Neurocognitive processes of decision-making in adults with ADHD – Deficits in behavior and functional brain processing, and the effects of methylphenidate
Appears in the following Collection
- Psykologisk institutt 
AbstractThe work presented contributes to the further understanding and establishment of decision-making deficits in adults with ADHD. The meta-analysis in article I clearly identifies deficits in decision-making as an important factor in ADHD. The mechanistic, model-based fMRI analysis in article II provides strong evidence for reduced striatal reward coding in ADHD, and that treatment with methylphenidate at least partly remediates this abnormality. Lower-level cognitive functions are thus disrupted in ADHD, not only higher-order cognitive processes such as attention or executive functions. The data-driven network analysis in article III provided novel evidence for the importance of sustained default mode suppression for successful decision-making, and that adults with ADHD had difficulties in sustaining such suppression.
List of papers
|Article I: Mowinckel, A. M., Pedersen, M., Eilertsen, E. & Biele, G., (2015). A Meta-Analysis of Decision-Making and Attention in Adults With ADHD. Journal of Attention Disorders, 19(5), 355-367. The paper is not available in DUO due to publisher restrictions. The published version is available at: https://doi.org/10.1177/10870554714558872|
|Article II: Mowinckel, A. M., Pedersen, M., Ziegler, S., Fredriksen, M., Bjørnerud, A., Endestad, T. & Biele, G., Aberrant reward processing is alleviated by methylphenidate in adults with ADHD: A randomized, placebo-controlled trial. (Submitted) The paper is not available in DUO awaiting publishing.|
|Article III: Mowinckel, A. M., Alnæs, D., Pedersen, M. L., Ziegler, S., Fredriksen, M., Kaufman, T., Sonuga-Barke, E., Westlye, L. T. & Biele, G. Diminished sustained default-mode suppression during decision-making in ADHD: remediation by methylphenidate? (Submitted) The paper is not available in DUO awaiting publishing.|