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GWAS meta-analysis reveals novel loci and genetic correlates for general cognitive function: a report form the COGENT consortium
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
The complex nature of human cognition has resulted in cognitive genomics lagging behind many other fields in terms of gene discovery using genome-wide association study (GWAS) methods. In an attempt to overcome these ...
Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
General cognitive function is a prominent and relatively stable human trait that is associated with many important life outcomes. We combine cognitive and genetic data from the CHARGE and COGENT consortia, and UK Biobank ...
Pleiotropic meta-analysis of cognition, education, and schizophrenia differentiates roles of early neurodevelopmental and adult synaptic pathways
(Journal article / Tidsskriftartikkel / SubmittedVersion, 2019)
Susceptibility to schizophrenia is inversely correlated with general cognitive ability at both the phenotypic and the genetic level. Paradoxically, a modest but consistent positive genetic correlation has been reported ...