With the increased appropriation of health information systems in develop- ing countries, scholars have identified that the systems implemented often fail to scale and countries are left with prototypes that are hard to scale when researchers and donor organizations disappear. This thesis is aimed at exploring how stakeholders can cater for a successful implementation of a health information system in developing countries. The research was conducted in Zimbabwe and involved rolling out an Android based tracker application for tracking Malaria and Malaria breeding sites. This thesis contributes to theory by adopting Heeks (2006)’s design-reality gap model, when analyzing the findings from the study. The research was conducted using the action case method, the research found that successful implementations of health information systems in developing countries are dependant on the implementation’s ability to scale and sustain in the local con- text and that more focus needs to be directed towards capacity building and documentation.