Now showing items 2771-2790 of 3159

  • Gilmour, Brian Christopher; Gudmundsrud, Ruben; Frank, Johannes; Hov, Amund; Hindkjær Lautrup, Sofie; Aman, Yahyah; Røsjø, Helge; Brenner, Charles; Ziegler, Mathias; Tysnes, Ole-Bjørn; Tzoulis, Charalampos; Omland, Torbjørn; Søraas, Arne Vasli; Holmøy, Trygve; Bergersen, Linda Hildegard; Storm-Mathisen, Jon; Nilsen, Hilde; Fang, Evandro Fei (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2020)
    Nicotinamide adenine dinucleotide (NAD+) plays a fundamental role in life and health through the regulation of energy biogenesis, redox homeostasis, cell metabolism, and the arbitration of cell survival via linkages to ...
  • Joel, Mrinal; Mughal, Awais A; Grieg, Zanina; Murrell, Wayne; Palmero, Sheryl; Mikkelsen, Birthe; Fjerdingstad, Hege B; Sandberg, Cecilie J; Behnan, Jinan; Glover, Joel C; Langmoen, Iver A; Stangeland, Biljana (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)
    Background Glioblastomas are invasive therapy resistant brain tumors with extremely poor prognosis. The Glioma initiating cell (GIC) population contributes to therapeutic resistance and tumor recurrence. ...
  • Herhaus, Lina; Bhaskara, Ramachandra M; Lystad, Alf Håkon; Gestal-Mato, Uxia; Covarrubias-Pinto, Adriana; Bonn, Florian; Simonsen, Anne; Hummer, Gerhard; Dikic, Ivan (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
    Autophagy is a highly conserved catabolic process through which defective or otherwise harmful cellular components are targeted for degradation via the lysosomal route. Regulatory pathways, involving post‐translational ...
  • Amoriello, Roberta; Chernigovskaia, Mariia; Greiff, Victor; Carnasciali, Alberto; Massacesi, Luca; Barilaro, Alessandro; Repice, Anna Maria; Biagioli, Tiziana; Aldinucci, Alessandra; Muraro, Paolo A.; Laplaud, David-Axel; Lossius, Andreas; Ballerini, Clara (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
    Background T cells play a key role in the pathogenesis of multiple sclerosis (MS), a chronic, inflammatory, demyelinating disease of the central nervous system (CNS). Although several studies recently investigated the ...
  • Vitali, Veronica; Tiboldo, Giulia; Castellari, Elena; Meshkovska, Biljana (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2023)
    Objective: School-based fruit and vegetable provision programmes can improve children’s eating patterns and health by ensuring access to fruit and vegetables and providing nutrition education. However, the effectiveness ...
  • Yazdani, Mazyar; Fiskådal, Jørgen; Chen, Xiangjun; Utheim, Øygunn Aass; Ræder, Sten; Vitelli, Valeria; Utheim, Tor Paaske (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
    This study evaluated to what extent tear film break-up time (TFBUT) could discriminate pathological scores for other clinical tests and explore the associations between them. Dry eye patients (n = 2094) were examined for ...
  • Azqueta, Amaya; Muruzabal, Damian; Boutet-Robinet, Elisa; Milic, Mirta; Dusinska, Maria; Brunborg, Gunnar; Møller, Peter; Collins, Andrew R. (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2019)
    The comet assay (single cell gel electrophoresis) is widely used as a biomonitoring tool to assess DNA damage – strand breaks, as well as oxidised bases; it can also be adapted to measure DNA repair. It is based on the ...
  • Kaur, Namrita; de la Ballina, Laura R; Haukaas, Håvard Styrkestad; Torgersen, Maria Lyngaas; Radulovic, Maja; Munson, Michael J; Sabirsh, Alan; Stenmark, Harald Alfred; Simonsen, Anne Gjøen; Carlsson, Sven R; Lystad, Alf Håkon Lohsen (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
    Abstract Cells use noncanonical autophagy, also called conjugation of ATG8 to single membranes (CASM), to label damaged intracellular compartments with ubiquitin‐like ATG8 family proteins in order to signal danger caused ...
  • Klepp, Knut-Inge; Wind, Marianne; de Bourdeaudhuij, Ilse; Rodrigo, Carmen P; Due, Pernille; Bjelland, Mona; Brug, Johannes (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2007)
    Background Fruit and vegetable intake is low among European children and exposure to TV is negatively associated with the intake of fruit and vegetables. The aim of the present study was to explore exposure ...
  • Winje, Brita A; Røislien, Jo; Frøen, J F (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2012)
    Background Fetal movement counting has long been suggested as a screening tool to identify impaired placental function. However, quantitative limits for decreased fetal movement perform poorly for screening ...
  • Manueldas, Sophia; Benterud, Torkil; Rueegg, Corina Silvia; Garberg, Håvard Tetlie; Huun, Marianne Ullestad; Pankratov, Leonid; Atneosen-Åsegg, Monica; Solberg, Rønnaug; Escobar, Javier; Saugstad, Ola Didrik; Baumbusch, Lars Oliver (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
    Heart failure is associated with low cardiac output (CO) and low brain perfusion that imposes a significant risk for accelerated brain ageing and Alzheimer’s disease (AD) development. Although clinical heart failure can ...
  • Aasebø, Ida E. J.; Lepperød, Mikkel Elle; Stavrinou, Maria; Nøkkevangen, Sandra; Einevoll, Gaute; Hafting, Torkel; Fyhn, Marianne (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
    The activity pattern and temporal dynamics within and between neuron ensembles are essential features of information processing and believed to be profoundly affected by anesthesia. Much of our general understanding of ...
  • Gottschalk, Marthe Sørli; Eskild, Anne; Hofvind, Solveig; Gran, Jon Michael; Bjelland, Elisabeth Krefting (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
    Abstract STUDY QUESTION Have mean age at menarche or mean age at natural menopause changed from the 1939 birth cohort to the 1964 birth cohort? SUMMARY ...
  • Barder, Helene; Sundet, Kjetil Søren; Rund, Bjørn Rishovd; Evensen, Julie Horgen; Haahr, Ulrik; Hegelstad, Wenche; Joa, Inge; Johannessen, Jan Olav; Langeveld, Johannes H.; Larsen, Tor Ketil; Melle, Ingrid; Ilner, Stein E. Opjordsmoen; Røssberg, Jan Ivar; Simonsen, Erik; Vaglum, Per Jørgen Wiggen; McGlashan, Thomas; Friis, Svein (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2013)
    Objective: Neurocognitive impairment is commonly reported at onset of psychotic disorders. However, the long-term neurocognitive course remains largely uninvestigated in first episode psychosis (FEP) and the relationship ...
  • Tsuruda, Kaitlyn; Hofvind, Solveig; Akslen, Lars A.; Hoff, Solveig Roth; Veierød, Marit Bragelien (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
    Objectives: Women diagnosed with breast cancer are offered treatment and therapy based on tumor characteristics, including tumor diameter. There is scarce knowledge whether tumor diameter is accurately reported, or whether ...
  • Parr, Christine L; Veierød, Marit B; Laake, Petter; Lund, Eiliv; Hjartåker, Anette (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2006)
    Background The Norwegian Women and Cancer Study (NOWAC) is a national population-based cohort study with 102 443 women enrolled at age 30–70 y from 1991 to 1997. The present study was a methodological ...
  • Aune, Erlend; Røislien, Jo; Mathisen, Mariann; Thelle, Dag S; Erik Otterstad, Jan (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2011)
    Background Smokers have been shown to have lower mortality after acute coronary syndrome than non-smokers. This has been attributed to the younger age, lower co-morbidity, more aggressive treatment and lower ...
  • Sporbeck, Katharina; Haas, Maximilian L.; Pastor-Maldonado, Carmen J.; Schüssele, David S.; Hunter, Catherine; Takacs, Zsuzsanna; Diogo de Oliveira, Ana L.; Franz-Wachtel, Mirita; Charsou, Chara; Pfisterer, Simon G.; Gubas, Andrea; Haller, Patricia K.; Knorr, Roland L.; Kaulich, Manuel; Macek, Boris; Eskelinen, Eeva-Liisa; Simonsen, Anne Gjøen; Proikas-Cezanne, Tassula (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
    Abstract Human WIPI β-propellers function as PI3P effectors in autophagy, with WIPI4 and WIPI3 being able to link autophagy control by AMPK and TORC1 to the formation of autophagosomes. WIPI1, instead, assists WIPI2 in ...
  • Olsen, Petter Angell; Krauss, Stefan Johannes Karl (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
    HEK293 cells are one of the most widely used cell lines in research, and HEK293 cells are frequently used as an in vitro model for studying the WNT signaling pathway. The HEK293 cell line was originally established by ...