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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
The deviation between chronological age and age predicted using brain MRI is a putative marker of overall brain health. Age prediction based on structural MRI data shows high accuracy in common brain disorders. However, ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Brainstem regions support vital bodily functions, yet their genetic architectures and involvement in common brain disorders remain understudied. Here, using imaging-genetics data from a discovery sample of 27,034 individuals, ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Cognitive impairments are considered core features in schizophrenia and other psychotic disorders. Cognitive impairments are, to a lesser degree, also documented in healthy first-degree relatives. Although recent studies ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
The hippocampus consists of anatomically and functionally distinct subfields that may be differentially involved in the pathophysiology of bipolar disorder (BD). Here we, the Enhancing NeuroImaging Genetics through ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Introduction: Approximately 10% of patients with psychotic disorders receive the diagnosis “Psychotic disorder not otherwise specified” (PNOS). However, there is a lack of knowledge about the clinical presentations captured ...
(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2020)
Lack of clinical insight in patients with schizophrenia is an obstacle to optimal treatment. Social cognition is one of several variables central to insight deficits in schizophrenia. The aim of this study was to investigate ...
Childhood Trauma Is Nominally Associated With Elevated Cortisol Metabolism in Severe Mental Disorder
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Objective: Individuals exposed to childhood trauma display longstanding modifications of the Hypothalamic–Pituitary–Adrenal (HPA) axis, as well as cognitive impairments. Schizophrenia spectrum disorder (SZ) and bipolar ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Abstract Cortical thickness, surface area and volumes vary with age and cognitive function, and in neurological and psychiatric diseases. Here we report heritability, genetic correlations and genome-wide associations of ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Background.
Despite apparent clinical remission, individuals with psychotic disorders often experience significant impairments across functional domains. Thus, there is a need to search beyond management of core symptoms ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Schizophrenia (SCZ) is associated with an increased risk of violence compared to the general population. Previous studies have indicated smaller hippocampal and amygdala volumes in violent than non-violent psychotic patients. ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Background
The Sense of Coherence (SOC) theory gives a possible explanation of how people can experience subjective good health despite severe illness. Basic self-disturbances (BSDs) are subtle non-psychotic disturbances ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
To investigate whether changes in serum lipids are associated with cognitive performance in first episode psychosis (FEP) patients during their first year of antipsychotic drug treatment. One hundred and thirty-two ...