Browsing Institutt for klinisk medisin by Author "Zabirnyk, Arsenii"

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  • A Novel Ex Vivo Model of Aortic Valve Calcification. A Preliminary Report 
    Zabirnyk, Arsenii; Perez, Maria del Mar; Blasco, Marc; Stensløkken, Kåre-Olav; Ferrer, Miguel D.; Salcedo, Carolina; Vaage, Ingvar Jarle (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
    Background: No pharmacological treatment exists to prevent or stop the calcification process of aortic valves causing aortic stenosis. The aim of this study was to develop a robust model of induced calcification in whole ...
  • Models and Techniques to Study Aortic Valve Calcification in Vitro, ex Vivo and in Vivo. An Overview 
    Bogdanova, Mariia; Zabirnyk, Arsenii; Malashicheva, Anna; Semenova, Daria; Kvitting, John-Peder; Kaljusto, Mari-Liis; Perez, Maria del Mar; Kostareva, Anna; Stensløkken, Kåre-Olav; Sullivan, Gareth John; Rutkovskiy, Arkady; Vaage, Ingvar Jarle (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
    Aortic valve stenosis secondary to aortic valve calcification is the most common valve disease in the Western world. Calcification is a result of pathological proliferation and osteogenic differentiation of resident valve ...
  • SNF472, a novel anti-crystallization agent, inhibits induced calcification in an in vitro model of human aortic valve calcification 
    Zabirnyk, Arsenii; Ferrer, Miguel David; Bogdanova, Maria A; Perez, MM; Salcedo, C; Kaljusto, Mari-Liis; Kvitting, John Peder Escobar; Stensløkken, Kåre-Olav; Perello, Joan; Vaage, Ingvar Jarle (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
    The purpose of the present study was to investigate whether SNF472, the hexasodium salt of myo-inositol hexaphosphate (IP6 or phytate): 1. Inhibits induced calcification in cultured aortic valve interstitial cells (VIC) ...