species are opportunistic pathogens and can harbour diverse classes of antimicrobial ...
  • A lean additive frailty model: With an application to clustering of melanoma in Norwegian families 
    Brathovde, Mari; Moger, Tron Anders; Aalen, Odd O.; Grotmol, Tom; Veierød, Marit Bragelien; Valberg, Morten (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
    Additive frailty models are used to model correlated survival data. However, the complexity of the models increases with cluster size to the extent that practical usage becomes increasingly challenging. We present a ...
  • A loss-of-function mutation in human Oxidation Resistance 1 disrupts the spatial–temporal regulation of histone arginine methylation in neurodevelopment 
    Lin, Xiaolin; Wang, Wei; Yang, Mingyi; Damseh, Nadirah; de Sousa, Mirta M. L.; Jacob, Fadi; Lång, Anna; Kristiansen, Elise; Pannone, Marco; Kissova, Miroslava; Almaas, Runar; Kuśnierczyk, Anna; Siller, Richard; Shahrour, Maher; Al-Ashhab, Motee; Abu-Libdeh, Bassam; Tang, Wannan; Slupphaug, Geir; Elpeleg, Orly; Bøe, Stig O.; Eide, Lars; Sullivan, Gareth J.; Rinholm, Johanne E.; Song, Hongjun; Ming, Guo-li; van Loon, Barbara; Edvardson, Simon; Ye, Jing; Bjørås, Magnar (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
    Background Oxidation Resistance 1 (OXR1) gene is a highly conserved gene of the TLDc domain-containing family. OXR1 is involved in fundamental biological and cellular processes, including DNA damage response, ...
  • A low FODMAP diet reduces symptoms in treated celiac patients with ongoing symptoms–A randomized controlled trial 
    van Megen, Frida; Skodje, Gry Irene; Lergenmuller, Simon; Zühlke, Stephanie; Aabakken, Lars; Veierød, Marit Bragelien; Henriksen, Christine; Lundin, Knut (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
    Background & Aims A gluten-free diet usually leads to mucosal remission in celiac disease, but persistent symptoms are common. A low fermentable oligo-, di-, monosaccharides and polyols (FODMAP) diet is an established ...
  • A Massive Extradural Hematoma in Sickle Cell Disease and the Importance of Rapid Neuroimaging 
    Iversen, Per Ole; Jacob, Mboka; Makame, Jamila; Abisay, Mclean; Yonazi, Mbonea; Schuh, Anna; Makani, Julie (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
    Sickle cell disease (SCD) is an inherited hemoglobinopathy leading to several serious organ complications and early death. It is mostly found in equatorial countries like Tanzania. Extradural hematoma (EDH) is a rare, but ...
  • A maternal meal affects clinical Doppler parameters in the fetal middle cerebral artery 
    Opheim, Gun Lisbeth; Zucknick, Manuela; Henriksen, Tore; Haugen, Guttorm (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
    Introduction Middle cerebral artery (MCA) and umbilical artery (UA) Doppler blood flow pulsatility indices (PIs) and MCA peak systolic velocity (PSV) are essential variables for clinically evaluating fetal well-being. ...
  • A method for differentiating human induced pluripotent stem cells toward functional cardiomyocytes in 96-well microplates 
    Balafkan, Novin; Mostafavi, Sepideh; Schubert, Manja; Siller, Richard; Liang, Xiao; Sullivan, Gareth; Bindoff, Laurence (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
    Abstract The capacity of pluripotent stem cells both for self-renewal and to differentiate into any cell type have made them a powerful tool for studying human disease. Protocols for efficient differentiation towards ...