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dc.date.accessioned2018-02-08T08:00:35Z
dc.date.available2018-02-08T08:00:35Z
dc.date.created2018-01-08T11:45:10Z
dc.date.issued2018
dc.identifier.citationRaclariu, Ancuta Cristina Heinrich, Michael Ichim, Mihael Cristi de Boer, Hugo . Benefits and limitations of DNA barcoding and metabarcoding in herbal product authentication. Phytochemical Analysis. 2017
dc.identifier.urihttp://hdl.handle.net/10852/59946
dc.description.abstractIntroduction Herbal medicines play an important role globally in the health care sector and in industrialised countries they are often considered as an alternative to mono-substance medicines. Current quality and authentication assessment methods rely mainly on morphology and analytical phytochemistry-based methods detailed in pharmacopoeias. Herbal products however are often highly processed with numerous ingredients, and even if these analytical methods are accurate for quality control of specific lead or marker compounds, they are of limited suitability for the authentication of biological ingredients. Objective To review the benefits and limitations of DNA barcoding and metabarcoding in complementing current herbal product authentication. Method Recent literature relating to DNA based authentication of medicinal plants, herbal medicines and products are summarised to provide a basic understanding of how DNA barcoding and metabarcoding can be applied to this field. Results Different methods of quality control and authentication have varying resolution and usefulness along the value chain of these products. DNA barcoding can be used for authenticating products based on single herbal ingredients and DNA metabarcoding for assessment of species diversity in processed products, and both methods should be used in combination with appropriate hyphenated chemical methods for quality control. Conclusions DNA barcoding and metabarcoding have potential in the context of quality control of both well and poorly regulated supply systems. Standardisation of protocols for DNA barcoding and DNA sequence-based identification are necessary before DNA-based biological methods can be implemented as routine analytical approaches and approved by the competent authorities for use in regulated procedures. © 2017 The Authors. Phytochemical Analysis Published by John Wiley & Sons Ltd.en_US
dc.languageEN
dc.language.isoenen_US
dc.rightsAttribution 4.0 International
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.titleBenefits and limitations of DNA barcoding and metabarcoding in herbal product authenticationen_US
dc.typeJournal articleen_US
dc.creator.authorRaclariu, Ancuta Cristina
dc.creator.authorHeinrich, Michael
dc.creator.authorIchim, Mihael Cristi
dc.creator.authorde Boer, Hugo
cristin.unitcode185,28,8,5
cristin.unitnameForskningsgruppen Planteevolusjon og DNA Metabarcoding
cristin.ispublishedtrue
cristin.fulltextoriginal
cristin.qualitycode1
dc.identifier.cristin1537562
dc.identifier.bibliographiccitationinfo:ofi/fmt:kev:mtx:ctx&ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Phytochemical Analysis&rft.volume=&rft.spage=&rft.date=2017
dc.identifier.jtitlePhytochemical Analysis
dc.identifier.volume29
dc.identifier.issue2
dc.identifier.startpage123
dc.identifier.endpage128
dc.identifier.doihttp://dx.doi.org/10.1002/pca.2732
dc.identifier.urnURN:NBN:no-62649
dc.type.documentTidsskriftartikkelen_US
dc.type.peerreviewedPeer reviewed
dc.source.issn0958-0344
dc.identifier.fulltextFulltext https://www.duo.uio.no/bitstream/handle/10852/59946/4/Raclariu_et_al-2018-Phytochemical_Analysis.pdf
dc.type.versionPublishedVersion


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