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dc.date.accessioned2017-12-11T12:37:40Z
dc.date.available2017-12-11T12:37:40Z
dc.date.created2017-11-21T14:54:02Z
dc.date.issued2017
dc.identifier.citationAbel, Marianne Hope Ystrøm, Eivind Caspersen, Ida Henriette Meltzer, Helle Margrete Aase, Heidi Torheim, Liv Elin Askeland, Ragna Bugge Reichborn-Kjennerud, Ted Brantsæter, Anne Lise . Maternal iodine intake and offspring attention-deficit/hyperactivity disorder: Results from a large prospective cohort study. Nutrients. 2017, 9(11)
dc.identifier.urihttp://hdl.handle.net/10852/59306
dc.description.abstractCurrent knowledge about the relationship between mild to moderately inadequate maternal iodine intake and/or supplemental iodine on child neurodevelopment is sparse. Using information from 77,164 mother-child pairs in the Norwegian Mother and Child Cohort Study, this study explored associations between maternal iodine intake and child attention-deficit/hyperactivity disorder (ADHD) diagnosis, registered in the Norwegian Patient Registry and maternally-reported child ADHD symptoms at eight years of age. Pregnant women reported food and supplement intakes by questionnaire in gestational week 22. In total, 1725 children (2.2%) were diagnosed with ADHD. In non-users of supplemental iodine (53,360 mothers), we found no association between iodine intake from food and risk of child ADHD diagnosis (p = 0.89), while low iodine from food (<200 µg/day) was associated with higher child ADHD symptom scores (adjusted difference in score up to 0.08 standard deviation (SD), p < 0.001, n = 19,086). In the total sample, we found no evidence of beneficial effects of maternal use of iodine-containing supplements (n = 23,804) on child ADHD diagnosis or symptom score. Initiation of iodine supplement use in gestational weeks 0–12 was associated with an increased risk of child ADHD (both measures). In conclusion, insufficient maternal iodine intake was associated with increased child ADHD symptom scores at eight years of age, but not with ADHD diagnosis. No reduction of risk was associated with maternal iodine supplement use.en_US
dc.languageEN
dc.publisherMDPI AG
dc.rightsAttribution 4.0 International
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.titleMaternal iodine intake and offspring attention-deficit/hyperactivity disorder: Results from a large prospective cohort studyen_US
dc.typeJournal articleen_US
dc.creator.authorAbel, Marianne Hope
dc.creator.authorYstrøm, Eivind
dc.creator.authorCaspersen, Ida Henriette
dc.creator.authorMeltzer, Helle Margrete
dc.creator.authorAase, Heidi
dc.creator.authorTorheim, Liv Elin
dc.creator.authorAskeland, Ragna Bugge
dc.creator.authorReichborn-Kjennerud, Ted
dc.creator.authorBrantsæter, Anne Lise
cristin.unitcode185,15,23,10
cristin.unitnameFarmasi
cristin.ispublishedtrue
cristin.fulltextoriginal
cristin.fulltextoriginal
cristin.qualitycode1
dc.identifier.cristin1516756
dc.identifier.bibliographiccitationinfo:ofi/fmt:kev:mtx:ctx&ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Nutrients&rft.volume=9&rft.spage=&rft.date=2017
dc.identifier.jtitleNutrients
dc.identifier.volume9
dc.identifier.issue11
dc.identifier.pagecount19
dc.identifier.doihttp://dx.doi.org/10.3390/nu9111239
dc.identifier.urnURN:NBN:no-62007
dc.type.documentTidsskriftartikkelen_US
dc.type.peerreviewedPeer reviewed
dc.source.issn2072-6643
dc.identifier.fulltextFulltext https://www.duo.uio.no/bitstream/handle/10852/59306/1/Abel-2017-Maternal%2BIodine%2BIntake%2Band%2BOffspring.pdf
dc.type.versionPublishedVersion
dc.relation.projectNFR/241430


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