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dc.date.accessioned2017-01-11T08:08:04Z
dc.date.available2017-01-11T08:08:04Z
dc.date.issued2017
dc.identifier.urihttp://hdl.handle.net/10852/53502
dc.description.abstractThe work presented contributes to the further understanding and establishment of decision-making deficits in adults with ADHD. The meta-analysis in article I clearly identifies deficits in decision-making as an important factor in ADHD. The mechanistic, model-based fMRI analysis in article II provides strong evidence for reduced striatal reward coding in ADHD, and that treatment with methylphenidate at least partly remediates this abnormality. Lower-level cognitive functions are thus disrupted in ADHD, not only higher-order cognitive processes such as attention or executive functions. The data-driven network analysis in article III provided novel evidence for the importance of sustained default mode suppression for successful decision-making, and that adults with ADHD had difficulties in sustaining such suppression.
dc.language.isoenen_US
dc.relation.haspartArticle I: Mowinckel, A. M., Pedersen, M., Eilertsen, E. & Biele, G., (2015). A Meta-Analysis of Decision-Making and Attention in Adults With ADHD. Journal of Attention Disorders, 19(5), 355-367. The paper is not available in DUO due to publisher restrictions. The published version is available at: http://dx.doi.org/10.1177/10870554714558872
dc.relation.haspartArticle II: Mowinckel, A. M., Pedersen, M., Ziegler, S., Fredriksen, M., Bjørnerud, A., Endestad, T. & Biele, G., Aberrant reward processing is alleviated by methylphenidate in adults with ADHD: A randomized, placebo-controlled trial. (Submitted) The paper is not available in DUO awaiting publishing.
dc.relation.haspartArticle III: Mowinckel, A. M., Alnæs, D., Pedersen, M. L., Ziegler, S., Fredriksen, M., Kaufman, T., Sonuga-Barke, E., Westlye, L. T. & Biele, G. Diminished sustained default-mode suppression during decision-making in ADHD: remediation by methylphenidate? (Submitted) The paper is not available in DUO awaiting publishing.
dc.relation.urihttp://dx.doi.org/10.1177/10870554714558872
dc.titleNeurocognitive processes of decision-making in adults with ADHD – Deficits in behavior and functional brain processing, and the effects of methylphenidateen_US
dc.typeDoctoral thesisen_US
dc.creator.authorMowinckel, Athanasia Monika
dc.identifier.urnURN:NBN:no-56699
dc.type.documentDoktoravhandlingen_US
dc.identifier.fulltextFulltext https://www.duo.uio.no/bitstream/handle/10852/53502/1/Mowinckel-Neurocognitive-Processes.pdf


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