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Relationships between depressive symptoms and panic disorder symptoms during guided internet-delivered cognitive behavior therapy for panic disorder

Walderhaug, Eirik Paulsen; Gjestad, Rolf; Egeland, Jens; Havik, Odd E.; Nordgreen, Tine
Journal article; AcceptedVersion; Peer reviewed
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walderhaug2019.pdf (571.7Kb)
Year
2019
Permanent link
http://urn.nb.no/URN:NBN:no-77861

CRIStin
1714106

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  • Psykologisk institutt [2998]
  • CRIStin høstingsarkiv [17102]
Original version
Nordic Journal of Psychiatry. 2019, 73 (7), 417-424, DOI: https://doi.org/10.1080/08039488.2019.1646803
Abstract
Aims: The current study explore the relationship between the trajectories of primary panic disorder symptoms and secondary depressive symptoms during guided internet-delivered cognitive behaviour therapy for panic disorder.

Materials and methods: The patients (N=143) were recruited from an ongoing effectiveness study in secondary mental health outpatient services in Norway. Weekly self-reported primary panic disorder symptoms and secondary depressive symptoms were analysed.

Results: primary panic disorder symptoms and secondary depressive symptoms improved significantly during the course of treatment, and at six months follow-up. Parallel process latent growth curve modelling showed that the trajectory of depressive symptoms and trajectory of panic disorder symptoms were significantly related. A supplementary analysis with cross-lagged panel modelling showed that (1) pre-treatment depressive symptoms predicted a positive effect of panic disorder symptoms early in treatment; (2) high early treatment panic disorder symptoms predicted low depressive symptoms at post-treatment.

Conclusions: Guided ICBT for panic disorder is effective for both primary panic disorder symptoms and secondary depressive symptoms. Patients with high pre-treatment secondary depressive symptoms may constitute a vulnerable subgroup. A high level of panic disorder symptoms early in treatment seems beneficiary for depressive symptoms outcome. A time-dependent model may be necessary to describe the relationship between PAD symptoms and depressive symptoms during the course of treatment.
 
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