In vitro chondrogenesis. The role of microRNAs during differentiation and dedifferentiation
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AbstractList of papers. Papers I and II are removed from the thesis due to publisher restrictions.
Paper I: Human primary articular chondrocytes, chondroblasts-like cells, and dedifferentiated chondrocytes: differences in gene, microRNA, and protein expression and phenotype. Karlsen TA, Shahdadfar A, Brinchmann JE. Tissue Eng Part C Methods. 2011 Feb;17(2):219-27. doi:10.1089/ten.tec.2010.0200
Paper II: microRNA-140 regulates chondrogenic differentiation of human mesenchymal stem cells by post-transcriptional enhancement of chondrogenic molecules. Karlsen TA, Jakobsen RB*, Mikkelsen TS, Brinchmann JE. Submitted version. Published as: microRNA-140 targets RALA and regulates chondrogenic differentiation of human mesenchymal stem cells by translational enhancement of SOX9 and ACAN. Stem Cells and Development. Epud ahead of print Sep 24 2013. doi:10.1089/scd.2013.0209
Paper III: Liposome delivery of microRNA-145 to mesenchymal stem cells leads to immunological offtarget effects mediated by RIG-I. Karlsen TA, Brinchmann JE. Accepted version. Molecular Therapy, 2013 Jun;21(6):1169-81. doi:10.1038/mt.2013.55