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dc.date.accessioned2017-04-26T14:03:28Z
dc.date.available2017-04-26T14:03:28Z
dc.date.created2012-12-18T13:43:09Z
dc.date.issued2001
dc.identifier.citationNygaard, Egil Reichelt, Karl Ludvig Fagan, Joseph F. . The relation between the psychological functioning of children with Down syndrome and their urine peptide levels and levels of serum antibodies to food proteins. Down's syndrome: research and practice. 2001, 6(3), 139-145
dc.identifier.urihttp://hdl.handle.net/10852/55277
dc.description.abstractAims: To investigate the relation between psychological functioning of subjects with Down syndrome, and their levels of urine peptide and serum antibodies to food proteins. Methods: 55 children with Down syndrome in a cross-sectional study. Psychological functioning was measured by the Stanford-Binet Intelligence Scale: Fourth Edition, McCarthy Scales of Children's Abilities and Fagan's computer based test of novelty preference. Results: The participants, and their siblings, were found to have significantly increased total urine peptide levels. There were no significant correlations between peptide levels and psychological functioning. Significantly increased levels of IgG activity to gliadin and gluten, and IgA activity to gliadin, gluten and casein were found. There were significant negative correlations (Spearman r=-0.13 to -0.51) between psychological functioning, and IgG and IgA activity to gliadin and gluten. Conclusions: A significant relation between antibodies to gluten and psychological functioning was documented. The mechanism and potential causal link are still unknown.en_US
dc.languageEN
dc.publisherUniversity of Portsmouth, Sarah Duffen Centre
dc.rightsAttribution-NonCommercial 3.0 Unported
dc.rights.urihttps://creativecommons.org/licenses/by-nc/3.0/
dc.titleThe relation between the psychological functioning of children with Down syndrome and their urine peptide levels and levels of serum antibodies to food proteinsen_US
dc.typeJournal articleen_US
dc.creator.authorNygaard, Egil
dc.creator.authorReichelt, Karl Ludvig
dc.creator.authorFagan, Joseph F.
cristin.unitcode185,53,13,12
cristin.unitnamePediatrisk forskningsinstitutt
cristin.ispublishedtrue
cristin.fulltextoriginal
cristin.fulltextoriginal
dc.identifier.cristin975093
dc.identifier.bibliographiccitationinfo:ofi/fmt:kev:mtx:ctx&ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Down's syndrome: research and practice&rft.volume=6&rft.spage=139&rft.date=2001
dc.identifier.jtitleDown's syndrome: research and practice
dc.identifier.volume6
dc.identifier.issue3
dc.identifier.startpage139
dc.identifier.endpage145
dc.identifier.doihttp://dx.doi.org/10.3104/reports.107
dc.identifier.urnURN:NBN:no-58076
dc.type.documentTidsskriftartikkelen_US
dc.type.peerreviewedPeer reviewed
dc.source.issn0968-7912
dc.identifier.fulltextFulltext https://www.duo.uio.no/bitstream/handle/10852/55277/2/Nygaard%2Bet%2Bal%2B2001.pdf
dc.type.versionPublishedVersion


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