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dc.date.accessioned2013-03-12T08:10:16Z
dc.date.available2013-03-12T08:10:16Z
dc.date.issued2003en_US
dc.date.submitted2003-09-17en_US
dc.identifier.citationNesvold, Håvard. Design of a DNA chip for detection of unknown genetically modified organisms (GMOs). Hovedoppgave, University of Oslo, 2003en_US
dc.identifier.urihttp://hdl.handle.net/10852/8961
dc.description.abstractKnowing the extent and nature of genetically modified (GM) ingredients in food products has become increasingly important for food exporters, importers, retailers and consumers. In this thesis a model for detecting unknown genetically modified organisms (GMOs) by utilization of a high-density synthetic oligonucleotide array (DNA chip) is presented. Biological and combinatorial reduction rules are applied on a set of probes containing all possible sequences of a uniform length n, creating probes which should be fitted on a DNA chip for unknown GMO detection. Reduction rules are defined which eliminate probes that are poor hybridizers, unlikely to be complementary to the modified sequence or which may give rise to false positive hybridization signals. A data structure for handling the relatively large probe sets studied in this thesis is found and suitable algorithms and methods for performing the various reductions devised. The model is finally tested theoretically on seven artificially created genetically modified Arabidopsis thaliana specimens.nor
dc.language.isoengen_US
dc.titleDesign of a DNA chip for detection of unknown genetically modified organisms (GMOs)en_US
dc.typeMaster thesisen_US
dc.date.updated2003-10-07en_US
dc.creator.authorNesvold, Håvarden_US
dc.subject.nsiVDP::420en_US
dc.identifier.bibliographiccitationinfo:ofi/fmt:kev:mtx:ctx&ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&rft.au=Nesvold, Håvard&rft.title=Design of a DNA chip for detection of unknown genetically modified organisms (GMOs)&rft.inst=University of Oslo&rft.date=2003&rft.degree=Hovedoppgaveen_US
dc.identifier.urnURN:NBN:no-6884en_US
dc.type.documentHovedoppgaveen_US
dc.identifier.duo13235en_US
dc.contributor.supervisorAnja Bråthen Kristoffersen, Knut Berdal, Arne Holst-Jensenen_US
dc.identifier.bibsys031386148en_US


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