Long non-coding RNAs (lncRNAs) and cardiovascular disease (CVD)

Abstract

Long non-coding RNAs (lncRNAs) have broken into the limelight in the wake of advances in sequencing technologies in recent years. Progression in uncovering functions and properties of these transcripts, have provided initial insights into their roles in both physiological and pathological states. While they have been linked to the development of cancers, association in other disease groups such as cardiovascular diseases (CVDs) has also been found. This review aims to shed light on mechanisms and functions of lncRNA, their role in CVD, and explore their potential use in diagnostic and therapeutic strategies.