Now showing items 2430-2449 of 3159

  • Linkevicius, Marius; Bonnin, Rémy A; Alm, Erik; Svartström, Olov; Apfalter, Petra; Hartl, Rainer; Hasman, Henrik; Roer, Louise; Räisänen, Kati; Dortet, Laurent; Pfennigwerth, Niels; Hans, Jörg B; Tóth, Ákos; Buzgó, Lilla; Cormican, Martin; Delappe, Niall; Monaco, Monica; Giufrè, Maria; Hendrickx, Antoni Pa; Samuelsen, Ørjan; Pöntinen, Anna Kaarina; Caniça, Manuela; Manageiro, Vera; Oteo-Iglesias, Jesús; Pérez-Vázquez, María; Westmo, Karin; Mäkitalo, Barbro; Palm, Daniel; Monnet, Dominique L.; Kohlenberg, Anke (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
    Whole genome sequencing data of 874 Escherichia coli isolates carrying bla NDM-5 from 13 European Union/European Economic Area countries between 2012 and June 2022 showed the predominance of sequence types ...
  • Kohl, Yvonne; William, Nicola; Elje, Elisabeth; Backes, Nadine; Rothbauer, Mario; Srancikova, Annamaria; Rundén-Pran, Elise; El Yamani, Naouale; Korenstein, Rafi; Madi, Lea; Barbul, Alexander; Kozics, Katarina; Sramkova, Monika; Steenson, Karen; Gabelova, Alena; Ertl, Peter; Dusinska, Maria; Nelson, Andrew (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
    This study compares the performance and output of an electrochemical phospholipid membrane platform against respective in vitro cell-based toxicity testing methods using three toxicants of different biological action ...
  • Züchner, Mark; Kondratska, Olena; Sylte, Camilla; Glover, Joel; Boulland, Jean-Luc (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2018)
    Following incomplete compression injury in the thoracic spinal cord of neonatal mice 1 day after birth (P1), we previously reported that virtually normal hindlimb locomotor function is recovered within about 3 weeks despite ...
  • Fjerdingstad, Hege Brincker; Glover, Joel Clinton (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
    Human pluripotent stem cells (human embryonic stem cells, hESCs, and human induced pluripotent stem cells, hiPSCs) were originally cultured on different types of feeder cells for maintenance in an undifferentiated state ...
  • Ho, Ai Van Thuy; Toska, Karin; Wesche, Jarlis (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
    Purpose: The aim of the study was to investigate steady state levels, dynamics and reproducibility of cardiovascular variables and electrodermal activity in different skin areas in response to minor physiological and mental ...
  • Burns, Daniel; Anokian, Ezequiel; Saunders, Edward J.; Bristow, Robert G.; Fraser, Michael; Reimand, Jüri; Schlomm, Thorsten; Sauter, Guido; Brors, Benedikt; Korbel, Jan; Weischenfeldt, Joachim; Waszak, Sebastian Martin; Corcoran, Niall M.; Jung, Chol-Hee; Pope, Bernard J.; Hovens, Chris M.; Cancel-Tassin, Géraldine; Cussenot, Olivier; Loda, Massimo; Sander, Chris; Hayes, Vanessa M.; Dalsgaard Sorensen, Karina; Lu, Yong-Jie; Hamdy, Freddie C.; Foster, Christopher S.; Gnanapragasam, Vincent; Butler, Adam; Lynch, Andy G.; Massie, Charlie E.; Woodcock, Dan J.; Cooper, Colin S.; Wedge, David C.; Brewer, Daniel S.; Kote-Jarai, Zsofia; Eeles, Rosalind A. (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
    Background Germline variants explain more than a third of prostate cancer (PrCa) risk, but very few associations have been identified between heritable factors and clinical progression. Objective To find rare germline ...
  • Parnell, Laurence D.; McCaffrey, Kira S.; Brooks, Athena W.; Smith, Caren E.; Lai, Chao-Qiang; Christensen, Jacob J.; Wiley, Christopher D.; Ordovas, Jose M. (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
    Introduction: Rate-limiting enzymes (RLEs) are innate slow points in metabolic pathways, and many function in bio-processes related to nutrient sensing. Many RLEs carry causal mutations relevant to inherited metabolic ...
  • Lefevre, Sjannie; Stecyk, Jonathan A. W.; Torp, May-Kristin; Løvold, Lisa Yuen; Sørensen, Christina; Johansen, Ida Beitnes; Stensløkken, Kåre-Olav; Couturier, Christine; Sloman, Katherine A.; Nilsson, Göran Erik (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
    Crucian carp (Carassius carassius) survive without oxygen for several months, but it is unknown whether they are able to protect themselves from cell death normally caused by the absence, and particularly return, of oxygen. ...
  • Kelly, Liam; Twohig, Cliona; Woods, Cathrine B.; Luszczynska, Aleksandra; Murrin, Celine M.; Lien, Nanna; Meshkovska, Biljana; Kamphuis, Carlijn B.M.; Poelman, Maartje; Terragani, Laura; Forberger, Sarah; Hebestreit, Antje; Ahrens, Wolfgang; Harrington, Janas M. (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
    Abstract Background An upsurge in policy evaluation research within public health sciences has led to multi-disciplinary research networks like the ‘Policy Evaluation Network’ (PEN). This ...
  • Kocere, Agnese; Resseguier, Julien; Wohlmann, Jens; Skjeldal, Frode Miltzow; Khan, Shanawaz; Speth, Martin; Dal, Nils-Jørgen Knudsen; Ng, Matthew Yoke Wui; Alonso Rodriguez, Noelia; Scarpa, Edoardo; Rizzello, Loris; Battaglia, Giuseppe; Griffiths, Gareth Wyn; Fenaroli, Federico (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
    Background The developing zebrafish is an emerging tool in nanomedicine, allowing non-invasive live imaging of the whole animal at higher resolution than is possible in the more commonly used mouse models. In addition, ...
  • Elgaaen, Bente Vilming; Dahl, Jørgen Fallås; Bentzen, Anne Gry; Ingebrigtsen, Vibeke Anett; Nilsen, Elisabeth Berge; Vistad, Ingvild; Dørum, Anne; Popova, Olesya; Bjørge, Line; Zucknick, Manuela; Aune, Guro; Lindemann, Kristina Yvonne Kathe (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
    Objectives The aim of this study was to provide real-world efficacy and safety data on niraparib maintenance treatment in patients with non-germline (gBRCA)1/2 mutated platinum-sensitive recurrent ovarian cancer. Methods ...
  • Nahalomo, Aziiza; Iversen, Per O; Rukundo, Peter M; Kaaya, Archileo; Kikafunda, Joyce; Eide, Wenche B; Marais, Maritha; Wamala, Edward; Kabahenda, Margaret (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
    Background In developing countries like Uganda, the human right to adequate food (RtAF) is inextricably linked to access to land for households to feed themselves directly through production or means for ...
  • Rambøl, Mia Marie-Elisabeth; Hisdal, Jonny; Sundhagen, Jon Otto; Brinchmann, Jan E.; Rosales, Antonio (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
    Vascular disease is a major cause of death worldwide, and the growing need for replacement vessels is not fully met by autologous grafts or synthetic alternatives. Tissue engineering has emerged as a compelling strategy ...
  • Christen, Salome; Roser, Katharina; Mulder, Renee L.; Ilic, Anica; Lie, Hanne Cathrine; Loonen, Jacqueline J.; Mellblom, Anneli; Kremer, Leontien; Hudson, Melissa M.; Constine, Louis Sandy; Skinner, Roderick; Scheinemann, Katrin; Gilleland Marchak, Jordan; Michel, Gisela (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
    Abstract Purpose Cancer-related fatigue (CRF) negatively affects the lives of childhood, adolescent, and young adult (CAYA) cancer survivors. We aimed to provide an evidence-based clinical practice guideline (CPG) ...
  • Danbolt, Niels Christian; López-Corcuera, Beatriz; Zhou, Yun (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
    Abstract In contrast to water soluble enzymes which can be purified and studied while in solution, studies of solute carrier (transporter) proteins require both that the protein of interest is situated in a phospholipid ...
  • Paganini, Julian A.; Plantinga, Nienke L.; Alonso, Sergio Arredondo; Willems, Rob; Schürch, Anita C. (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
    The incidence of infections caused by multidrug-resistant E. coli strains has risen in the past years. Antibiotic resistance in E. coli is often mediated by acquisition and maintenance of plasmids. The study of E. coli ...
  • Bröer, Christian; Ayuandini, Sherria; Baillergeau, Evelyne; Moerman, Gerben; Veltkamp, Gerlieke; Luszczynska, Aleksandra; Ljøsne, Isabelle Sylvie Budin; Rito, Ana Isabel; Stensdal, Maja; Lien, Nanna; Klepp, Knut Inge (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
    The CO-CREATE project aims to collaborate with adolescents across Europe in developing policy ideas that contribute to overweight and obesity prevention. In this paper, we present the theoretical basis and methodological ...
  • Melsom, Helene Støle; Heiestad, Christina Mathisen; Eftestøl, Einar; Torp, May-Kristin; Gundersen, Kristian; Bjørnebekk, Astrid; Thorsby, Per Medbøe; Stensløkken, Kåre-Olav; Hisdal, Jonny (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
    Abstract High-doses of anabolic–androgenic steroids (AAS) is efficient for building muscle mass, but pose a risk of cardiovascular side effects. Little is known of the effect of AAS on vasculature, but previous findings ...
  • Hutin, David; Hagen, Karoline Alvik; Shao, Peng; Sugamori, Kim; Grant, Denis M.; Matthews, Jason (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
    Poly-ADP-ribose polymerases (PARPs) are important regulators of the immune system, including TCDD-inducible poly-ADP-ribose polymerase (TIPARP), also known as poly-ADP-ribose polymerase 7 (PARP7). PARP7 negatively regulates ...
  • Azulay, Naomi; Bjørkholt Olsen, Roy; Nielsen, Christopher Sivert; Stubhaug, Audun; Jenssen, Trond Geir; Schirmer, Henrik; Frigessi, Arnoldo; Rosseland, Leiv Arne; Tronstad, Christian (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
    Abstract Both diabetes mellitus (DM) and the metabolic syndrome (MetS) are associated with autonomic neuropathy, which predisposes to cardiac events and death. Measures of heart rate variability (HRV) can be used to monitor ...