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Development of efficient (radio)fluorination reactions of hypervalent iodinanes for synthesising electron rich [18F]-labelled fluoroarenes for imaging of N-methyl-D-aspartate receptors

Jakobsson, Jimmy Erik
Doctoral thesis
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PhD-Jakobsson-2018.pdf (1.846Mb)
Year
2018
Permanent link
http://urn.nb.no/URN:NBN:no-67898

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  • Kjemisk institutt [843]
Abstract
No abstract.
List of papers
Article I: Jakobsson, J. E.; Grønnevik, G.; Riss, P. J., Organocatalyst-assisted Ar-18F bond formation: a universal procedure for direct aromatic radiofluorination. Chem Commun (Camb) 2017, 53 (96), 12906-12909. DOI: 10.1039/c7cc07211b. The paper is not available in DUO due to publisher restrictions. The published version is available at: https://doi.org/10.1039/c7cc07211b
Article II: Jakobsson J. E.; Riss, P. J., Transition metal free, late-stage, regiospecific, aromatic fluorination on preparative scale using KF/Crypt-222 complex. RSC Advances 2018, 8, 21288-21291. DOI: 10.1039/c8ra03757d. The article is included in the thesis. Also available at https://doi.org/10.1039/c8ra03757d
Article III: Jakobss J. E.; Grønnevik, G.; Rafique, W.; Hartvig K.; Riss, P. J., Formamide as an unconventional amine protecting group for PET radiochemistry. Eur. J. Org. Chem. 2018, 3701-3704. DOI: 10.1002/ejoc.201800554. The paper is not available in DUO due to publisher restrictions. The published version is available at: https://doi.org/10.1002/ejoc.201800554
Article IV: Jakobsson, J. E.; Gourni, E.; Shivashankar K.; Brito, B. and Riss, P. J., Synthesis and in vivo characterization in rodent brain of the subtype selective NR2B NMDA receptor ligand [11C]Ro 04-5595 as a radio-tracer for positron emission tomography. Submitted. To be published. The paper is not available in DUO awaiting publishing.
 
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