Browsing Institutt for klinisk medisin by Title
Now showing items 5074-5093 of 5298
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)In the aftermath of terrorist attacks and disasters, public institutions play an important role in re-establishing safety and justice. However, little is known about the importance of institutional trust for victims’ ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)Background Globally, tuberculosis (TB) lasts a major public health concern. Using feasible strategies to estimate TB infectious periods is crucial. The aim of this study was to determine the magnitude of TB infectious ...
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(Doctoral thesis / Doktoravhandling, 2012)
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)Introduction Hypercoagulability in malignancy increases the risk of thrombosis, but is also involved in cancer progression. Experimental studies suggest that tissue factor (TF) and tissue factor pathway ...
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(Doctoral thesis / Doktoravhandling, 2020)Prostate cancer is the most frequently diagnosed cancer among Norwegian men. Currently available risk stratification tools are inadequate for differentiating between men who will develop a life-threatening disease that ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)CD4+ T cells can induce potent anti-tumor immune responses. Due to the lack of MHC class II expression in most cancer cells, antigen recognition occurs indirectly via uptake and presentation on tumor-infiltrating ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)Background The complement system is involved in pathogenesis of cardiovascular disease, and might play a role in accelerated atherogenesis in spondylarthropathies (SpA). Hence, we examined complement activation in SpA, and ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)Secretion of matrix metalloproteinases (MMPs) enables cancer cells to degrade extracellular matrix, thus promoting tumor invasion and metastasis. We have recently found that the endosomal protein WDFY2 serves as a gatekeeper ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)Although the first nanomedicine was clinically approved more than two decades ago, nanoparticles’ (NP) in vivo behavior is complex and the immune system’s role in their application remains elusive. At present, only ...
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(Doctoral thesis / Doktoravhandling, 2017)
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)Background Intratumoural T-cell infiltrate intensity cortes wrelaith clinical outcome in stage II/III colorectal cancer (CRC). We aimed to determine whether this association varies across this heterogeneous group. Me ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)Attentional deficits following stroke are common and pervasive, and are important predictors for functional recovery. Attentional functions comprise a set of specific cognitive processes allowing to attend, filter and ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)Background: Enterovirus-D68 (EV-D68) is a respiratory virus within the genus Enterovirus and the family of Picornaviridae. Genetically, it is closely related to rhinovirus that replicates in the respiratory tract and causes ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2013)Background TWIST1 plays a key role in EMT-mediated tumor invasion and metastasis. Since bone metastasis is a hallmark of advanced prostate cancer and is detected in at least 85% of patients who die of this ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)Patients with sickle cell disease (SCD) suffer from anemia and painful vaso-occlusive crisis (VOC) and sometimes need blood transfusions. Delayed hemolytic transfusion reaction (DHTR) is a rare life-threatening complication ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2011)Background Rett syndrome (RTT) is an X-linked dominant neurodevelopmental disorder, which is usually caused by de novo mutations in the MECP2 gene. More than 70% of the disease causing MECP2 mutations are ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2007)Background X-linked Charcot-Marie Tooth (CMT) is caused by mutations in the connexin32 gene that encodes a polypeptide which is arranged in hexameric array and form gap junctions. ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2010)Background The Charcot-Marie-Tooth (CMT) phenotype caused by mutation in the myelin protein zero (MPZ) gene varies considerably, from early onset and severe forms to late onset and milder forms. The mechanism ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)Early-onset preeclampsia has been linked to poor placentation and fetal growth restriction, whereas late-onset preeclampsia was suggested to result from maternal factors. We have proposed an alternative model, suggesting ...
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(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2017)Purpose: To study the effects of converting to aflibercept in accordance with a treat and extend (T&E) strategy in eyes with treatment resistant exudative agerelated macular degeneration (AMD). Methods: Two-year prospective ...