Browsing Kjemisk institutt by Author "Halskau, Øyvind"

Now showing items 1-3 of 3

  • Bioactive Metabolites of Marine Origin Have Unusual Effects on Model Membrane Systems 
    Jakubec, Martin; Totland, Christian; Rise, Frode; Chamgordani, Elahe Jafari; Paulsen, Britt; Maes, Louis; Matheeussen, An; Gundersen, Lise-Lotte; Halskau, Øyvind (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
    Marine sponges and soft corals have yielded novel compounds with antineoplastic and antimicrobial activities. Their mechanisms of action are poorly understood, and in most cases, little relevant experimental evidence is ...
  • Cholesterol-containing lipid nanodiscs promote an α-synuclein binding mode that accelerates oligomerization 
    Jakubec, Martin; Bariås, Espen; Furse, Samuel Robert; Govasli Larsen, Morten Andreas; George, Vinnit; Turcu, Diana Cornelia; Iashchishyn, Igor A.; Morozova-Roche, Ludmilla A.; Halskau, Øyvind (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
    Dysregulation of the biosynthesis of cholesterol and other lipids has been implicated in many neurological diseases, including Parkinson's disease. Misfolding of α‐synuclein (α‐Syn), the main actor in Parkinson's disease, ...
  • The biosynthesis of phospholipids is linked to the cell cycle in a model eukaryote 
    Vitova, Milada; Lanta, Vojtech; Cizkova, Maria; Jakubec, Martin; Rise, Frode; Halskau, Øyvind; Bisova, Katerina; Furse, Samuel Robert (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
    The structural challenges faced by eukaryotic cells through the cell cycle are key for understanding cell viability and proliferation. We tested the hypothesis that the biosynthesis of structural lipids is linked to the ...