This thesis looks at opportunities and challenges when thinking anthropology and social media. With a focus on Twitter and anthropological ideas, it attempts to consider a broad spectrum of different aspects surrounding Twitter in an anthropological sense, and anthropology in light of Twitter. It attempts to connect Twitter and newer social media to basic anthropological ideas. While it is no deep dive into one single aspect, the thesis attempts to cover several. This ranges from technical solutions regarding data gathering, to ethical questions regarding bots or trolls. Viewing these new solutions, to perhaps familiar challenges, it tries to answer if new fields do indeed require new tools.