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dc.date.accessioned2018-10-11T10:33:05Z
dc.date.available2018-10-11T10:33:05Z
dc.date.created2018-02-01T16:04:44Z
dc.date.issued2017
dc.identifier.citationCheneby, J Gheorghe, Marius Artufel, M Mathelier, Anthony Ballester, B . ReMap 2018: an updated atlas of regulatory regions from an integrative analysis of DNA-binding ChIP-seq experiments. Nucleic Acids Research. 2017, 46(D1), D267-D275
dc.identifier.urihttp://hdl.handle.net/10852/65125
dc.description.abstractWith this latest release of ReMap (http://remap.cisreg.eu), we present a unique collection of regulatory regions in human, as a result of a large-scale integrative analysis of ChIP-seq experiments for hundreds of transcriptional regulators (TRs) such as transcription factors, transcriptional co-activators and chromatin regulators. In 2015, we introduced the ReMap database to capture the genome regulatory space by integrating public ChIP-seq datasets, covering 237 TRs across 13 million (M) peaks. In this release, we have extended this catalog to constitute a unique collection of regulatory regions. Specifically, we have collected, analyzed and retained after quality control a total of 2829 ChIP-seq datasets available from public sources, covering a total of 485 TRs with a catalog of 80M peaks. Additionally, the updated database includes new search features for TR names as well as aliases, including cell line names and the ability to navigate the data directly within genome browsers via public track hubs. Finally, full access to this catalog is available online together with a TR binding enrichment analysis tool. ReMap 2018 provides a significant update of the ReMap database, providing an in depth view of the complexity of the regulatory landscape in human.en_US
dc.languageEN
dc.publisherOxford University Press
dc.relation.ispartofGheorghe, Marius (2020) Integrative approaches to study TF-DNA interactions. Doctoral thesis http://hdl.handle.net/10852/75931
dc.relation.urihttp://hdl.handle.net/10852/75931
dc.rightsAttribution-NonCommercial 4.0 International
dc.rights.urihttps://creativecommons.org/licenses/by-nc/4.0/
dc.titleReMap 2018: an updated atlas of regulatory regions from an integrative analysis of DNA-binding ChIP-seq experimentsen_US
dc.typeJournal articleen_US
dc.creator.authorCheneby, J
dc.creator.authorGheorghe, Marius
dc.creator.authorArtufel, M
dc.creator.authorMathelier, Anthony
dc.creator.authorBallester, B
cristin.unitcode185,57,12,0
cristin.unitnameAnthony Mathelier Group - Computational Biology & Gene Regulation
cristin.ispublishedtrue
cristin.fulltextoriginal
cristin.qualitycode2
dc.identifier.cristin1560873
dc.identifier.bibliographiccitationinfo:ofi/fmt:kev:mtx:ctx&ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Nucleic Acids Research&rft.volume=46&rft.spage=D267&rft.date=2017
dc.identifier.jtitleNucleic Acids Research
dc.identifier.volume46
dc.identifier.issueD1
dc.identifier.startpageD267
dc.identifier.endpageD275
dc.identifier.doihttp://dx.doi.org/10.1093/nar/gkx1092
dc.identifier.urnURN:NBN:no-67655
dc.type.documentTidsskriftartikkelen_US
dc.type.peerreviewedPeer reviewed
dc.source.issn0305-1048
dc.identifier.fulltextFulltext https://www.duo.uio.no/bitstream/handle/10852/65125/2/Cheneby_etal_NAR.pdf
dc.type.versionPublishedVersion
dc.relation.projectNFR/144182


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