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dc.date.accessioned2020-09-24T17:51:43Z
dc.date.available2020-09-24T17:51:43Z
dc.date.created2020-09-04T10:50:35Z
dc.date.issued2020
dc.identifier.citationSeljetun, Kristin Opdal Sandvik, Morten Vindenes, Vigdis Eliassen, Elin Øiestad, Elisabeth Leere Madslien, Knut Ivar Engesæter Moe, Lars . Comparison of anticoagulant rodenticide concentrations in liver and feces from apparently healthy red foxes. Journal of Veterinary Diagnostic Investigation. 2020, 32(4), 560-564
dc.identifier.urihttp://hdl.handle.net/10852/79943
dc.description.abstractExposure of wildlife and domestic animals to anticoagulant rodenticides (ARs) is a worldwide concern, but few methods exist to determine residue levels in live animals. Traditional liver detection methods preclude determining exposure in live wildlife. To determine the value of assessing AR exposure by fecal analysis, we compared fecal and liver residues of ARs in the same animals. We collected liver and fecal samples from 40 apparently healthy red foxes (Vulpes vulpes) potentially exposed to ARs, and quantified brodifacoum, bromadiolone, coumatetralyl, difenacoum, difethialone, and flocoumafen residues by liquid chromatography–tandem mass spectrometry. Residues of ARs were detected in 53% of the fecal samples and 83% of the liver samples. We found good concordance between AR residues in feces and liver for coumatetralyl, difenacoum, and difethialone. Bromadiolone occurred in significantly greater frequency in livers compared to feces, but no significant difference in concentration between feces and liver in individual foxes could be detected. Brodifacoum displayed a significant difference in concentration and occurrence of positive samples between liver and feces. Our findings demonstrate that fecal analysis of ARs provides a feasible and valuable non-lethal means of determine AR exposure in live wildlife.
dc.languageEN
dc.titleComparison of anticoagulant rodenticide concentrations in liver and feces from apparently healthy red foxes
dc.typeJournal article
dc.creator.authorSeljetun, Kristin Opdal
dc.creator.authorSandvik, Morten
dc.creator.authorVindenes, Vigdis
dc.creator.authorEliassen, Elin
dc.creator.authorØiestad, Elisabeth Leere
dc.creator.authorMadslien, Knut Ivar Engesæter
dc.creator.authorMoe, Lars
cristin.unitcode185,53,18,18
cristin.unitnameAvdeling for rettsmedisinske fag
cristin.ispublishedtrue
cristin.fulltextpostprint
cristin.qualitycode1
dc.identifier.cristin1827317
dc.identifier.bibliographiccitationinfo:ofi/fmt:kev:mtx:ctx&ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Journal of Veterinary Diagnostic Investigation&rft.volume=32&rft.spage=560&rft.date=2020
dc.identifier.jtitleJournal of Veterinary Diagnostic Investigation
dc.identifier.volume32
dc.identifier.issue4
dc.identifier.startpage560
dc.identifier.endpage564
dc.identifier.doihttps://doi.org/10.1177/1040638720927365
dc.identifier.urnURN:NBN:no-83047
dc.type.documentTidsskriftartikkel
dc.type.peerreviewedPeer reviewed
dc.source.issn1040-6387
dc.identifier.fulltextFulltext https://www.duo.uio.no/bitstream/handle/10852/79943/2/Postnr%2B1827317_Seljetun_ARF_postprint.pdf
dc.type.versionAcceptedVersion


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