Hide metadata

dc.contributor.authorLarssen, Lene
dc.contributor.authorMedhus, Asle W
dc.contributor.authorHauge, Truls
dc.date.accessioned2015-10-09T01:02:57Z
dc.date.available2015-10-09T01:02:57Z
dc.date.issued2009
dc.identifier.citationBMC Gastroenterology. 2009 Jun 17;9(1):45
dc.identifier.urihttp://hdl.handle.net/10852/46306
dc.description.abstractBackground Malignant gastric outlet obstruction (GOO) is commonly seen in patients with advanced gastric-, pancreatic-, duodenal, hepatobiliary or metastatic malignancies. Ten to 25% of patients with pancreatic cancer will develop duodenal obstruction during the course of the disease. Duodenal stenting with self-expandable metal stents is an alternative treatment to surgical bypass procedures. Our aim was to review the published literature regarding treatment of malignant GOO with stents to reveal whether the information provided is sufficient to evaluate the clinical effects of this treatment Methods A literature search from 2000 – 2007 was conducted in Pub Med, Embase, and Cochrane library, combining the following search terms: duodenal stent, malignant duodenal obstruction, gastric outlet obstruction, SEMS, and gastroenteroanastomosis. All publications presenting data with ≥ 15 patients and only articles written in English were included and a review focusing on the following parameters were conducted: 1) The use of graded scoring systems evaluating clinical success; 2) Assessment of Quality of life (QoL) before and after treatment; 3) Information on stent-patency; 4) The use of objective criteria to evaluate the stent effect. Results 41 original papers in English were found; no RCT's. 16 out of 41 studies used some sort of graded scoring system. No studies had objectively evaluated QoL before or after stent treatment, using standardized QoL-questionnaires, 32/41 studies reported on stent patency and 9/41 performed an oral contrast examination after stent placement. Objective quantitative tests of gastric emptying had not been performed. Conclusion Available reports do not provide sufficient relevant information of the clinical outcome of duodenal stenting. In future studies, these relevant issues should be addressed to allow improved evaluation of the effect of stent treatment.
dc.language.isoeng
dc.rightsLarssen et al.
dc.rightsAttribution 2.0 Generic
dc.rights.urihttp://creativecommons.org/licenses/by/2.0/
dc.titleTreatment of malignant gastric outlet obstruction with stents: An evaluation of the reported variables for clinical outcome
dc.typeJournal article
dc.date.updated2015-10-09T01:02:57Z
dc.creator.authorLarssen, Lene
dc.creator.authorMedhus, Asle W
dc.creator.authorHauge, Truls
dc.identifier.doihttp://dx.doi.org/10.1186/1471-230X-9-45
dc.identifier.urnURN:NBN:no-50562
dc.type.documentTidsskriftartikkel
dc.type.peerreviewedPeer reviewed
dc.identifier.fulltextFulltext https://www.duo.uio.no/bitstream/handle/10852/46306/1/12876_2008_Article_337.pdf
dc.type.versionPublishedVersion
cristin.articleid45


Files in this item

Appears in the following Collection

Hide metadata

Attribution 2.0 Generic
This item's license is: Attribution 2.0 Generic