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dc.date.accessioned2017-09-24T12:12:49Z
dc.date.available2017-09-24T12:12:49Z
dc.date.created2017-09-18T09:49:11Z
dc.date.issued2017
dc.identifier.citationBjelland, Elisabeth Krefting Owe, Katrine Mari Nordeng, Hedvig Marie Egeland Engdahl, Bo Lars Kristiansson, Per Vangen, Siri Eberhard-Gran, Malin . Does progestin-only contraceptive use after pregnancy affect recovery from pelvic girdle pain? A prospective population study. PLoS ONE. 2017, 12(9)
dc.identifier.urihttp://hdl.handle.net/10852/58511
dc.description.abstractObjective: To estimate associations of progestin-only contraceptives with persistent pelvic girdle pain 18 months after delivery. Methods Prospective population based cohort study during the years 2003–2011. We included 20,493 women enrolled in the Norwegian Mother and Child Cohort Study who reported pelvic girdle pain in pregnancy week 30. Data were obtained by 3 self-administered questionnaires and the exposure was obtained by linkage to the Prescription Database of Norway. The outcome was pelvic girdle pain 18 months after delivery. Results: Pelvic girdle pain 18 months after delivery was reported by 9.7% (957/9830) of women with dispense of a progestin-only contraceptive and by 10.5% (1114/10,663) of women without dispense (adjusted odds ratio 0.93; 95% CI 0.84–1.02). In sub-analyses, long duration of exposure to a progestin intrauterine device or progestin-only oral contraceptives was associated with reduced odds of persistent pelvic girdle pain (Ptrend = 0.021 and Ptrend = 0.005). Conversely, long duration of exposure to progestin injections and/or a progestin implant was associated with modest increased odds of persistent pelvic girdle pain (Ptrend = 0.046). Early timing of progestin-only contraceptive dispense following delivery (≤3 months) was not significantly associated with persistent pelvic girdle pain. Conclusions: Our findings suggest a small beneficial effect of progestin intrauterine devices and progestin-only oral contraceptives on recovery from pelvic girdle pain. We cannot completely rule out an opposing adverse effect of exposure to progestin injections and/or progestin implants. However, the modest increased odds of persistent pelvic girdle pain among these users could be a result of unmeasured confounding.en_US
dc.languageEN
dc.publisherPublic Library of Science (PLoS)
dc.rightsAttribution 4.0 International
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.titleDoes progestin-only contraceptive use after pregnancy affect recovery from pelvic girdle pain? A prospective population studyen_US
dc.typeJournal articleen_US
dc.creator.authorBjelland, Elisabeth Krefting
dc.creator.authorOwe, Katrine Mari
dc.creator.authorNordeng, Hedvig Marie Egeland
dc.creator.authorEngdahl, Bo Lars
dc.creator.authorKristiansson, Per
dc.creator.authorVangen, Siri
dc.creator.authorEberhard-Gran, Malin
cristin.unitcode185,15,23,10
cristin.unitnameFarmasi
cristin.ispublishedtrue
cristin.fulltextoriginal
cristin.qualitycode1
dc.identifier.cristin1494628
dc.identifier.bibliographiccitationinfo:ofi/fmt:kev:mtx:ctx&ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=PLoS ONE&rft.volume=12&rft.spage=&rft.date=2017
dc.identifier.jtitlePLoS ONE
dc.identifier.volume12
dc.identifier.issue9
dc.identifier.pagecount14
dc.identifier.doihttp://dx.doi.org/10.1371/journal. pone.0184071
dc.identifier.urnURN:NBN:no-61234
dc.type.documentTidsskriftartikkelen_US
dc.type.peerreviewedPeer reviewed
dc.source.issn1932-6203
dc.identifier.fulltextFulltext https://www.duo.uio.no/bitstream/handle/10852/58511/1/Bjelland_2017_Doe.pdf
dc.type.versionPublishedVersion
cristin.articleide0184071


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