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dc.date.accessioned2020-09-25T18:26:41Z
dc.date.available2020-09-25T18:26:41Z
dc.date.created2020-09-22T11:04:41Z
dc.date.issued2020
dc.identifier.citationHovey, Daniel Martens, Louise Laeng, Bruno Leknes, Siri Westberg, Lars . The effect of intranasal oxytocin on visual processing and salience of human faces. Translational Psychiatry. 2020, 10(318), 1-9
dc.identifier.urihttp://hdl.handle.net/10852/79978
dc.description.abstractAbstract The mechanisms underlying the role of oxytocin (OT) as a regulator of social behavior in mammals are only partly understood. Recently, it has been proposed that OT increases the salience of social stimuli. We carried out a randomized, double-blind, cross-over study of the effects of OT on binocular rivalry, a visual phenomenon underpinned by the interplay of excitation and inhibition in the cortex. A final sample of 45 participants viewed images of social stimuli (faces with different emotional expressions) and non-social stimuli (houses and Gabor patches). We demonstrate a robust effect that intranasal OT increases the salience of human faces in binocular rivalry, such that dominance durations of faces are longer—this effect is not modulated by the facial expression. We tentatively show that OT treatment increases dominance durations for non-social stimuli. Our results lend support to the social salience hypothesis of OT, and in addition offer provisional support for the role of OT in influencing excitation-inhibition balance in the brain.
dc.languageEN
dc.rightsAttribution 4.0 International
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.titleThe effect of intranasal oxytocin on visual processing and salience of human faces
dc.typeJournal article
dc.creator.authorHovey, Daniel
dc.creator.authorMartens, Louise
dc.creator.authorLaeng, Bruno
dc.creator.authorLeknes, Siri
dc.creator.authorWestberg, Lars
cristin.unitcode185,17,5,0
cristin.unitnamePsykologisk institutt
cristin.ispublishedtrue
cristin.fulltextoriginal
cristin.qualitycode1
dc.identifier.cristin1832016
dc.identifier.bibliographiccitationinfo:ofi/fmt:kev:mtx:ctx&ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Translational Psychiatry&rft.volume=10&rft.spage=1&rft.date=2020
dc.identifier.jtitleTranslational Psychiatry
dc.identifier.volume10
dc.identifier.issue1
dc.identifier.doihttps://doi.org/10.1038/s41398-020-00991-3
dc.identifier.urnURN:NBN:no-83074
dc.type.documentTidsskriftartikkel
dc.type.peerreviewedPeer reviewed
dc.source.issn2158-3188
dc.identifier.fulltextFulltext https://www.duo.uio.no/bitstream/handle/10852/79978/2/Hovey%2BMartens%2BLaeng%2BLeknes%2B%2526%2BWestberg%2B%25282020%2529%2BThe%2Beffect%2Bof%2Bintranasal%2Boxytocin%2Bon%2Bvisual%2Bprocessing%2Band%2Bsalience%2Bof%2Bhuman%2Bfaces.pdf
dc.type.versionPublishedVersion
cristin.articleid318
dc.relation.projectNFR/262762


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