Browsing Institutt for medisinske basalfag by Title

Now showing items 2771-2790 of 3159

  • Targeting NAD+ in translational research to relieve diseases and conditions of metabolic stress and ageing 
    Gilmour, Brian Christopher; Gudmundsrud, Ruben; Frank, Johannes; Hov, Amund; Hindkjær Lautrup, Sofie; Aman, Yahyah; Røsjø, Helge; Brenner, Charles; Ziegler, Mathias; Tysnes, Ole-Bjørn; Tzoulis, Charalampos; Omland, Torbjørn; Søraas, Arne Vasli; Holmøy, Trygve; Bergersen, Linda Hildegard; Storm-Mathisen, Jon; Nilsen, Hilde; Fang, Evandro Fei (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2020)
    Nicotinamide adenine dinucleotide (NAD+) plays a fundamental role in life and health through the regulation of energy biogenesis, redox homeostasis, cell metabolism, and the arbitration of cell survival via linkages to ...
  • Targeting PBK/TOPK decreases growth and survival of glioma initiating cells in vitro and attenuates tumor growth in vivo 
    Joel, Mrinal; Mughal, Awais A; Grieg, Zanina; Murrell, Wayne; Palmero, Sheryl; Mikkelsen, Birthe; Fjerdingstad, Hege B; Sandberg, Cecilie J; Behnan, Jinan; Glover, Joel C; Langmoen, Iver A; Stangeland, Biljana (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)
    Background Glioblastomas are invasive therapy resistant brain tumors with extremely poor prognosis. The Glioma initiating cell (GIC) population contributes to therapeutic resistance and tumor recurrence. ...
  • TBK1-mediated phosphorylation of LC3C and GABARAP-L2 controls autophagosome shedding by ATG4 protease 
    Herhaus, Lina; Bhaskara, Ramachandra M; Lystad, Alf Håkon; Gestal-Mato, Uxia; Covarrubias-Pinto, Adriana; Bonn, Florian; Simonsen, Anne; Hummer, Gerhard; Dikic, Ivan (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
    Autophagy is a highly conserved catabolic process through which defective or otherwise harmful cellular components are targeted for degradation via the lysosomal route. Regulatory pathways, involving post‐translational ...
  • TCR repertoire diversity in Multiple Sclerosis: High-dimensional bioinformatics analysis of sequences from brain, cerebrospinal fluid and peripheral blood 
    Amoriello, Roberta; Chernigovskaia, Mariia; Greiff, Victor; Carnasciali, Alberto; Massacesi, Luca; Barilaro, Alessandro; Repice, Anna Maria; Biagioli, Tiziana; Aldinucci, Alessandra; Muraro, Paolo A.; Laplaud, David-Axel; Lossius, Andreas; Ballerini, Clara (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
    Background T cells play a key role in the pathogenesis of multiple sclerosis (MS), a chronic, inflammatory, demyelinating disease of the central nervous system (CNS). Although several studies recently investigated the ...
  • Teachers’ perspectives on the EU Fruit and Vegetable Scheme implementation in Italy 
    Vitali, Veronica; Tiboldo, Giulia; Castellari, Elena; Meshkovska, Biljana (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2023)
    Objective: School-based fruit and vegetable provision programmes can improve children’s eating patterns and health by ensuring access to fruit and vegetables and providing nutrition education. However, the effectiveness ...
  • Tear film break-up time and dry eye disease severity in a large norwegian cohort 
    Yazdani, Mazyar; Fiskådal, Jørgen; Chen, Xiangjun; Utheim, Øygunn Aass; Ræder, Sten; Vitelli, Valeria; Utheim, Tor Paaske (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
    This study evaluated to what extent tear film break-up time (TFBUT) could discriminate pathological scores for other clinical tests and explore the associations between them. Dry eye patients (n = 2094) were examined for ...
  • Technical recommendations to perform the alkaline standard and enzyme-modified comet assay in human biomonitoring studies 
    Azqueta, Amaya; Muruzabal, Damian; Boutet-Robinet, Elisa; Milic, Mirta; Dusinska, Maria; Brunborg, Gunnar; Møller, Peter; Collins, Andrew R. (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2019)
    The comet assay (single cell gel electrophoresis) is widely used as a biomonitoring tool to assess DNA damage – strand breaks, as well as oxidised bases; it can also be adapted to measure DNA repair. It is based on the ...
  • TECPR1 is activated by damage-induced sphingomyelin exposure to mediate noncanonical autophagy 
    Kaur, Namrita; de la Ballina, Laura R; Haukaas, Håvard Styrkestad; Torgersen, Maria Lyngaas; Radulovic, Maja; Munson, Michael J; Sabirsh, Alan; Stenmark, Harald Alfred; Simonsen, Anne Gjøen; Carlsson, Sven R; Lystad, Alf Håkon Lohsen (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
    Abstract Cells use noncanonical autophagy, also called conjugation of ATG8 to single membranes (CASM), to label damaged intracellular compartments with ubiquitin‐like ATG8 family proteins in order to signal danger caused ...
  • Television viewing and exposure to food-related commercials among European school children, associations with fruit and vegetable intake: a cross sectional study 
    Klepp, Knut-Inge; Wind, Marianne; de Bourdeaudhuij, Ilse; Rodrigo, Carmen P; Due, Pernille; Bjelland, Mona; Brug, Johannes (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2007)
    Background Fruit and vegetable intake is low among European children and exposure to TV is negatively associated with the intake of fruit and vegetables. The aim of the present study was to explore exposure ...
  • Telomere length and association with age, gender and cardiovascular disease in patients with Familial HypercholesterolemiaRestricted Access 
    Hansen, Anna Lena (Master thesis / Masteroppgave, 2021)
  • Temporal patterns in count-to-ten fetal movement charts and their associations with pregnancy characteristics: a prospective cohort study 
    Winje, Brita A; Røislien, Jo; Frøen, J F (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2012)
    Background Fetal movement counting has long been suggested as a screening tool to identify impaired placental function. However, quantitative limits for decreased fetal movement perform poorly for screening ...
  • Temporal patterns of circulating cell-free DNA (cfDNA) in a newborn piglet model of perinatal asphyxia 
    Manueldas, Sophia; Benterud, Torkil; Rueegg, Corina Silvia; Garberg, Håvard Tetlie; Huun, Marianne Ullestad; Pankratov, Leonid; Atneosen-Åsegg, Monica; Solberg, Rønnaug; Escobar, Javier; Saugstad, Ola Didrik; Baumbusch, Lars Oliver (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
    Heart failure is associated with low cardiac output (CO) and low brain perfusion that imposes a significant risk for accelerated brain ageing and Alzheimer’s disease (AD) development. Although clinical heart failure can ...
  • Temporal processing in the visual cortex of the awake and anesthetized rat 
    Aasebø, Ida E. J.; Lepperød, Mikkel Elle; Stavrinou, Maria; Nøkkevangen, Sandra; Einevoll, Gaute; Hafting, Torkel; Fyhn, Marianne (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
    The activity pattern and temporal dynamics within and between neuron ensembles are essential features of information processing and believed to be profoundly affected by anesthesia. Much of our general understanding of ...
  • Temporal trends in age at menarche and age at menopause: a population study of 312 656 women in Norway 
    Gottschalk, Marthe Sørli; Eskild, Anne; Hofvind, Solveig; Gran, Jon Michael; Bjelland, Elisabeth Krefting (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
    Abstract STUDY QUESTION Have mean age at menarche or mean age at natural menopause changed from the 1939 birth cohort to the 1964 birth cohort? SUMMARY ...
  • Ten year neurocognitive trajectories in first-episode psychosis 
    Barder, Helene; Sundet, Kjetil Søren; Rund, Bjørn Rishovd; Evensen, Julie Horgen; Haahr, Ulrik; Hegelstad, Wenche; Joa, Inge; Johannessen, Jan Olav; Langeveld, Johannes H.; Larsen, Tor Ketil; Melle, Ingrid; Ilner, Stein E. Opjordsmoen; Røssberg, Jan Ivar; Simonsen, Erik; Vaglum, Per Jørgen Wiggen; McGlashan, Thomas; Friis, Svein (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2013)
    Objective: Neurocognitive impairment is commonly reported at onset of psychotic disorders. However, the long-term neurocognitive course remains largely uninvestigated in first episode psychosis (FEP) and the relationship ...
  • Terminal digit preference: a source of measurement error in breast cancer diameter reporting 
    Tsuruda, Kaitlyn; Hofvind, Solveig; Akslen, Lars A.; Hoff, Solveig Roth; Veierød, Marit Bragelien (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
    Objectives: Women diagnosed with breast cancer are offered treatment and therapy based on tumor characteristics, including tumor diameter. There is scarce knowledge whether tumor diameter is accurately reported, or whether ...
  • Test-retest reproducibility of a food frequency questionnaire (FFQ) and estimated effects on disease risk in the Norwegian Women and Cancer Study (NOWAC) 
    Parr, Christine L; Veierød, Marit B; Laake, Petter; Lund, Eiliv; Hjartåker, Anette (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2006)
    Background The Norwegian Women and Cancer Study (NOWAC) is a national population-based cohort study with 102 443 women enrolled at age 30–70 y from 1991 to 1997. The present study was a methodological ...
  • The "smoker's paradox" in patients with acute coronary syndrome: a systematic review 
    Aune, Erlend; Røislien, Jo; Mathisen, Mariann; Thelle, Dag S; Erik Otterstad, Jan (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2011)
    Background Smokers have been shown to have lower mortality after acute coronary syndrome than non-smokers. This has been attributed to the younger age, lower co-morbidity, more aggressive treatment and lower ...
  • The ABL-MYC axis controls WIPI1-enhanced autophagy in lifespan extension 
    Sporbeck, Katharina; Haas, Maximilian L.; Pastor-Maldonado, Carmen J.; Schüssele, David S.; Hunter, Catherine; Takacs, Zsuzsanna; Diogo de Oliveira, Ana L.; Franz-Wachtel, Mirita; Charsou, Chara; Pfisterer, Simon G.; Gubas, Andrea; Haller, Patricia K.; Knorr, Roland L.; Kaulich, Manuel; Macek, Boris; Eskelinen, Eeva-Liisa; Simonsen, Anne Gjøen; Proikas-Cezanne, Tassula (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
    Abstract Human WIPI β-propellers function as PI3P effectors in autophagy, with WIPI4 and WIPI3 being able to link autophagy control by AMPK and TORC1 to the formation of autophagosomes. WIPI1, instead, assists WIPI2 in ...
  • The Adenoviral E1B-55k Protein Present in HEK293 Cells Mediates Abnormal Accumulation of Key WNT Signaling Proteins in Large Cytoplasmic Aggregates 
    Olsen, Petter Angell; Krauss, Stefan Johannes Karl (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
    HEK293 cells are one of the most widely used cell lines in research, and HEK293 cells are frequently used as an in vitro model for studying the WNT signaling pathway. The HEK293 cell line was originally established by ...