Now showing items 2114-2133 of 3159

  • Djordjilović, Vera; Hemerik, Jesse; Thoresen, Magne (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
    Mediation analysis in high-dimensional settings often involves identifying potential mediators among a large number of measured variables. For this purpose, a two-step familywise error rate procedure called ScreenMin has ...
  • Huitfeldt, Anders; Stensrud, Mats J; Suzuki, Etsuji (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
    The relationship between collapsibility and confounding has been subject to an extensive and ongoing discussion in the methodological literature. We discuss two subtly different definitions of collapsibility, and show that ...
  • Wood, Thomas (Doctoral thesis / Doktoravhandling, 2017)
  • Møller, Peter; Loft, Steffen; Ersson, Clara; Koppen, Gudrun; Dusinska, Maria; Collins, Andrew Richard (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)
    The comet assay has developed over the past 30 years and today, a variety of different DNA lesions and DNA repair can be measured by different versions of the assay (Collins, 2004). In the final step of the method, an image ...
  • Murphy, Ricardo (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2017)
    There is a tendency to automatically use two-sided tests to assess the statistical significance of experimental results. Yet if a theory predicts the direction of an experimental outcome, or if for some practical (eg ...
  • Nestvold, Janne M.; Wang, Mengyu; Camilio, Ketil Andre; Zinöcker, Severin; Tjelle, Torunn Elisabeth; Lindberg, Alf; Haug, Bengt Erik; Kvalheim, Gunnar; Sveinbjørnsson, Baldur; Rekdal, Øystein (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
    LTX 315 is an oncolytic peptide with potent immunological properties. In the present study, we demonstrate that intratumoral treatment with LTX-315 resulted in a complete regression and systemic immune response in a rat ...
  • Bere, Elling; te Velde, Saskia J; Småstuen, Milada C; Twisk, Jos; Klepp, Knut-Inge (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)
    Background It is important that health-promoting efforts result in sustained behavioural changes, preferably throughout life. However, only a very few intervention studies evaluate long term follow up. ...
  • Dörje, Christina; Mjøen, Geir; Strøm, Erik Heyerdahl; Holdaas, Hallvard; Jenssen, Trond Geir; Øyen, Ole; Akkøk, Cigdem Ahaein; Småstuen, Milada C; Midtvedt, Karsten; Reisæter, Anna Varberg (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)
    Introduction Early acute antibody-mediated rejection (ABMR) occurs more frequently in ABO-incompatible (ABOi) than in ABO-compatible (ABOc) kidney transplantation. This could lead to increased inflammation/scarring in ...
  • Toch, Mathilde; Harris, Audrey; Schakman, Olivier; Kondratskaya, Elena; Dauguet, Nicolas; Boulland, Jean-Luc; Debrulle, Stéphanie; Baudouin, Charlotte; Hidalgo-Figueroa, Maria; Mu, Xiuqian; Gow, Alexander; Glover, Joel; Tissir, Fadel; Clotman, Frédéric (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
    Abstract In the developing spinal cord, Onecut transcription factors control the diversification of motor neurons into distinct neuronal subsets by ensuring the maintenance of Isl1 expression during differentiation. However, ...
  • Braathen, Martin; Rimstad, Ivan Jonassen; Dybvik, Terje; Nygård, Ståle; Ræder, Johan (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
    Background Ion mobility spectrometry (IMS) allows for online quantification of exhaled propofol concentrations. We aimed to validate a bedside online IMS device, the Edmon®, for predicting plasma concentrations of propofol ...
  • Rogne, Marie; Chu, Dinh Toi; Küntziger, Thomas M.; Mylonakou, Maria-Niki; Collas, Philippe; Tasken, Kjetil (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
    Optic atrophy 1 (OPA1) is the A-kinase anchoring protein targeting the pool of protein kinase A (PKA) responsible for perilipin 1 phosphorylation, a gatekeeper for lipolysis. However, the involvement of OPA1-bound PKA in ...
  • Caglayan, Safak; Hashim, Adnan; Cieslar-Pobuda, Artur; Jensen, Vidar; Behringer, Sidney; Talug, Burcu; Chu, Dinh Toi; Pecquet, Christian; Rogne, Marie; Brech, Andreas; Brorson, Sverre Henning; Nagelhus, Erlend Arnulf; Hannibal, Luciana; Boschi, Antonella; Tasken, Kjetil; Staerk, Judith (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
    Optic atrophy 1 (OPA1), a GTPase at the inner mitochondrial membrane involved in regulating mitochondrial fusion, stability, and energy output, is known to be crucial for neural development: Opa1 heterozygous mice show ...
  • Németh, Enikő; Gyuricza, Barbara; Forgács, Viktória; Cumming, Paul; Henriksen, Gjermund; Marton, János; Bauer, Beate; Mikecz, Pál; Fekete, Anikó (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
    We have established a method for nucleophilic one-pot, two-step radiosynthesis of the popular opioid receptor radioligand 6-O-(2-[18F]fluoroethyl)-6-O-desmethyl-diprenorphine ([18F]FE-DPN) from the novel precursor ...
  • Lepperød, Mikkel Elle; Christensen, Ane Charlotte; Lensjø, Kristian Kinden; Buccino, Alessio Paolo; Yu, Jai; Fyhn, Marianne; Hafting, Torkel (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
    Grid cells in the medial entorhinal cortex (MEC) exhibit remarkable spatial activity patterns with spikes coordinated by theta oscillations driven by the medial septal area (MSA). Spikes from grid cells progress relative ...
  • Kogler, Stian; Aizenshtadt, Aleksandra; Harrison, Sean; Skottvoll, Frøydis Sved; Berg, Henriette Engen; Abadpour, Shadab; Scholz, Hanne; Sullivan, Gareth John; Thiede, Bernd; Lundanes, Elsa; Bogen, Inger Lise; Krauss, Stefan Johannes Karl; Røberg-Larsen, Hanne; Wilson, Steven Ray Haakon (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
    Organoids, i.e., laboratory-grown organ models developed from stem cells, are emerging tools for studying organ physiology, disease modeling, and drug development. On-line analysis of organoids with mass spectrometry would ...
  • Hoddevik, Eystein Hellstrøm; Rao, Shreyas Balachandra; Rahmani, Soulmaz; Boldt, Henning Bunsow; Ottersen, Ole Petter; Amiry-Moghaddam, Mahmood (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
    Abstract Evidence suggests that extracellular matrix molecules of perivascular basal laminae help orchestrate the molecular assemblies at the gliovascular interface. Specifically, laminin and agrin are thought to tether ...
  • Jacobsen, Bente; Kleven, Heidi; Gatome, Wairimu; Las, Liora; Ulanovsky, Nachum; Witter, Menno Peter (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
    Abstract The hippocampal formation and entorhinal cortex are crucially involved in learning and memory as well as in spatial navigation. The conservation of these structures across the entire mammalian lineage demonstrates ...
  • Kogler, Stian; Kømurcu, Kristina Sæterdal; Olsen, Christine Sandsnes; Shoji, Jun-ya; Skottvoll, Frøydis Sved; Krauss, Stefan Johannes Karl; Wilson, Steven Ray Haakon; Røberg-Larsen, Hanne (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
    Organoids are 3D models of organs, grown in the laboratory from stem cells. An organ model grown/placed in microfluidic devices is commonly termed an “organ-on-a-chip”. Organoids and organ-on-a-chip devices are becoming ...
  • Stahl, Katja; Skare, Oivind; Torp, Reidun (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2009)
    Organotypic cultures from the ventral mesencephalon (VM) are widely used to model Parkinson’s disease (PD). In this method, neurotoxic compounds have traditionally been applied to the media to induce a uniform dopaminergic ...
  • Johansen, Espen B; Killeen, Peter R; Russell, Vivienne A; Tripp, Gail; Wickens, Jeff R; Tannock, Rosemary; Williams, Jonathan; Sagvolden, Terje (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2009)
    Attention-deficit/hyperactivity disorder (ADHD), characterized by hyperactivity, impulsiveness and deficient sustained attention, is one of the most common and persistent behavioral disorders of childhood. ADHD is associated ...