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Now showing items 1-10 of 96
(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2016)
Objective Gut microbiota could influence gut, as well as hepatic and biliary immune responses. We therefore thoroughly characterised the gut microbiota in primary sclerosing cholangitis (PSC) compared with healthy controls ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2013)
Background Immigrants from South Asia to Western countries have a high prevalence of type 2 diabetes mellitus (T2DM). We explored pathogenic factors that might contribute to the high risk of T2DM in Pakistani immigrants ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)
Background: Co-infection with malaria and HIV increases the severity and mortality of both diseases, but the cytokine responses related to this co-infection are only partially characterised. The aim of this study was to ...
(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2014)
Blood pressure is a critical determinant of cardiovascular morbidity and mortality. It is affected by environmental factors, but has a strong heritable component. Despite recent large genome-wide association studies, few ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)
Epidemiological studies suggest a relationship between blood lipids and immune-mediated diseases, but the nature of these associations is not well understood. We used genome-wide association studies (GWAS) to investigate ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
Background
There is a lack of comprehensive patient-datasets regarding prevalence of severe hypertriglyceridemia (sHTG; triglycerides ≥10 mmol/L), frequency of co-morbidities, gene mutations, and gene ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)
Background COPD exacerbations accelerate disease progression.
Aims To examine if COPD characteristics and systemic inflammatory markers predict the risk for acute COPD exacerbation (AECOPD) frequency and duration.
Methods ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)
Despite recent medical advances, atherosclerosis is a global burden accounting for numerous deaths and hospital admissions. Immune-mediated inflammation is a major component of the atherosclerotic process, but earlier ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)
Objectives: Biomarkers for diagnosis and therapy efficacy in tuberculosis (TB) are requested. We have studied biomarkers that may differentiate between active and latent TB infection (LTBI), the influence of HIV infection ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)
Background Dilated cardiomyopathy is characterized by left ventricular dilatation and dysfunction. Inflammation and adverse remodeling of the extracellular matrix may be involved in the pathogenesis. Statins reduce levels ...