Browsing Institutt for medisinske basalfag by Title

Now showing items 1301-1320 of 3159

  • Gene expression is differentially regulated in skeletal muscle and circulating immune cells in response to an acute bout of high-load strength exercise 
    Gjevestad, Gyrd O; Hamarsland, Håvard; Raastad, Truls; Ottestad, Inger; Christensen, Jacob J; Eckardt, Kristin; Drevon, Christian A; Biong, Anne S; Ulven, Stine M; Holven, Kirsten B (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
    Background High-intensity exercise induces many metabolic responses. In is unknown whether the response in the peripheral blood mononuclear cells (PBMCs) reflects the response in skeletal muscle and whether ...
  • Gene expression profiles in preterm infants on continuous long-term oxygen therapy suggest reduced oxidative stress-dependent signaling during hypoxia 
    Kalikstad, Betty; Kultima, Hanna Goransson; Andersstuen, Terese; Klungland, Arne; Isaksson, Anders (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
    Preterm infants are susceptible to neonatal inflammatory/infective diseases requiring drug therapy. The present study hypothesized that mRNA expression in the blood may be modulated by signaling pathways during treatment. ...
  • Gene expression profiles of breast biopsies from healthy women identify a group with claudin-low features 
    Haakensen, Vilde D; Christian Lingjærde, Ole; Lüders, Torben; Riis, Margit; Prat, Aleix; Troester, Melissa A; Holmen, Marit M; Ole Frantzen, Jan; Romundstad, Linda; Navjord, Dina; Bukholm, Ida K; Johannesen, Tom B; Perou, Charles M; Ursin, Giske; Kristensen, Vessela N; Børresen-Dale, Anne-Lise; Helland, Åslaug (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2011)
    Background Increased understanding of the variability in normal breast biology will enable us to identify mechanisms of breast cancer initiation and the origin of different subtypes, and to better predict ...
  • Gene Regulatory Interactions at Lamina-Associated Domains 
    Madsen-Østerbye, Julia-Kristina; Abdelhalim, Mohamed Ibrahim Mohamed; Hazell Pickering, Sarah Jai; Collas, Philippe (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
    The nuclear lamina provides a repressive chromatin environment at the nuclear periphery. However, whereas most genes in lamina-associated domains (LADs) are inactive, over ten percent reside in local euchromatic contexts ...
  • General and PKU-specific quality of life and fatigue in early-treated adults with phenylketonuria in NorwayRestricted Access 
    Verhaug, Maia (Master thesis / Masteroppgave, 2022)
  • General Anesthesia Disrupts Complex Cortical Dynamics in Response to Intracranial Electrical Stimulation in Rats 
    Arena, Alessandro; Comolatti, Renzo; Thon, Sarah Kriebel; Casali, Adenauer G.; Storm, Johan Frederik (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
    The capacity of human brain to sustain complex cortical dynamics appears to be strongly associated with conscious experience and consistently drops when consciousness fades. For example, several recent studies in humans ...
  • Genetic and hormonal Control of hepatic steatosis in female and male mice 
    Norheim, Frode; Hui, Simon T; Kulahcioglu, Emre; Mehrabian, Margarete; Cantor, Rita M; Pan, Calvin; Parks, Brian W; Lusis, Aldons J (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
    The etiology of nonalcoholic fatty liver disease is complex and influenced by factors such as obesity, insulin resistance, hyperlipidemia, and sex. We now report a study on sex difference in hepatic steatosis in the context ...
  • Genetic architecture of fusarium head blight disease resistance and associated traits in Nordic spring wheat 
    Nannuru, Vinay Kumar Reddy; Windju, Susanne Skinnehaugen; Belova, Tatiana; Dieseth, Jon Arne; Alsheikh, Muath K; Dong, Yanhong; McCartney, Curt A.; Henriques, Maria Antonia; Buerstmayr, Hermann; Michel, Sebastian; Meuwissen, Theodorus; Lillemo, Morten (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
    Abstract Key message This study identified a significant number of QTL that are associated with FHB disease resistance in NMBU spring wheat panel by conducting genome-wide association study. ...
  • The genetic architecture of NAFLD among inbred strains of mice 
    Hui, Simon T; Parks, Brian W; Org, Elin; Norheim, Frode; Che, Nam; Pan, Calvin; Castellani, Lawrence W; Charugundla, Sarada; Dirks, Darwin L; Psychogios, Nikolaos; Neuhaus, Isaac; Gerszten, Robert E; Kirchgessner, Todd; Gargalovic, Peter S; Lusis, Aldons J (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)
    To identify genetic and environmental factors contributing to the pathogenesis of non-alcoholic fatty liver disease, we examined liver steatosis and related clinical and molecular traits in more than 100 unique inbred mouse ...
  • Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function 
    Pattaro, Cristian; Teumer, Alexander; Gorski, Mathias; Chu, Audrey Y.; Li, Man; Mijatovic, Vladan; Garnaas, Maija; Tin, Adrienne; Sorice, Rossella; Li, Yong; Taliun, Daniel; Olden, Matthias; Foster, Meredith; Yang, Qiong; Chen, Ming-Huei; Pers, Tune H.; Johnson, Andrew D.; Ko, Yi-An; Fuchsberger, Christian; Tayo, Bamidele; Nalls, Michael; Feitosa, Mary F.; Isaacs, Aaron; Dehghan, Abbas; D'Adamo, Pio; Adeyemo, Adebowale; Dieffenbach, Aida Karina; Zonderman, Alan B.; Nolte, Ilja M.; van der Most, Peter J.; Wright, Alan F.; Shuldiner, Alan R.; Morrison, Alanna C.; Hofman, Albert; Smith, Albert V.; Dreisbach, Albert W.; Franke, Andre; Uitterlinden, André G.; Metspalu, Andres; Tonjes, Anke; Lupo, Antonio; Robino, Antonietta; Johansson, Åsa; Demirkan, Ayse; Kollerits, Barbara; Freedman, Barry I.; Ponte, Belen; Oostra, Ben A.; Paulweber, Bernhard; Krämer, Bernhard K.; Mitchell, Braxton D.; Buckley, Brendan M.; Peralta, Carmen A.; Hayward, Caroline; Helmer, Catherine; Rotimi, Charles N.; Shaffer, Christian M.; Müller, Christian; Sala, Cinzia; Van Duijn, Cornelia M.; Saint-Pierre, Aude; Ackermann, Daniel; Shriner, Daniel; Ruggiero, Daniela; Toniolo, Daniela; Lu, Yingchang; Cusi, Daniele; Czamara, Darina; Ellinghaus, David; Siscovick, David S; Ruderfer, Douglas; Gieger, Christian; Grallert, Harald; Rochtchina, Elena; Atkinson, Elizabeth J; Holliday, Elizabeth G; Boerwinkle, Eric; Salvi, Erika; Bottinger, Erwin P; Murgia, Federico; Rivadeneira, Fernando; Ernst, Florian; Kronenberg, Florian; Hu, Frank B; Navis, Gerjan J; Curhan, Gary C; Ehret, George B; Homuth, Georg; Coassin, Stefan; Thun, Gian-Andri; Pistis, Giorgio; Gambaro, Giovanni; Malerba, Giovanni; Montgomery, Grant W; Eiriksdottir, Gudny; Jacobs, Gunnar; Li, Guo; Wichmann, H-Erich; Campbell, Harry; Schmidt, Helena; Wallaschofski, Henri; Völzke, Henry; Brenner, Hermann; Kroemer, Heyo K; Kramer, Holly; Lin, Honghuang; Leach, I Mateo; Ford, Ian; Guessous, Idris; Rudan, Igor; Prokopenko, Inga; Borecki, Ingrid; Heid, Iris M; Kolcic, Ivana; Persico, Ivana; Jukema, J Wouter; Wilson, James F; Felix, Janine F; Divers, Jasmin; Lambert, Jean-Charles; Stafford, Jeanette M; Gaspoz, Jean-Michel; Smith, Jennifer A; Faul, Jessica D; Wang, Jie Jin; Ding, Jingzhong; Hirschhorn, Joel N; Attia, John; Whitfield, John B; Chalmers, John; Viikari, Jorma; Coresh, Josef; Denny, Joshua C; Karjalainen, Juha; Fernandes, Jyotika K; Endlich, Karlhans; Butterbach, Katja; Keene, Keith L; Lohman, Kurt; Portas, Laura; Launer, Lenore J; Lyytikäinen, Leo-Pekka; Yengo, Loic; Franke, Lude; Ferrucci, Luigi; Rose, Lynda M; Kedenko, Lyudmyla; Rao, Madhumathi; Struchalin, Maksim; Kleber, Marcus E; Cavalieri, Margherita; Haun, Margot; Cornelis, Marilyn C; Ciullo, Marina; Pirastu, Mario; De Andrade, Mariza; McEvoy, Mark A; Woodward, Mark; Adam, Martin; Cocca, Massimiliano; Nauck, Matthias; Imboden, Medea; Waldenberger, Melanie; Pruijm, Menno; Metzger, Marie; Stumvoll, Michael; Evans, Michele K; Sale, Michele M; Kähönen, Mika; Boban, Mladen; Bochud, Murielle; Rheinberger, Myriam; Verweij, Niek; Bouatia-Naji, Nabila; Martin, Nicholas G; Hastie, Nick; Probst-Hensch, Nicole; Soranzo, Nicole; Devuyst, Olivier; Raitakari, Olli; Gottesman, Omri; Franco, Oscar H; Polasek, Ozren; Gasparini, Paolo; Munroe, Patricia B; Ridker, Paul M; Mitchell, Paul; Muntner, Paul; Meisinger, Christa; Smit, Johannes H; Abecasis, Goncalo R; Adair, Linda S; Alexander, Myriam; Altshuler, David; Amin, Najaf; Arking, Dan E; Arora, Pankaj; Aulchenko, Yurii; Bakker, Stephan JL; Bandinelli, Stefania; Barroso, Ines; Beckmann, Jacques S; Beilby, John P; Bergman, Richard N; Bergmann, Sven; Bis, Joshua C; Boehnke, Michael; Bonnycastle, Lori L; Bornstein, Stefan R; Bots, Michiel L; Bragg-Gresham, Jennifer L; Brand, Stefan-Martin; Brand, Eva; Braund, Peter S; Brown, Morris J; Burton, Paul R; Casas, Juan P; Caulfield, Mark J; Chakravarti, Aravinda; Chambers, John C; Chandak, Giriraj R; Chang, Yen-Pei C; Charchar, Fadi J; Chaturvedi, Nish; Cho, Yoon Shin; Clarke, Robert; Collins, Francis S; Collins, Rory; Connell, John M; Cooper, Jackie A; Cooper, Matthew N; Cooper, Richard S; Corsi, Anna Maria; Dörr, Marcus; Dahgam, Santosh; Danesh, John; Smith, George Davey; Day, Ian NM; Deloukas, Panos; Denniff, Matthew; Dominiczak, Anna F; Dong, Yanbin; Doumatey, Ayo; Elliott, Paul; Elosua, Roberto; Erdmann, Jeanette; Eyheramendy, Susana; Farrall, Martin; Fava, Cristiano; Forrester, Terrence; Fowkes, F Gerald R; Fox, Ervin R; Frayling, Timothy M; Galan, Pilar; Ganesh, Santhi K; Garcia, Melissa; Gaunt, Tom R; Glazer, Nicole L; Go, Min Jin; Goel, Anuj; Grässler, Jurgen; Grobbee, Diederick E; Groop, Leif; Guarrera, Simonetta; Guo, Xiuqing; Hadley, David; Hamsten, Anders; Han, Bok-Ghee; Hardy, Rebecca; Hartikainen, Anna-Liisa; Heath, Simon; Heckbert, Susan R; Hedblad, Bo; Hercberg, Serge; Hernandez, Dena; Hicks, Andrew A; Hilton, Gina; Hingorani, Aroon D; Hoffman Bolton, Judith A; Hopewell, Jemma C; Howard, Philip; Humphries, Steve E; Hunt, Steven C; Hveem, Kristian; Ikram, M Arfan; Islam, Muhammad; Iwai, Naoharu; Jarvelin, Marjo-Riitta; Jackson, Anne U; Jafar, Tazeen H; Janipalli, Charles S; Johnson, Toby; Kathiresan, Sekar; Khaw, Kay-Tee; Kim, Hyung-Lae; Kinra, Sanjay; Kita, Yoshikuni; Kivimaki, Mika; Kooner, Jaspal S; Kumar, MJ Kranthi; Kuh, Diana; Kulkarni, Smita R; Kumari, Meena; Kuusisto, Johanna; Kuznetsova, Tatiana; Laakso, Markku; Laan, Maris; Laitinen, Jaana; Lakatta, Edward G; Langefeld, Carl D; Larson, Martin G; Lathrop, Mark; Lawlor, Debbie A; Lawrence, Robert W; Lee, Jong-Young; Lee, Nanette R; Levy, Daniel; Li, Yali; Longstreth, Will T; Luan, Jian'an; Lucas, Gavin; Ludwig, Barbara; Mangino, Massimo; Mani, K Radha; Marmot, Michael G; Mattace-Raso, Francesco US; Matullo, Giuseppe; McArdle, Wendy L; McKenzie, Colin A; Meitinger, Thomas; Melander, Olle; Meneton, Pierre; Meschia, James F; Miki, Tetsuro; Milaneschi, Yuri; Mohlke, Karen L; Mooser, Vincent; Morken, Mario A; Morris, Richard W; Mosley, Thomas H; Najjar, Samer; Narisu, Narisu; Newton-Cheh, Christopher; Nguyen, Khanh-Dung Hoang; Nilsson, Peter; Nyberg, Fredrik; O'Donnell, Christopher J; Ogihara, Toshio; Ohkubo, Takayoshi; Okamura, Tomonori; Ong, Rick Twee-Hee; Ongen, Halit; Onland-Moret, N Charlotte; O'Reilly, Paul F; Org, Elin; Orru, Marco; Palmas, Walter; Palmen, Jutta; Palmer, Lyle J; Palmer, Nicholette D; Parker, Alex N; Peden, John F; Peltonen, Leena; Perola, Markus; Pihur, Vasyl; Platou, Carl Geoffrey Parrinder; Plump, Andrew; Prabhakaran, Dorairajan; Psaty, Bruce M; Raffel, Leslie J; Rao, Dabeeru C; Rasheed, Asif; Ricceri, Fulvio; Rice, Kenneth M; Rosengren, Annika; Rotter, Jerome I; Rudock, Megan E; Sober, Siim; Salako, Tunde; Saleheen, Danish; Salomaa, Veikko; Samani, Nilesh J; Schwartz, Steven M; Schwarz, Peter EH; Scott, Laura J; Scott, James; Scuteri, Angelo; Sehmi, Joban S; Seielstad, Mark; Seshadri, Sudha; Sharma, Pankaj; Shaw-Hawkins, Sue; Shi, Gang; Shrine, Nick RG; Sijbrands, Eric JG; Sim, Xueling; Singleton, Andrew; Sjögren, Marketa; Smith, Nicholas L; Artigas, Maria Soler; Spector, Tim D; Staessen, Jan A; Stancakova, Alena; Steinle, Nanette I; Strachan, David P; Stringham, Heather M; Sun, Yan V; Swift, Amy J; Tabara, Yasuharu; Tai, E-Shyong; Talmud, Philippa J; Taylor, Andrew; Terzic, Janos; Thelle, Dag Steinar; Tobin, Martin D; Tomaszewski, Maciej; Tripathy, Vikal; Tuomilehto, Jaakko; Tzoulaki, Ioanna; Uda, Manuela; Ueshima, Hirotsugu; Uiterwaal, Cuno SPM; Umemura, Satoshi; Van Der Harst, Pim; Van Der Schouw, Yvonne T; Van Gilst, Wiek H; Vartiainen, Erkki; Vasan, Ramachandran S; Veldre, Gudrun; Verwoert, Germaine C; Viigimaa, Margus; Vinay, DG; Vineis, Paolo; Voight, Benjamin F; Vollenweider, Peter; Wagenknecht, Lynne E; Wain, Louise V; Wang, Xiaoling; Wang, Thomas J; Wareham, Nicholas J; Watkins, Hugh; Weder, Alan B; Whincup, Peter H; Wiggins, Kerri L; Witteman, Jacqueline CM; Wong, Andrew; Wu, Ying; Yajnik, Chittaranjan S; Yao, Jie; Young, JH; Zelenika, Diana; Zhai, Guangju; Zhang, Weihua; Zhang, Feng; Zhao, Jing Hua; Zhu, Haidong; Zhu, Xiaofeng; Zitting, Paavo; Zukowska-Szczechowska, Ewa; Okada, Yukinori; Wu, Jer-Yuarn; Gu, Dongfeng; Takeuchi, Fumihiko; Takahashi, Atsushi; Maeda, Shiro; Tsunoda, Tatsuhiko; Chen, Peng; Lim, Su-Chi; Wong, Tien-Yin; Liu, Jianjun; Young, Terri L; Aung, Tin; Teo, Yik-Ying; Kim, Young Jin; Kang, Daehee; Chen, Chien-Hsiun; Tsai, Fuu-Jen; Chang, Li-Ching; Fann, S-J Cathy; Mei, Hao; Hixson, James E; Chen, Shufeng; Katsuya, Tomohiro; Isono, Masato; Albrecht, Eva; Yamamoto, Kazuhiko; Kubo, Michiaki; Nakamura, Yusuke; Kamatani, Naoyuki; Kato, Norihiro; He, Jiang; Chen, Yuan-Tsong; Tanaka, Toshihiro; Reilly, Muredach P; Schunkert, Heribert; Assimes, Themistocles L; Hall, Alistair; Hengstenberg, Christian; König, Inke R; Laaksonen, Reijo; McPherson, Ruth; Thompson, John R; Thorsteinsdottir, Unnur; Ziegler, Andreas; Absher, Devin; Chen, Li; Cupples, L Adrienne; Halperin, Eran; Li, Mingyao; Musunuru, Kiran; Preuss, Michael; Schillert, Arne; Thorleifsson, Gudmar; Wells, George A; Holm, Hilma; Roberts, Robert; Stewart, Alexandre FR; Fortmann, Stephen; Go, Alan; Hlatky, Mark; Iribarren, Carlos; Knowles, Joshua; Myers, Richard; Quertermous, Thomas; Sidney, Steven; Risch, Neil; Tang, Hua; Blankenberg, Stefan; Schnabel, Renate; Sinning, Christoph; Lackner, Karl J; Tiret, Laurence; Nicaud, Viviane; Cambien, Francois; Bickel, Christoph; Rupprecht, Hans J; Perret, Claire; Proust, Carole; Munzel, Thomas F; Barbalic, Maja; Chen, Ida Yii-Der; Demissie-Banjaw, Serkalem; Folsom, Aaron; Lumley, Thomas; Marciante, Kristin; Taylor, Kent D; Volcik, Kelly; Gretarsdottir, Solveig; Gulcher, Jeffrey R; Kong, Augustine; Stefansson, Kari; Thorgeirsson, Gudmundur; Andersen, Karl; Fischer, Marcus; Grosshennig, Anika; Linsel-Nitschke, Patrick; Stark, Klaus; Schreiber, Stefan; Aherrahrou, Zouhair; Bruse, Petra; Doering, Angela; Klopp, Norman; Diemert, Patrick; Loley, Christina; Medack, Anja; Nahrstedt, Janja; Peters, Annette; Wagner, Arnika K; Willenborg, Christina; Böhm, Bernhard O; Dobnig, Harald; Grammer, Tanja B; Hoffmann, Michael M; Meinitzer, Andreas; Winkelmann, Bernhard R; Pilz, Stefan; Renner, Wilfried; Scharnagl, Hubert; Stojakovic, Tatjana; Tomaschitz, Andreas; Winkler, Karl; Guiducci, Candace; Burtt, Noel; Gabriel, Stacey B; Dandona, Sonny; Jarinova, Olga; Qu, Liming; Wilensky, Robert; Matthai, William; Hakonarson, Hakon H; Devaney, Joe; Burnett, Mary Susan; Pichard, Augusto D; Kent, Kenneth M; Satler, Lowell; Lindsay, Joseph M; Waksman, Ron; Knouff, Christopher W; Waterworth, Dawn M; Walker, Max C; Epstein, Stephen E; Rader, Daniel J; Nelson, Christopher P; Wright, Benjamin J; Balmforth, Anthony J; Ball, Stephen G; Loehr, Laura R; Rosamond, Wayne D; Benjamin, Emelia; Haritunians, Talin; Couper, David; Murabito, Joanne; Wang, Ying A; Stricker, Bruno H; Chang, Patricia P; Willerson, James T; Felix, Stephan B; Watzinger, Norbert; Aragam, Jayashri; Zweiker, Robert; Lind, Lars; Rodeheffer, Richard J; Greiser, Karin Halina; Deckers, Jaap W; Stritzke, Jan; Ingelsson, Erik; Kullo, Iftikhar; Haerting, Johannes; Reffelmann, Thorsten; Redfield, Margaret M; Werdan, Karl; Mitchell, Gary F; Arnett, Donna K; Gottdiener, John S; Blettner, Maria; Friedrich, Nele; Kovacs, Peter; Wild, Philipp S; Froguel, Philippe; Rettig, Rainer; Mägi, Reedik; Biffar, Reiner; Schmidt, Reinhold; Middelberg, Rita P S; Carroll, Robert J; Penninx, Brenda W; Scott, Rodney J; Katz, Ronit; Sedaghat, Sanaz; Wild, Sarah H; Kardia, Sharon L R; Ulivi, Sheila; Hwang, Shih-Jen; Enroth, Stefan; Kloiber, Stefan; Trompet, Stella; Stengel, Benedicte; Hancock, Stephen J; Turner, Stephen T; Rosas, Sylvia E; Stracke, Sylvia; Harris, Tamara B; Zeller, Tanja; Zemunik, Tatijana; Lehtimäki, Terho; Illig, Thomas; Aspelund, Thor; Nikopensius, Tiit; Esko, Tonu; Tanaka, Toshiko; Gyllensten, Ulf; Völker, Uwe; Emilsson, Valur; Vitart, Veronique; Aalto, Ville; Gudnason, Vilmundur; Chouraki, Vincent; Chen, Wei-Min; Igl, Wilmar; März, Winfried; Koenig, Wolfgang; Lieb, Wolfgang; Loos, Ruth J F; Liu, Yongmei; Snieder, Harold; Pramstaller, Peter P; Parsa, Afshin; O'Connell, Jeffrey R; Susztak, Katalin; Hamet, Pavel; Tremblay, Johanne; De Boer, Ian H; Böger, Carsten A; Goessling, Wolfram; Chasman, Daniel I; Köttgen, Anna; Kao, W H Linda; Fox, Caroline S. (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
    Reduced glomerular filtration rate defines chronic kidney disease and is associated with cardiovascular and all-cause mortality. We conducted a meta-analysis of genome-wide association studies for estimated glomerular ...
  • Genetic background of Cambodian pneumococcal carriage isolates following pneumococcal conjugate vaccine 13 
    Belman, Sophie; Soeng, Sona; Soputhy, Chansovannara; Gladstone, Rebecca Ashley; Hawkins, Paulina A.; Breiman, Robert F.; McGee, Lesley; Bentley, Stephen D.; Lo, Stephanie W.; Turner, Paul (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
    Streptococcus pneumoniae (the pneumococcus) is a leading cause of childhood mortality globally and in Cambodia. It is commensal in the human nasopharynx, occasionally resulting in invasive disease. Monitoring population ...
  • Genetic evolution of invasive emm28 Streptococcus pyogenes strains and significant association with puerperal infections in young women in Finland 
    Gröndahl-Yli-Hannuksela, Kirsi; Beres, Stephen B.; Hyyryläinen, H.-L.; Kallonen, Teemu; Musser, James M.; Vuopio, Jaana (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
    Objectives Streptococcus pyogenes or group A streptococcus (GAS) is a human specific pathogen that annually infects over 700 million individuals. GAS strains of type emm28 are an abundant cause of invasive infections ...
  • Genetic Overlap Between Alzheimer’s Disease and Bipolar Disorder Implicates the MARK2 and VAC14 Genes 
    Drange, Ole Kristian; Smeland, Olav Bjerkehagen; Shadrin, Alexey A.; Finseth, Per Ivar; Witoelar, Aree; Frei, Oleksandr; Psychiatric Genomic Consortium, Bipolar Disorder Working Group; Wang, Yunpeng; Hassani, Sahar; Srdjan, Djurovic; Dale, Anders; Andreassen, Ole Andreas (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
    Background: Alzheimer’s disease (AD) and bipolar disorder (BIP) are complex traits influenced by numerous common genetic variants, most of which remain to be detected. Clinical and epidemiological evidence suggest that AD ...
  • Genetic regulation of liver lipids in a mouse model of insulin resistance and hepatic steatosis 
    Norheim, Frode Amador; Chella Krishnan, Karthickeyan; Bjellaas, Thomas; Vergnes, Laurent; Pan, Calvin; Parks, Brian W.; Meng, Yonghong; Lang, Jennifer M.; Ward, James A; Reue, Karen; Mehrabian, Margarete; Gundersen, Thomas Erik; Péterfy, Miklós; Dalen, Knut Tomas; Drevon, Christian A; Hui, Simon T.; Lusis, Aldons J.; Seldin, Marcus M. (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
    To elucidate the contributions of specific lipid species to metabolic traits, we integrated global hepatic lipid data with other omics measures and genetic data from a cohort of about 100 diverse inbred strains of mice fed ...
  • Genetic regulation of S3-12 : S3-12 is a novel PPARalpha target gene in muscle cells 
    Berg, Ole (Master thesis / Masteroppgave, 2008)
    Summary Excess bodyweight are one of the major global health problems in the world today. In recent years, genetics are demonstrated to play an important role in the development of excess bodyweight, which has led to a ...
  • Genetic Sharing with Cardiovascular Disease Risk Factors and Diabetes Reveals Novel Bone Mineral Density Loci 
    Reppe, Sjur; Wang, Yunpeng; Thompson, WK; McEvoy, LK; Schork, AJ; Zuber, Verena; LeBlanc, Marissa; Bettella, Franscesco; Mills, Ian Geoffrey; Desikan, Rahul S.; Djurovic, Srdjan; Gautvik, Kaare M; Dale, AM; Andreassen, Ole Andreas; GEFOS, Consortium (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)
    Bone Mineral Density (BMD) is a highly heritable trait, but genome-wide association studies have identified few genetic risk factors. Epidemiological studies suggest associations between BMD and several traits and diseases, ...
  • Genetic testing is essential for initiating statin therapy in children with familial hypercholesterolemia: Examples from Scandinavia 
    Svendsen, Karianne; Langslet, Gisle; Krogh, Henriette Walaas; Brinck, Jonas; Stenehjem, Jo S.; Holven, Kirsten Bjørklund; Bogsrud, Martin P; Retterstøl, Kjetil (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
    Background and aims In familial hypercholesterolemia (FH), statin treatment should be considered from 8 to 10 years of age, but the prevalence of statin use among children is not known. Methods Statin use (2008–2018) ...
  • Genetics of Familial Hypercholesterolemia: New Insight. 
    vourio, Alpo; Ramaswami, Uma; Holven, Kirsten Bjørklund (Journal article / Tidsskriftartikkel / PublishedVersion, 2021)
  • Genetics of the thrombomodulin-endothelial cell protein C receptor system and the risk of early-onset ischemic stroke. 
    Cole, John W.; Kanse, Sandip; Authors, Other; Mitchell, Braxton (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
    Background and purpose Polymorphisms in coagulation genes have been associated with early-onset ischemic stroke. Here we pursue an a priori hypothesis that genetic variation in the endothelial-based receptors of the ...
  • Genetics, environmental stress, and amino acid supplementation affect lactational performance via mTOR signaling pathway in bovine mammary epithelial cells 
    Li, Bin; Khan, Muhammad Zahoor; Khan, Ibrar Muhammad; Ullah, Qudrat; Cisang, Zhuo-Ma; Zhang, Nan; Wu, Dan; Huang, Bingjian; Ma, Yulin; Khan, Adnan; Jiang, Nan; Zahoor, Muhammad (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
    Mammary glands are known for their ability to convert nutrients present in the blood into milk contents. In cows, milk synthesis and the proliferation of cow mammary epithelial cells (CMECs) are regulated by various factors, ...