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dc.date.accessioned2017-10-30T08:41:47Z
dc.date.available2017-10-30T08:41:47Z
dc.date.created2017-01-31T21:28:45Z
dc.date.issued2016
dc.identifier.citationSaberniak, Jørg Leren, Ida Skrinde Håland, Trine Synnøve Fink Beitnes, Jan Otto Hopp, Einar Borgquist, Rasmus Edvardsen, Thor Haugaa, Kristina . Comparison of patients with early phase arrhythmogenic right ventricular cardiomyopathy and right ventricular outflow tract ventricular tachycardia. European Heart Journal-Cardiovascular Imaging. 2016, 18(1), 62-69
dc.identifier.urihttp://hdl.handle.net/10852/58982
dc.description.abstractAims: Differentiation between early-phase arrhythmogenic right ventricular cardiomyopathy (ARVC) and right ventricular outflow tract (RVOT)-ventricular tachycardia (VT) can be challenging, and correct diagnosis is important. We compared electrocardiogram (ECG) parameters and morphological right ventricular (RV) abnormalities and investigated if ECG and cardiac imaging can help to discriminate early-phase ARVC from RVOT-VT patients. Methods and results: We included 44 consecutive RVOT-VT (47+14 years) and 121 ARVC patients (42+17 years). Of the ARVC patients, 77 had definite ARVC and 44 had early-phase ARVC disease. All underwent clinical examination, ECG, and Holter monitoring. Frequency of premature ventricular complexes (PVC) was expressed as percent per total beats/24 h (%PVC), and PVC configuration was recorded. By echocardiography, we assessed indexed RV basal diameter (RVD), indexed RVOT diameter, and RV and left ventricular (LV) function. RV mechanical dispersion (RVMD), reflecting RV contraction heterogeneity, was assessed by speckle-tracking strain echocardiography. RV ejection fraction (RVEF) was assessed by cardiac magnetic resonance imaging (CMR). Patients with early-phase ARVC had lower %PVC by Holter and PVC more frequently originated from the RV lateral free wall (both P , 0.001). RVD was larger (21+3 vs. 19+2 mm, P , 0.01), RVMD was more pronounced (22+15 vs. 15+13 ms, P ¼ 0.03), and RVEF by CMR was decreased (41+8 vs. 49+4%, P , 0.001) in early-phase ARVC vs. RVOT-VT patients. Conclusion: Patients with early-phase ARVC had structural abnormalities with lower RVEF, increased RVD, and pronounced RVMD in addition to lower %PVC by Holter compared with RVOT-VT patients. These parameters can help correct diagnosis in patients with unclear phenotypes.
dc.languageEN
dc.publisherOxford University Press
dc.relation.ispartofJørg Saberniak (2017) Arrhythmogenic right ventricular cardiomyopathy (ARVC)- Impact of exercise on cardiac outcome, differential diagnoses and risk stratification of arrhythmic events. Doctoral thesis http://hdl.handle.net/10852/58961
dc.relation.urihttp://hdl.handle.net/10852/58961
dc.rightsAttribution 4.0 International
dc.rights.urihttp://creativecommons.org/licenses/by-nc/4.0/
dc.titleComparison of patients with early phase arrhythmogenic right ventricular cardiomyopathy and right ventricular outflow tract ventricular tachycardia
dc.typeJournal article
dc.creator.authorSaberniak, Jørg
dc.creator.authorLeren, Ida Skrinde
dc.creator.authorHåland, Trine Synnøve Fink
dc.creator.authorBeitnes, Jan Otto
dc.creator.authorHopp, Einar
dc.creator.authorBorgquist, Rasmus
dc.creator.authorEdvardsen, Thor
dc.creator.authorHaugaa, Kristina
cristin.unitcode185,53,15,13
cristin.unitnameKardiologisk avdeling
cristin.ispublishedtrue
cristin.fulltextoriginal
cristin.qualitycode1
dc.identifier.cristin1444621
dc.identifier.bibliographiccitationinfo:ofi/fmt:kev:mtx:ctx&ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=European Heart Journal-Cardiovascular Imaging&rft.volume=18&rft.spage=62&rft.date=2016
dc.identifier.jtitleEuropean Heart Journal-Cardiovascular Imaging
dc.identifier.volume18
dc.identifier.issue1
dc.identifier.startpage62
dc.identifier.endpage69
dc.identifier.doihttp://dx.doi.org/10.1093/ehjci/jew014
dc.identifier.urnURN:NBN:no-61811
dc.type.documentTidsskriftartikkel
dc.type.peerreviewedPeer reviewed
dc.source.issn2047-2404
dc.identifier.fulltextFulltext https://www.duo.uio.no/bitstream/handle/10852/58982/2/jew014.pdf
dc.type.versionPublishedVersion


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