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dc.contributor.authorPapadopoulos, Nikolaos G
dc.contributor.authorAgache, Ioana
dc.contributor.authorBavbek, Sevim
dc.contributor.authorBilo, Beatrice M
dc.contributor.authorBraido, Fulvio
dc.contributor.authorCardona, Victoria
dc.contributor.authorCustovic, Adnan
dc.contributor.authordeMonchy, Jan
dc.contributor.authorDemoly, Pascal
dc.contributor.authorEigenmann, Philippe
dc.contributor.authorGayraud, Jacques
dc.contributor.authorGrattan, Clive
dc.contributor.authorHeffler, Enrico
dc.contributor.authorHellings, Peter W
dc.contributor.authorJutel, Marek
dc.contributor.authorKnol, Edward
dc.contributor.authorLötvall, Jan
dc.contributor.authorMuraro, Antonella
dc.contributor.authorPoulsen, Lars K
dc.contributor.authorRoberts, Graham
dc.contributor.authorSchmid-Grendelmeier, Peter
dc.contributor.authorSkevaki, Chrysanthi
dc.contributor.authorTriggiani, Massimo
dc.contributor.authorvanRee, Ronald
dc.contributor.authorWerfel, Thomas
dc.contributor.authorFlood, Breda
dc.contributor.authorPalkonen, Susanna
dc.contributor.authorSavli, Roberta
dc.contributor.authorAllegri, Pia
dc.contributor.authorAnnesi-Maesano, Isabella
dc.contributor.authorAnnunziato, Francesco
dc.contributor.authorAntolin-Amerigo, Dario
dc.contributor.authorApfelbacher, Christian
dc.contributor.authorBlanca, Miguel
dc.contributor.authorBogacka, Ewa
dc.contributor.authorBonadonna, Patrizia
dc.contributor.authorBonini, Matteo
dc.contributor.authorBoyman, Onur
dc.contributor.authorBrockow, Knut
dc.contributor.authorBurney, Peter
dc.contributor.authorButers, Jeroen
dc.contributor.authorButiene, Indre
dc.contributor.authorCalderon, Moises
dc.contributor.authorCardell, Lars O
dc.contributor.authorCaubet, Jean-Christoph
dc.contributor.authorCelenk, Sevcan
dc.contributor.authorCichocka-Jarosz, Ewa
dc.contributor.authorCingi, Cemal
dc.contributor.authorCouto, Mariana
dc.contributor.authordeJong, Nicolette
dc.contributor.authorDel Giacco, Stefano
dc.contributor.authorDouladiris, Nikolaos
dc.contributor.authorFassio, Filippo
dc.contributor.authorFauquert, Jean-Luc
dc.contributor.authorFernandez, Javier
dc.contributor.authorRivas, Montserrat F
dc.contributor.authorFerrer, Marta
dc.contributor.authorFlohr, Carsten
dc.contributor.authorGardner, James
dc.contributor.authorGenuneit, Jon
dc.contributor.authorGevaert, Philippe
dc.contributor.authorGroblewska, Anna
dc.contributor.authorHamelmann, Eckard
dc.contributor.authorHoffmann, Hans J
dc.contributor.authorHoffmann-Sommergruber, Karin
dc.contributor.authorHovhannisyan, Lilit
dc.contributor.authorHox, Valérie
dc.contributor.authorJahnsen, Frode L
dc.contributor.authorKalayci, Ömer
dc.contributor.authorKalpaklioglu, Ayse F
dc.contributor.authorKleine-Tebbe, Jörg
dc.contributor.authorKonstantinou, George
dc.contributor.authorKurowski, Marcin
dc.contributor.authorLau, Susanne
dc.contributor.authorLauener, Roger
dc.contributor.authorLauerma, Antti
dc.contributor.authorLogan, Kirsty
dc.contributor.authorMagnan, Antoine
dc.contributor.authorMakowska, Joanna
dc.contributor.authorMakrinioti, Heidi
dc.contributor.authorMangina, Paraskevi
dc.contributor.authorManole, Felicia
dc.contributor.authorMari, Adriano
dc.contributor.authorMazon, Angel
dc.contributor.authorMills, Clare
dc.contributor.authorMingomataj, ErvinÇ
dc.contributor.authorNiggemann, Bodo
dc.contributor.authorNilsson, Gunnar
dc.contributor.authorOllert, Markus
dc.contributor.authorO’Mahony, Liam
dc.contributor.authorO’Neil, Serena
dc.contributor.authorPala, Gianni
dc.contributor.authorPapi, Alberto
dc.contributor.authorPassalacqua, Gianni
dc.contributor.authorPerkin, Michael
dc.contributor.authorPfaar, Oliver
dc.contributor.authorPitsios, Constantinos
dc.contributor.authorQuirce, Santiago
dc.contributor.authorRaap, Ulrike
dc.contributor.authorRaulf-Heimsoth, Monika
dc.contributor.authorRhyner, Claudio
dc.contributor.authorRobson-Ansley, Paula
dc.contributor.authorAlves, Rodrigo R
dc.contributor.authorRoje, Zeljka
dc.contributor.authorRondon, Carmen
dc.contributor.authorRudzeviciene, Odilija
dc.contributor.authorRuëff, Franziska
dc.contributor.authorRukhadze, Maia
dc.contributor.authorRumi, Gabriele
dc.contributor.authorSackesen, Cansin
dc.contributor.authorSantos, Alexandra F
dc.contributor.authorSantucci, Annalisa
dc.contributor.authorScharf, Christian
dc.contributor.authorSchmidt-Weber, Carsten
dc.contributor.authorSchnyder, Benno
dc.contributor.authorSchwarze, Jürgen
dc.contributor.authorSenna, Gianenrico
dc.contributor.authorSergejeva, Svetlana
dc.contributor.authorSeys, Sven
dc.contributor.authorSiracusa, Andrea
dc.contributor.authorSkypala, Isabel
dc.contributor.authorSokolowska, Milena
dc.contributor.authorSpertini, Francois
dc.contributor.authorSpiewak, Radoslaw
dc.contributor.authorSprikkelman, Aline
dc.contributor.authorSturm, Gunter
dc.contributor.authorSwoboda, Ines
dc.contributor.authorTerreehorst, Ingrid
dc.contributor.authorToskala, Elina
dc.contributor.authorTraidl-Hoffmann, Claudia
dc.contributor.authorVenter, Carina
dc.contributor.authorVlieg-Boerstra, Berber
dc.contributor.authorWhitacker, Paul
dc.contributor.authorWorm, Margitta
dc.contributor.authorXepapadaki, Paraskevi
dc.contributor.authorAkdis, Cezmi A
dc.date.accessioned2015-10-20T10:55:02Z
dc.date.available2015-10-20T10:55:02Z
dc.date.issued2012
dc.identifier.citationClinical and Translational Allergy. 2012 Nov 02;2(1):21
dc.identifier.urihttp://hdl.handle.net/10852/47123
dc.description.abstractIn less than half a century, allergy, originally perceived as a rare disease, has become a major public health threat, today affecting the lives of more than 60 million people in Europe, and probably close to one billion worldwide, thereby heavily impacting the budgets of public health systems. More disturbingly, its prevalence and impact are on the rise, a development that has been associated with environmental and lifestyle changes accompanying the continuous process of urbanization and globalization. Therefore, there is an urgent need to prioritize and concert research efforts in the field of allergy, in order to achieve sustainable results on prevention, diagnosis and treatment of this most prevalent chronic disease of the 21st century. The European Academy of Allergy and Clinical Immunology (EAACI) is the leading professional organization in the field of allergy, promoting excellence in clinical care, education, training and basic and translational research, all with the ultimate goal of improving the health of allergic patients. The European Federation of Allergy and Airways Diseases Patients’ Associations (EFA) is a non-profit network of allergy, asthma and Chronic Obstructive Pulmonary Disorder (COPD) patients’ organizations. In support of their missions, the present EAACI Position Paper, in collaboration with EFA, highlights the most important research needs in the field of allergy to serve as key recommendations for future research funding at the national and European levels. Although allergies may involve almost every organ of the body and an array of diverse external factors act as triggers, there are several common themes that need to be prioritized in research efforts. As in many other chronic diseases, effective prevention, curative treatment and accurate, rapid diagnosis represent major unmet needs. Detailed phenotyping/endotyping stands out as widely required in order to arrange or re-categorize clinical syndromes into more coherent, uniform and treatment-responsive groups. Research efforts to unveil the basic pathophysiologic pathways and mechanisms, thus leading to the comprehension and resolution of the pathophysiologic complexity of allergies will allow for the design of novel patient-oriented diagnostic and treatment protocols. Several allergic diseases require well-controlled epidemiological description and surveillance, using disease registries, pharmacoeconomic evaluation, as well as large biobanks. Additionally, there is a need for extensive studies to bring promising new biotechnological innovations, such as biological agents, vaccines of modified allergen molecules and engineered components for allergy diagnosis, closer to clinical practice. Finally, particular attention should be paid to the difficult-to-manage, precarious and costly severe disease forms and/or exacerbations. Nonetheless, currently arising treatments, mainly in the fields of immunotherapy and biologicals, hold great promise for targeted and causal management of allergic conditions. Active involvement of all stakeholders, including Patient Organizations and policy makers are necessary to achieve the aims emphasized herein.
dc.language.isoeng
dc.rightsPapadopoulos et al.; licensee BioMed Central Ltd.
dc.rightsAttribution 2.0 Generic
dc.rights.urihttp://creativecommons.org/licenses/by/2.0/
dc.titleResearch needs in allergy: an EAACI position paper, in collaboration with EFA
dc.typeJournal article
dc.date.updated2015-10-20T10:55:03Z
dc.creator.authorPapadopoulos, Nikolaos G
dc.creator.authorAgache, Ioana
dc.creator.authorBavbek, Sevim
dc.creator.authorBilo, Beatrice M
dc.creator.authorBraido, Fulvio
dc.creator.authorCardona, Victoria
dc.creator.authorCustovic, Adnan
dc.creator.authordeMonchy, Jan
dc.creator.authorDemoly, Pascal
dc.creator.authorEigenmann, Philippe
dc.creator.authorGayraud, Jacques
dc.creator.authorGrattan, Clive
dc.creator.authorHeffler, Enrico
dc.creator.authorHellings, Peter W
dc.creator.authorJutel, Marek
dc.creator.authorKnol, Edward
dc.creator.authorLötvall, Jan
dc.creator.authorMuraro, Antonella
dc.creator.authorPoulsen, Lars K
dc.creator.authorRoberts, Graham
dc.creator.authorSchmid-Grendelmeier, Peter
dc.creator.authorSkevaki, Chrysanthi
dc.creator.authorTriggiani, Massimo
dc.creator.authorvanRee, Ronald
dc.creator.authorWerfel, Thomas
dc.creator.authorFlood, Breda
dc.creator.authorPalkonen, Susanna
dc.creator.authorSavli, Roberta
dc.creator.authorAllegri, Pia
dc.creator.authorAnnesi-Maesano, Isabella
dc.creator.authorAnnunziato, Francesco
dc.creator.authorAntolin-Amerigo, Dario
dc.creator.authorApfelbacher, Christian
dc.creator.authorBlanca, Miguel
dc.creator.authorBogacka, Ewa
dc.creator.authorBonadonna, Patrizia
dc.creator.authorBonini, Matteo
dc.creator.authorBoyman, Onur
dc.creator.authorBrockow, Knut
dc.creator.authorBurney, Peter
dc.creator.authorButers, Jeroen
dc.creator.authorButiene, Indre
dc.creator.authorCalderon, Moises
dc.creator.authorCardell, Lars O
dc.creator.authorCaubet, Jean-Christoph
dc.creator.authorCelenk, Sevcan
dc.creator.authorCichocka-Jarosz, Ewa
dc.creator.authorCingi, Cemal
dc.creator.authorCouto, Mariana
dc.creator.authordeJong, Nicolette
dc.creator.authorDel Giacco, Stefano
dc.creator.authorDouladiris, Nikolaos
dc.creator.authorFassio, Filippo
dc.creator.authorFauquert, Jean-Luc
dc.creator.authorFernandez, Javier
dc.creator.authorRivas, Montserrat F
dc.creator.authorFerrer, Marta
dc.creator.authorFlohr, Carsten
dc.creator.authorGardner, James
dc.creator.authorGenuneit, Jon
dc.creator.authorGevaert, Philippe
dc.creator.authorGroblewska, Anna
dc.creator.authorHamelmann, Eckard
dc.creator.authorHoffmann, Hans J
dc.creator.authorHoffmann-Sommergruber, Karin
dc.creator.authorHovhannisyan, Lilit
dc.creator.authorHox, Valérie
dc.creator.authorJahnsen, Frode L
dc.creator.authorKalayci, Ömer
dc.creator.authorKalpaklioglu, Ayse F
dc.creator.authorKleine-Tebbe, Jörg
dc.creator.authorKonstantinou, George
dc.creator.authorKurowski, Marcin
dc.creator.authorLau, Susanne
dc.creator.authorLauener, Roger
dc.creator.authorLauerma, Antti
dc.creator.authorLogan, Kirsty
dc.creator.authorMagnan, Antoine
dc.creator.authorMakowska, Joanna
dc.creator.authorMakrinioti, Heidi
dc.creator.authorMangina, Paraskevi
dc.creator.authorManole, Felicia
dc.creator.authorMari, Adriano
dc.creator.authorMazon, Angel
dc.creator.authorMills, Clare
dc.creator.authorMingomataj, ErvinÇ
dc.creator.authorNiggemann, Bodo
dc.creator.authorNilsson, Gunnar
dc.creator.authorOllert, Markus
dc.creator.authorO’Mahony, Liam
dc.creator.authorO’Neil, Serena
dc.creator.authorPala, Gianni
dc.creator.authorPapi, Alberto
dc.creator.authorPassalacqua, Gianni
dc.creator.authorPerkin, Michael
dc.creator.authorPfaar, Oliver
dc.creator.authorPitsios, Constantinos
dc.creator.authorQuirce, Santiago
dc.creator.authorRaap, Ulrike
dc.creator.authorRaulf-Heimsoth, Monika
dc.creator.authorRhyner, Claudio
dc.creator.authorRobson-Ansley, Paula
dc.creator.authorAlves, Rodrigo R
dc.creator.authorRoje, Zeljka
dc.creator.authorRondon, Carmen
dc.creator.authorRudzeviciene, Odilija
dc.creator.authorRuëff, Franziska
dc.creator.authorRukhadze, Maia
dc.creator.authorRumi, Gabriele
dc.creator.authorSackesen, Cansin
dc.creator.authorSantos, Alexandra F
dc.creator.authorSantucci, Annalisa
dc.creator.authorScharf, Christian
dc.creator.authorSchmidt-Weber, Carsten
dc.creator.authorSchnyder, Benno
dc.creator.authorSchwarze, Jürgen
dc.creator.authorSenna, Gianenrico
dc.creator.authorSergejeva, Svetlana
dc.creator.authorSeys, Sven
dc.creator.authorSiracusa, Andrea
dc.creator.authorSkypala, Isabel
dc.creator.authorSokolowska, Milena
dc.creator.authorSpertini, Francois
dc.creator.authorSpiewak, Radoslaw
dc.creator.authorSprikkelman, Aline
dc.creator.authorSturm, Gunter
dc.creator.authorSwoboda, Ines
dc.creator.authorTerreehorst, Ingrid
dc.creator.authorToskala, Elina
dc.creator.authorTraidl-Hoffmann, Claudia
dc.creator.authorVenter, Carina
dc.creator.authorVlieg-Boerstra, Berber
dc.creator.authorWhitacker, Paul
dc.creator.authorWorm, Margitta
dc.creator.authorXepapadaki, Paraskevi
dc.creator.authorAkdis, Cezmi A
dc.identifier.doihttp://dx.doi.org/10.1186/2045-7022-2-21
dc.identifier.urnURN:NBN:no-51270
dc.type.documentTidsskriftartikkel
dc.type.peerreviewedPeer reviewed
dc.identifier.fulltextFulltext https://www.duo.uio.no/bitstream/handle/10852/47123/1/13601_2012_Article_291.pdf
dc.type.versionPublishedVersion
cristin.articleid21


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