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Now showing items 31-40 of 44
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
The brain is the most complex of human organs, and the pathophysiology underlying abnormal brain function in psychiatric disorders is largely unknown. Despite the rapid development of diagnostic tools and treatments in ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
Reduced telomere length (TL) and structural brain abnormalities have been reported in patients with schizophrenia (SZ) and bipolar disorder (BD). Childhood traumatic events are more frequent in SZ and BD than in healthy ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
The thickness of the cerebral cortical sheet and its surface area are highly heritable traits thought to have largely distinct polygenic architectures. Despite large-scale efforts, the majority of their genetic determinants ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
The brain functional connectome forms a relatively stable and idiosyncratic backbone that can be used for identification or “fingerprinting” of individuals with a high level of accuracy. While previous cross‐sectional ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Epilepsy is clinically heterogeneous, and neurological or psychiatric comorbidities are frequently observed in patients. It has not been tested whether common risk variants for generalized or focal epilepsy are enriched ...
(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2020)
The cerebral cortex underlies our complex cognitive capabilities, yet little is known about the specific genetic loci that influence human cortical structure. To identify genetic variants that affect cortical structure, ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
A cerebral stroke is characterized by compromised brain function due to an interruption in cerebrovascular blood supply. Although stroke incurs focal damage determined by the vascular territory affected, clinical symptoms ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Abstract Cortical thickness, surface area and volumes vary with age and cognitive function, and in neurological and psychiatric diseases. Here we report heritability, genetic correlations and genome-wide associations of ...
(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2020)
Sensitivity to external demands is essential for adaptation to dynamic environments, but comes at the cost of increased risk of adverse outcomes when facing poor environmental conditions. Here, we apply a novel methodology ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
Human adolescence is a period of rapid changes in cognition and goal-directed behavior, and it constitutes a major transitional phase towards adulthood. One of the mechanisms suggested to underlie the protracted maturation ...