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dc.date.accessioned2019-03-05T11:35:23Z
dc.date.available2019-08-11T22:46:35Z
dc.date.created2018-08-23T15:22:50Z
dc.date.issued2018
dc.identifier.citationKorsmo-Haugen, Henny-Kristine Brurberg, Kjetil Gundro Mann, Jim I Aas, Anne-Marie . Carbohydrate quantity in the dietary management of type 2 diabetes: A systematic review and meta-analysis. Diabetes, obesity and metabolism. 2018, 21, 15-27
dc.identifier.urihttp://hdl.handle.net/10852/67047
dc.description.abstractAims: This systematic review and meta‐analysis (registration number: CRD42013005825) compares the effects of low carbohydrate diets (LCDs) on body weight, glycaemic control, lipid profile and blood pressure with the effects of higher carbohydrate diets (HCDs) in adults with type 2 diabetes. Methods: MEDLINE, EMBASE, CENTRAL, CINAHL, Food Science Source and SweMed+ databases were systematically searched to identify randomized controlled trials (duration ≥3 months) investigating the effects of an LCD compared to an HCD in the management of type 2 diabetes. Data were extracted and pooled using a random effects model and were expressed as mean differences and risk ratio. Subgroup analyses were undertaken to examine the effects of duration of intervention, extent of carbohydrate restriction and risk of bias. The certainty of evidence was assessed using GRADE. Results: Of the 1589 studies identified, 23, including 2178 participants, met inclusion criteria. Reductions were slightly greater with LCDs than with HCDs for HbA1c (−1.0 mmol/mol; CI, −1.9, −0.1 [−0.09%; CI, −0.17, −0.01]) and for triglycerides (−0.13 mmol/L; CI, −0.24, −0.02). Changes in weight, HDL‐ and LDL‐cholesterol, total cholesterol and blood pressure did not differ significantly between groups. Subgroup analyses suggested that the difference in HbA1c was evident only in studies with a duration of ≤6 months and with a high risk of bias. Conclusions: The proportion of daily energy provided by carbohydrate intake is not an important determinant of response to dietary management, especially when considering longer term trials. A range of dietary patterns, including those traditional in Mediterranean countries, seems suitable for translating nutritional recommendations for individuals with diabetes into practical advice.en_US
dc.languageEN
dc.titleCarbohydrate quantity in the dietary management of type 2 diabetes: A systematic review and meta-analysisen_US
dc.typeJournal articleen_US
dc.creator.authorKorsmo-Haugen, Henny-Kristine
dc.creator.authorBrurberg, Kjetil Gundro
dc.creator.authorMann, Jim I
dc.creator.authorAas, Anne-Marie
cristin.unitcode185,53,11,21
cristin.unitnameAvdeling for klinisk service
cristin.ispublishedtrue
cristin.fulltextpostprint
cristin.qualitycode1
dc.identifier.cristin1604103
dc.identifier.bibliographiccitationinfo:ofi/fmt:kev:mtx:ctx&ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Diabetes, obesity and metabolism&rft.volume=21&rft.spage=15&rft.date=2018
dc.identifier.jtitleDiabetes, obesity and metabolism
dc.identifier.volume21
dc.identifier.startpage15
dc.identifier.endpage27
dc.identifier.doihttp://dx.doi.org/10.1111/dom.13499
dc.identifier.urnURN:NBN:no-70235
dc.type.documentTidsskriftartikkelen_US
dc.type.peerreviewedPeer reviewed
dc.source.issn1462-8902
dc.identifier.fulltextFulltext https://www.duo.uio.no/bitstream/handle/10852/67047/6/DOM%2B2nd%2Bresubmission%2Barticle.pdf
dc.identifier.fulltextFulltext https://www.duo.uio.no/bitstream/handle/10852/67047/7/Supplementary_material.pdf
dc.type.versionAcceptedVersion


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