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dc.date.accessioned2015-03-12T10:09:52Z
dc.date.available2015-03-12T10:09:52Z
dc.date.created2014-12-15T18:28:15Z
dc.date.issued2014
dc.identifier.citationWinger, Anette Kvarstein, Gunnvald Wyller, Vegard Bruun Sulheim, Dag Fagermoen, Frode Even Småstuen, Milada Cvancarova Helseth, Sølvi . Pain and pressure pain thresholds in adolescents with chronic fatigue syndrome and healthy controls: a cross-sectional study. BMJ Open. 2014, 4(10)
dc.identifier.urihttp://hdl.handle.net/10852/43118
dc.description.abstractObjectives: Although pain is a significant symptom in chronic fatigue syndrome (CFS), pain is poorly understood in adolescents with CFS. The aim of this study was to explore pain distribution and prevalence, pain intensity and its functional interference in everyday life, as well as pressure pain thresholds (PPT) in adolescents with CFS and compare this with a control group of healthy adolescents (HC). Methods: This is a case–control, cross-sectional study on pain including 120 adolescents with CFS and 39 HCs, aged 12–18 years. We measured pain frequency, pain severity and pain interference using self-reporting questionnaires. PPT was measured using pressure algometry. Data were collected from March 2010 until October 2012 as part of the Norwegian Study of Chronic Fatigue Syndrome in Adolescents: Pathophysiology and Intervention Trial. Results: Adolescents with CFS had significantly lower PPTs compared with HCs (p<0.001). The Pain Severity Score and the Pain Interference Score were significantly higher in adolescents with CFS compared with HCs (p<0.001). Almost all adolescents with CFS experienced headache, abdominal pain and/or pain in muscles and joints. Moreover, in all sites, the pain intensity levels were significantly higher than in HCs (p<0.001). Conclusions: We found a higher prevalence of severe pain among adolescents with CFS and lowered pain thresholds compared with HCs. The mechanisms, however, are still obscure. Large longitudinal population surveys are warranted measuring pain thresholds prior to the onset of CFS.en_US
dc.languageEN
dc.language.isoenen_US
dc.publisherBMJ Publishing Group
dc.relation.ispartofWinger, Anette (2015) Pain and health related quality of life in adolescents with chronic fatigue syndrome. A mixed method study. Doctoral thesis. http://urn.nb.no/URN:NBN:no-52117
dc.relation.urihttp://urn.nb.no/URN:NBN:no-52117
dc.rightsAttribution-NonCommercial 4.0 International
dc.rights.urihttp://creativecommons.org/licenses/by-nc/4.0/
dc.titlePain and pressure pain thresholds in adolescents with chronic fatigue syndrome and healthy controls: a cross-sectional studyen_US
dc.typeJournal articleen_US
dc.creator.authorWinger, Anette
dc.creator.authorKvarstein, Gunnvald
dc.creator.authorWyller, Vegard Bruun
dc.creator.authorSulheim, Dag
dc.creator.authorFagermoen, Frode Even
dc.creator.authorSmåstuen, Milada Cvancarova
dc.creator.authorHelseth, Sølvi
cristin.unitcode185,53,30,0
cristin.unitnameKlinikk for indremedisin og laboratoriefag
cristin.ispublishedtrue
cristin.fulltextoriginal
cristin.fulltextoriginal
cristin.qualitycode1
dc.identifier.cristin1185425
dc.identifier.bibliographiccitationinfo:ofi/fmt:kev:mtx:ctx&ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=BMJ Open&rft.volume=4&rft.spage=&rft.date=2014
dc.identifier.jtitleBMJ Open
dc.identifier.volume4
dc.identifier.pagecount9
dc.identifier.doihttp://dx.doi.org/10.1136/bmjopen-2014-005920
dc.identifier.urnURN:NBN:no-47507
dc.type.documentTidsskriftartikkelen_US
dc.type.peerreviewedPeer reviewed
dc.source.issn2044-6055
dc.identifier.fulltextFulltext https://www.duo.uio.no/bitstream/handle/10852/43118/1/BMJ%2BOpen-2014-Winger-.pdf
dc.type.versionPublishedVersion
cristin.articleide005920


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