In Norway, consumption of psychotropic drug is increasing concomitant with huge variations across the counties. The main purpose of this research is to analyze the regional variation of consumption of psychotropic drug and identify the responsible factors for these variations. Using eight-years, 2004-2011, panel data analysis techniques for 19 counties, we provided fixed effect model to analyze the effect of some selective explanatory variables and different counties on the use of psychotropic drug. Our main result shows that consumption of psychotropic drug responded positively with higher education, higher population density, taking social assistance, age group 35-44, age group 45-69, age group 70-79, and age group 80+ and negatively responded with higher temperature, non-Norwegian ethnicity, GP density, and unemployment rate. We also found a clear north south difference with respect to psychotropic drug consumption. People living in Southern part of Norway consumed more psychotropic drug than those live in the Northern part.