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dc.contributor.authorAursnes, Ivar
dc.contributor.authorTvete, Fride I
dc.contributor.authorGaasemyr, Jorund
dc.contributor.authorNatvig, Bent
dc.date.accessioned2015-10-09T02:11:27Z
dc.date.available2015-10-09T02:11:27Z
dc.date.issued2006
dc.identifier.citationBMC Psychiatry. 2006 Nov 28;6(1):55
dc.identifier.urihttp://hdl.handle.net/10852/46705
dc.description.abstractBackground Following our previous publication we have received critical comments to our conclusions as well as new data that are strengthening our findings. Results With the new data, 11 suicide attempts among patients on paroxetine against 1 among patients on placebo, we found with a Bayesian technique that the posterior probability that medication with paroxetine is associated with an increased intensity per year of a suicide attempt is from 0.98 to 0.99, depending on the prior. We found that the comment to our article by GSK representatives contained errors, misunderstanding and unwillingness to accept Bayesian principles in the analysis of clinical trials. Conclusion We were in our previous publication, with preliminary data and a Bayesian approach, able to raise a concern that suicide attempts might be connected with the use of paroxetine. This suspicion has now been confirmed.
dc.language.isoeng
dc.rightsAursnes et al.
dc.rightsAttribution 2.0 Generic
dc.rights.urihttp://creativecommons.org/licenses/by/2.0/
dc.titleEven more suicide attempts in clinical trials with paroxetine randomised against placebo
dc.typeJournal article
dc.date.updated2015-10-09T02:11:27Z
dc.creator.authorAursnes, Ivar
dc.creator.authorTvete, Fride I
dc.creator.authorGaasemyr, Jorund
dc.creator.authorNatvig, Bent
dc.identifier.doihttp://dx.doi.org/10.1186/1471-244X-6-55
dc.identifier.urnURN:NBN:no-50873
dc.type.documentTidsskriftartikkel
dc.type.peerreviewedPeer reviewed
dc.identifier.fulltextFulltext https://www.duo.uio.no/bitstream/handle/10852/46705/1/12888_2006_Article_184.pdf
dc.type.versionPublishedVersion
cristin.articleid55


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