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dc.date.accessioned2018-08-17T07:25:11Z
dc.date.available2018-08-17T07:25:11Z
dc.date.created2018-07-23T10:35:23Z
dc.date.issued2018
dc.identifier.citationBrunetti, Marta Gorunova, Ludmila Davidson, Ben Heim, Sverre Panagopoulos, Ioannis Micci, Francesca . Identification of an EPC2-PHF1 fusion transcript in low-grade endometrial stromal sarcoma. OncoTarget. 2018, 9(27), 19203-19208
dc.identifier.urihttp://hdl.handle.net/10852/63025
dc.description.abstractRecurrent chromosomal translocations leading to gene fusion formation have been described in uterine sarcomas, including low-grade endometrial stromal sarcoma (LG-ESS). Involvement of the PHF1 gene in chromosomal rearrangements targeting band 6p21 has been found in LG-ESS with different partners from JAZF1 mapping in 7p15, to EPC1 from 10p11, MEAF6 from 1p34, and BRD8 from 5q31. In the present study, RNA sequencing of a LG-ESS showed a novel recombination of PHF1 with the Enhancer of Polycomb homolog 2 (EPC2). RT-PCR followed by Sanger sequencing and FISH analysis confirmed the EPC2-PHF1 fusion transcript.en_US
dc.languageEN
dc.language.isoenen_US
dc.publisherImpact Journals LLC
dc.rightsAttribution 3.0 Unported
dc.rights.urihttps://creativecommons.org/licenses/by/3.0/
dc.titleIdentification of an EPC2-PHF1 fusion transcript in low-grade endometrial stromal sarcomaen_US
dc.title.alternativeENEngelskEnglishIdentification of an EPC2-PHF1 fusion transcript in low-grade endometrial stromal sarcoma
dc.typeJournal articleen_US
dc.creator.authorBrunetti, Marta
dc.creator.authorGorunova, Ludmila
dc.creator.authorDavidson, Ben
dc.creator.authorHeim, Sverre
dc.creator.authorPanagopoulos, Ioannis
dc.creator.authorMicci, Francesca
cristin.unitcode185,53,18,13
cristin.unitnameAvdeling for patologi
cristin.ispublishedtrue
cristin.fulltextoriginal
cristin.qualitycode1
dc.identifier.cristin1598286
dc.identifier.bibliographiccitationinfo:ofi/fmt:kev:mtx:ctx&ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=OncoTarget&rft.volume=9&rft.spage=19203&rft.date=2018
dc.identifier.jtitleOncoTarget
dc.identifier.volume9
dc.identifier.issue27
dc.identifier.startpage19203
dc.identifier.endpage19208
dc.identifier.doihttp://dx.doi.org/10.18632/oncotarget.24969
dc.identifier.urnURN:NBN:no-65588
dc.type.documentTidsskriftartikkelen_US
dc.type.peerreviewedPeer reviewed
dc.source.issn1949-2553
dc.identifier.fulltextFulltext https://www.duo.uio.no/bitstream/handle/10852/63025/1/Brunetti%2Bet%2Bal_Cristin-post%2B1598286.pdf
dc.type.versionPublishedVersion


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