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dc.date.accessioned2019-06-03T05:51:53Z
dc.date.available2019-08-13T22:46:58Z
dc.date.created2018-09-26T15:31:28Z
dc.date.issued2018
dc.identifier.citationHabberstad, Ragnhild H Hjermstad, Marianne Jensen Brunelli, Cinzia Kaasa, Stein Bennett, Michael I Pardon, Koen Klepstad, Pål . Which factors can aid clinicians to identify a risk of pain during the following month in patients with bone metastases? A longitudinal analyses. Supportive Care in Cancer. 2018, 1-9
dc.identifier.urihttp://hdl.handle.net/10852/68195
dc.description.abstractPurpose: Explore clinical factors associated with higher pain intensity and future pain in patients with bone metastases to identify patients who can benefit from closer follow-up or pain-modifying interventions. Methods: This is a secondary analysis of 606 patients with bone metastases included in a multicenter longitudinal study. The dependent variables were “average pain” and “worst pain” in the last 24 h (0–10 NRS). Twenty independent variables with potential association to pain intensity were selected based on previous literature. Cross-sectional analyses were performed with multiple linear regression to explore factors associated with pain intensity at baseline. Longitudinal data were analyzed with a generalized equation models to explore current factors associated with pain intensity at the next visit in 1 month. Results: Current pain intensity (p < 0.001), sleep disturbances (p 0.01 and 0.006), drowsiness (p 0.003 and 0.033) and male gender (p 0.045 and 0.001) were associated with higher average and worst pain intensity in 1 month. In addition, breakthrough pain was related to higher worst pain intensity (p 0.003) in 1 month. The same variables were also associated with higher average pain intensity at baseline. Conclusion: Higher current pain intensity, sleep disturbances, drowsiness, male gender, and breakthrough pain are factors associated with higher pain intensity in patients with bone metastases at the next follow-up in 1 month. These factors should be assessed in clinical practice and may aid clinicians in identifying patients that can benefit from closer follow-up or interventions to prevent lack of future pain control.en_US
dc.languageEN
dc.titleWhich factors can aid clinicians to identify a risk of pain during the following month in patients with bone metastases? A longitudinal analysesen_US
dc.typeJournal articleen_US
dc.creator.authorHabberstad, Ragnhild H
dc.creator.authorHjermstad, Marianne Jensen
dc.creator.authorBrunelli, Cinzia
dc.creator.authorKaasa, Stein
dc.creator.authorBennett, Michael I
dc.creator.authorPardon, Koen
dc.creator.authorKlepstad, Pål
cristin.unitcode185,53,49,0
cristin.unitnameKreftklinikken
cristin.ispublishedtrue
cristin.fulltextpostprint
cristin.qualitycode1
dc.identifier.cristin1614206
dc.identifier.bibliographiccitationinfo:ofi/fmt:kev:mtx:ctx&ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Supportive Care in Cancer&rft.volume=&rft.spage=1&rft.date=2018
dc.identifier.jtitleSupportive Care in Cancer
dc.identifier.startpage1
dc.identifier.endpage9
dc.identifier.doihttp://dx.doi.org/10.1007/s00520-018-4405-9
dc.identifier.urnURN:NBN:no-71356
dc.type.documentTidsskriftartikkelen_US
dc.type.peerreviewedPeer reviewed
dc.source.issn0941-4355
dc.identifier.fulltextFulltext https://www.duo.uio.no/bitstream/handle/10852/68195/4/Habberstad_Revised_manuscript2.pdf
dc.type.versionAcceptedVersion


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