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Now showing items 1-10 of 11
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2008)
Background
Multiple epigenetic and genetic changes have been reported in colorectal tumors, but few of these have clinical impact. This study aims to pinpoint epigenetic markers that can discriminate between ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2008)
Background
Tumor-derived aberrantly methylated DNA might serve as diagnostic biomarkers for cancer, but so far, few such markers have been identified. The aim of the present study was to investigate the ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2007)
Background
Despite the fact that metastases are the leading cause of colorectal cancer deaths, little is known about the underlying molecular changes in these advanced disease stages. Few have studied the ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2009)
Background
The ability to detect neoplasia-specific fusion genes is important not only in cancer research, but also increasingly in clinical settings to ensure that correct diagnosis is made and the optimal ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2007)
Background
Ovarian germ cell tumours (OGCTs) typically arise in young females and their pathogenesis remains poorly understood. We investigated the origin of malignant OGCTs and underlying molecular events ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2007)
Background
The epigenetics of ovarian carcinogenesis remains poorly described. We have in the present study investigated the promoter methylation status of 13 genes in primary ovarian carcinomas (n = 52) ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2004)
Background
Colorectal cancer (CRC) is one of the most common causes of cancer-related deaths in the Western world, and despite the fact that metastases are usually the ultimate cause of deaths, the knowledge ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2005)
Background
Recent studies have demonstrated that the NKX3.1 protein is commonly down-regulated in testicular germ cell tumors (TGCTs) and prostate carcinomas. The homeobox gene NKX3.1 maps to chromosome ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2006)
Background
In order to gain new insights into the molecular mechanisms involved in prostate cancer, we performed array-based comparative genomic hybridization (aCGH) on a series of 46 primary prostate ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2007)
Background
To assess the impact of polymorphisms in Glutathione S-transferase (GST) -P1, -M1, and -T1 on self-reported chemotherapy-induced long-term toxicities in testicular cancer survivors (TCSs).
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