Search
Now showing items 1-31 of 31
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
Abstract Cortical microstructure is influenced by circadian rhythm and sleep deprivation, yet the precise underpinnings of these effects remain unclear. The ratio between T 1 -weighted and T 2 -weighted magnetic resonance ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Emotional disorders commonly emerge in adolescence, a period characterized by changes in emotion-related processes. Thus, the ability to regulate emotions is crucial for well-being and adaptive social functioning during ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Background To test the hypothesis that worse self-reported sleep relates to memory decay and reduced hippocampal integrity as indexed by increased intra-hippocampal water diffusion, and that the relations are stronger in ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Abstract Cortical thinning occurs throughout the entire life and extends to late-life neurodegeneration, yet the neurobiological substrates are poorly understood. Here, we used a virtual-histology technique and gene ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Abstract
It has been suggested that specific forms of cognition in older age rely largely on late-life specific mechanisms. Here instead, we tested using task-fMRI (n = 540, age 6–82 years) whether the functional ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
Prosocial behavior, or voluntary actions that intentionally benefit others, relate to desirable developmental outcomes such as peer acceptance, while lack of prosocial behavior has been associated with several neurodevelopmental ...
(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2018)
(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2018)
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
Seminal human brain histology work has demonstrated developmental waves of myelination. Here, using a micro-structural magnetic resonance imaging (MRI) marker linked to myelin, we studied fine-grained age differences to ...
(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2018)
How personality traits relate to structural brain changes in development is an important but understudied question. In this study, cortical thickness (CT) and surface area (SA), estimated using magnetic resonance imaging ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
Working memory capacity is pivotal for a broad specter of cognitive tasks and develops throughout childhood. This must in part rely on development of neural connections and white matter microstructure maturation, but there ...
(Journal article / Tidsskriftartikkel / SubmittedVersion; Peer reviewed, 2017)
Age differences in human brain plasticity are assumed, but have not been systematically investigated. In this longitudinal study, we investigated changes in white matter (WM) microstructure in response to memory training ...
(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2016)
Extensive efforts are devoted to understand the functional (FC) and structural connections (SC) of the brain. FC is usually measured by functional magnetic resonance imaging (fMRI), and conceptualized as degree of synchronicity ...
(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2016)
Higher order speeded cognitive abilities depend on efficient coordination of activity across the brain, rendering them vulnerable to age reductions in structural and functional brain connectivity. The concept of “disconnected ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
Age-related differences in white matter (WM) integrity are substantial, but it is unknown whether between-subject variability in WM integrity influences the capacity for cognitive improvement. We investigated the effects ...
(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2016)
At a large scale, the human brain is organized into modules of interconnected regions, some of which play opposing roles in supporting cognition. In particular, the Default-Mode Network (DMN) has been linked to operations ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
The purpose of the present study was to detail the childhood developmental course of different white matter (WM) characteristics. In a longitudinal diffusion tensor imaging (DTI) study of 159 healthy children between 4 and ...
(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2016)
Highly myelinated cortical regions seem to develop early and are more robust to age-related decline. By use of different magnetic resonance imaging (MRI) measures such as contrast between T1- and T2-weighted MRI scans ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)
We continuously encounter and process novel events in the surrounding world, but only some episodes will leave detailed memory traces that can be recollected after weeks and months. Here, our aim was to monitor brain ...
(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2015)
Alzheimer's disease (AD) is regarded a human-specific condition, and it has been suggested that brain regions highly expanded in humans compared with other primates are selectively targeted. We calculated shared and unique ...
(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2015)
Myelin content of the cerebral cortex likely impacts cognitive functioning, but this notion has scarcely been investigated in vivo in humans. Here we tested for a relationship between intracortical myelin and a direct ...
(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2015)
In this perspective paper, we examine possible premises of plasticity in the neural substrates underlying cognitive change. We take the special role of the medial temporal lobe as an anchoring point, but also investigate ...
(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2015)
Cortical surface area has tremendously expanded during human evolution, and similar patterns of cortical expansion have been observed during childhood development. An intriguing hypothesis is that the high-expanding cortical ...
(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2015)
There is a growing realization that early life influences have lasting impact on brain function and structure. Recent research has demon- strated that genetic relationships in adults can be used to parcellate the cortex ...
(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2015)
A major task of contemporary cognitive neuroscience of aging is to explain why episodic memory declines. Change in resting-state functional connectivity (rsFC) could be a mechanism accounting for reduced function. We ...
(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2015)
Episodic memories are established and maintained by close interplay between hippocampus and other cortical regions, but degradation of a fronto-striatal network has been suggested to be a driving force of memory decline ...
(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2014)
The hippocampus is an anatomically and functionally heterogeneous structure, but longitudinal studies of its regional development are scarce and it is not known whether protracted maturation of the hippocampus in adolescence ...
(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2014)
The hippocampus supports several important cognitive functions known to undergo substantial development during childhood and adolescence, for example, encoding and consolidation of vivid personal memories. However, diverging ...
(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2013)
Age-related changes in brain structure result from a complex interplay among various neurobiological processes, which may contribute to more complex trajectories than what can be described by simple linear or quadratic ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2013)
Parallels between patterns of brain maturation and cognitive development have been observed repeatedly, but studies directly testing the relationships between improvements in specific cognitive functions and structural ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2013)
Cerebral myelin maturation and aging-related degradation constitute fundamental features of human brain integrity and functioning. Although mostly studied in the white matter, the cerebral cortex contains significant amounts ...