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dc.date.accessioned2017-10-13T10:53:04Z
dc.date.available2017-10-13T10:53:04Z
dc.date.issued2017
dc.identifier.urihttp://hdl.handle.net/10852/58763
dc.language.isoenen_US
dc.relation.haspartPaper I: Total synthesis and antileukemic evaluations of the phenazine 5,10-dioxide natural products iodinin, myxin and their derivatives. Viktorsson, E. Ö.; Grøthe, B. M.; Aesoy, R.; Sabir, M.; Snellingen, S.; Prandina, A.; Åstrand, O. A. H.; Bonge-Hansen, T.; Døskeland, S. O.; Herfindal, L. and Rongved, P. Bioorg. Med. Chem. 2017, 25 (7): 2285-2293. The article is not available in DUO due to publisher restrictions. The published version is available at: https://doi.org/10.1016/j.bmc.2017.02.058
dc.relation.haspartPaper II: New prodrugs and analogues of the phenazine 5,10-dioxide natural products iodinin and myxin promote selective cytotoxicity towards human acute myeloid leukemia cells. Viktorsson, E. Ö.; Aesoy, R.; Støa, S.; Døskeland, S. O.; Herfindal, L. and Rongved, P. Prepared manuscript. The paper is not available in DUO awaiting publishing.
dc.relation.haspartPaper III: Synthesis, in vitro and in vivo biological evaluation of new oxysterols as modulators of the liver X receptors. Åstrand, O. A. H.; Viktorsson, E. Ö.; Kristensen, A. L.; Ekeberg, D.; Røberg-Larsen, H.; Wilson, S. R.; Gabrielsen, M.; Sylte, I.; Rustan, A.; Thoresen, H.; Rongved, P.; Kase, E. T. J. Steroid. Biochem.. 2017, 165, 323-330. The article is not available in DUO due to publisher restrictions. The published version is available at: https://doi.org/10.1016/j.jsbmb.2016.07.010
dc.relation.haspartPaper IV: Regulation of liver X receptor target genes by 22-functionalized oxysterols. Synthesis, in silico and in vitro evaluations. Viktorsson, E. Ö.; Gabrielsen, M.; Kumarachandran, N.; Sylte, I.; Rongved, P.; Åstrand, O. A. H.; Kase, E. Steroids 2017, 118, 119-127. The article is not available in DUO due to publisher restrictions. The published version is available at: https://doi.org/10.1016/j.steroids.2016.12.003
dc.relation.haspartPaper V: Crystal structure of (S)-2-[(3S,8S,9S,10R,13S,14S,17R)-3-hydroxy-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]-Nmethoxy-N-methylpropanamide (Fernholz Weinreb amide). Viktorsson, E. Ö.; Åstrand, O. A. H.; Haseeb, R. S.; Görbitz, C. H. and Rongved, P. Acta. Crystallogr. E. 2015, 71 (3): 275-277. The article is included in the thesis. Also available at: https://doi.org/10.1107/S2056989015001747
dc.relation.urihttps://doi.org/10.1016/j.bmc.2017.02.058
dc.relation.urihttps://doi.org/10.1016/j.jsbmb.2016.07.010
dc.relation.urihttps://doi.org/10.1016/j.steroids.2016.12.003
dc.relation.urihttps://doi.org/10.1107/S2056989015001747
dc.titleDrug Discovery, Design and Synthesis of Polycyclic Regulators of Cancer Cells and Nuclear Receptors: Phenazine 5,10-dioxides and Oxysterolsen_US
dc.typeDoctoral thesisen_US
dc.creator.authorViktorsson, Elvar Örn
dc.identifier.urnURN:NBN:no-61413
dc.type.documentDoktoravhandlingen_US
dc.identifier.fulltextFulltext https://www.duo.uio.no/bitstream/handle/10852/58763/1/PhD--Viktorsson-2017.pdf


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