Background. Patients living with prolonged severe physical injuries and their close family members are commonly confronted with major requirements of long-term adjustments to a myriad of post-injury changes. A substantial amount of clinical research is dedicated to assess and document increased risks of shortcomings and pathology due to the altered life conditions. However, approaches investigating resilience and positive adjustment are increasingly recognized as useful within the physical rehabilitation psychology field. Objective. The purpose of the present study is to explore long-term processes of resilience in face of a spinal cord injury within a family context. Methods. Six qualitative in-depth interviews and two focus groups were conducted with a total of 14 participants. The narratives collected were thematically analysed. Results. Narratives illustrating family adjustment and resilience were categorized into three broad themes: (1) Individual strengths, (2) Relational flexibility, and (3) Contextual influence. Findings support previous notions about the complexity of the resilience phenomenon, and additionally add new aspects to the operational definitions by emphasizing relational flexibility and the qualitative investigation of resilience as potentially useful for the future. Empirical considerations, operational definitions, and implications are discussed.