Browsing Institutt for medisinske basalfag by Title
Now showing items 1674-1693 of 3159
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(Master thesis / Masteroppgave, 2023)Et viktig mål med hjemmebaserte helsetjenester er å gi tjenester slik at eldre mennesker kan bo hjemme så lenge som mulig. Dette målet forutsetter god helse blant eldre. En av faktorene som spiller en viktig rolle for å ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)Motivation: Estimation of the hidden population structure is an important step in many genetic studies. Often the aim is also to identify which sequence locations are the most discriminative between groups of samples for ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)K+-channels of the Kv7/KCNQ-family hyperpolarize and stabilize excitable cells such as autonomic neurons and vascular smooth muscle cells (VSMC). Kv7 may therefore play a role in blood pressure (BP) homeostasis, and prevent ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2008)Background ADHD is currently defined as a cognitive/behavioral developmental disorder where all clinical criteria are behavioral. Overactivity, impulsiveness, and inattentiveness are presently regarded as ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)Current studies addressing the influence of interleukin-33 or its receptor (IL-33R/ST2) on development of atopic dermatitis-like inflammation in mice have reported conflicting results. We compared the response in single- ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)Neonatal cerebral hypoxia-ischemia (HI) is the leading cause of death and disability in newborns with the only current treatment being hypothermia. An increased understanding of the pathways that facilitate tissue repair ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)Cerebral malaria (CM), caused by Plasmodium falciparum infection, is a prevalent neurological disorder in the tropics. Most of the patients are children, typically with intractable seizures and high mortality. Current ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2012)Background Lactation has beneficial short term effects on maternal metabolic health, but the long term effects are less well known. Methods We ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)At the nuclear periphery, the genome is anchored to A- and B-type nuclear lamins in the form of heterochromatic lamina-associated domains. A-type lamins also associate with chromatin in the nuclear interior, away from the ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)At the nuclear periphery, associations of chromatin with the nuclear lamina through lamina-associated domains (LADs) aid functional organization of the genome. We review the organization of LADs and provide evidence of LAD ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)Abstract It has been suggested that consciousness is closely related to the complexity of the brain. The perturbational complexity index (PCI) has been used in humans and rodents to distinguish conscious from unconscious ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)The nuclear lamina contributes to the regulation of gene expression and to chromatin organization. Mutations in A-type nuclear lamins cause laminopathies, some of which are associated with a loss of heterochromatin at the ...
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(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2019)In non-Markov multi-state models, the traditional Aalen–Johansen (AJ) estimator for state transition probabilities is generally not valid. An alternative, suggested by Putter and Spitioni, is to analyse a subsample of the ...
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(Doctoral thesis / Doktoravhandling, 2023)Landslides predispose individuals from low-resource communities to risk factors that may lead to poor nutritional health. A mixed methods cohort study was conducted to assess landslides and seasonality effects on food ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)Background The role of laparoscopy in the treatment of intrahepatic cholangiocarcinoma (ICC) remains unclear. This multicenter study examined the outcomes of laparoscopic liver resection for ICC. Methods Patients ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)Abstract Background The optimal operative treatment for umbilical and epigastric hernia, i.e., primary midline ventral hernia (PMVH), is debatable. The most common techniques are the primary suture ...
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(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2019)Hepatitis C virus (HCV) virions contain a subset of host liver cells proteome often composed of interesting virus-interacting factors. A proteomic analysis performed on double gradient-purified clinical HCV highlighted the ...
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(Doctoral thesis / Doktoravhandling, 2024)With current treatment, Hodgkin’s lymphoma is a curable disease. However, survivors live with increased risk of developing late effects. With increasing numbers of cancer survivors in general, survivorship care is a challenge ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)Background and aims Despite lipid lowering therapy (LLT), reaching LDL-C targets in patients with familial hypercholesterolemia (FH) remains challenging. Our aim was to determine attainment of LDL-C target levels and ...
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(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2019)Current treatment goals for familial hypercholesterolemia (FH) recommended by the European Atherosclerosis Society (EAS) are LDL-C ≤2.5 mmol/L (∼100 mg/dL) or ≤1.8 mmol/L (∼70 mg/dL) in very high-risk subjects. Objective The ...