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dc.date.accessioned2017-11-15T13:28:52Z
dc.date.available2017-11-15T13:28:52Z
dc.date.issued2015
dc.identifier.urihttp://hdl.handle.net/10852/59116
dc.description.abstractBackground. The diagnostic usefulness of electrophysiological methods in assessing disorders of consciousness (DoC) remains to be established on an individual patient level, and there is need to determine what constitutes robust experimental paradigm to elicit electrophysiological indices of covert cognitive capacity. Objectives. Two tasks encompassing active and passive conditions were explored in an event-related potentials (ERP) study. The task robustness was studied in healthy controls, and their utility to detect covert signs of command-following on an individual patient level was investigated in patients in a minimally conscious state (MCS). Methods. Twenty healthy controls and 20 MCS patients participated. The active tasks included (1) listening for a change of pitch in the subject’s own name (SON) and (2) counting SON, both contrasted to passive conditions. Midline ERPs are reported. Results. A larger P3 response was detected in the counting task compared to active listening to pitch change in the healthy controls. On an individual level, the counting task revealed a higher rate of responders among both healthy subjects and MCS patients. Conclusion. ERP paradigms involving actively counting SON represent a robust paradigm in probing for volitional cognition in minimally conscious patients and add important diagnostic information in some patients.en_US
dc.language.isoenen_US
dc.relation.ispartofHauger, Solveig Lægreid (2017) Clinical utility of cognitive Event Related Potentials (ERP) in severe acquired brain injury - diagnostic value of ERP in prolonged disorders of consciousness and prognostic utility in the sub-acute phase after very severe traumatic brain injury. Doctoral thesis. http://hdl.handle.net/10852/59118
dc.relation.urihttp://hdl.handle.net/10852/59118
dc.rightsAttribution 3.0 Unported
dc.rights.urihttps://creativecommons.org/licenses/by/3.0/
dc.titleNeurophysiological Indicators of Residual Cognitive Capacity in the Minimally Conscious Stateen_US
dc.typeJournal articleen_US
dc.creator.authorHauger, Solveig L.
dc.creator.authorSchnakers, Caroline
dc.creator.authorAndersson, Stein
dc.creator.authorBecker, Frank
dc.creator.authorMoberget, Torgeir
dc.creator.authorGiacino, Joseph T.
dc.creator.authorSchanke, Anne-Kristine
dc.creator.authorLøvstad, Marianne
dc.identifier.jtitleBehavioural Neurology
dc.identifier.volume2015
dc.identifier.doihttps://doi.org/10.1155/2015/145913
dc.identifier.urnURN:NBN:no-61519
dc.type.documentTidsskriftartikkelen_US
dc.type.peerreviewedPeer reviewed
dc.identifier.fulltextFulltext https://www.duo.uio.no/bitstream/handle/10852/59116/1/145913.pdf
dc.type.versionPublishedVersion
cristin.articleid145913


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