Browsing Institutt for klinisk medisin by Title
Now showing items 3059-3078 of 3254
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Toxic effects of mineral oil saturated hydrocarbons (MOSH) and relation to accumulation in rat liver (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2018)Humans are daily exposed to mineral oil saturated hydrocarbons (MOSH) from the diet. We exposed female Fischer 344 rats to a broad mixture and sub-fractions of MOSH. Chemical characterization of the MOSH mixture used and ...
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(Doctoral thesis / Doktoravhandling, 2017)Parasitten Toxoplasma gondii kan forårsake alvorlig fosterskade som fosterdød, hjerneskade og synsnedsettelse dersom en kvinne smittes mens hun er gravid. Er hun smittet før svangerskapet, har hun antistoffer som beskytter ...
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TP53 mutation status and gene expression profiles are powerful prognostic markers of breast cancer (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2007)Introduction Gene expression profiling of breast carcinomas has increased our understanding of the heterogeneous biology of this disease and promises to impact clinical care. The aim of this study was to ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2005)Background Ovarian carcinomas from 30 BRCA1 germ-line carriers of two distinct high penetrant founder mutations, 20 carrying the 1675delA and 10 the 1135insA, and 100 sporadic cases were characterized for ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)Background The pathophysiology and outcome of meningococcal septic shock is closely associated with the plasma level of N. meningitidis lipopolysaccharides (LPS, endotoxin) and the circulating level of ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)Background Single-cell micro-metastases of solid tumors often occur in the bone marrow. These disseminated tumor cells (DTCs) may resist therapy and lay dormant or progress to cause overt bone and visceral ...
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(Doctoral thesis / Doktoravhandling, 2014)
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2010)Background The present study compares the value of additional use of computer simulated heart sounds, to conventional bedside auscultation training, on the cardiac auscultation skills of 3rd year medical ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)Background The care situation for persons experiencing severe mental illness is often complex and demands good coordination, communication, and interpersonal relationships among those involved from the ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)Background: Sleep problems are common during pregnancy and in the postnatal period, but there is still a lack of longitudinal population-based studies assessing the quantity and quality of sleep in these women. The aim of ...
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(Doctoral thesis / Doktoravhandling, 2016)
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(Doctoral thesis / Doktoravhandling, 2016)
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(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2018)The human tympanic membrane (TM) has a thin outer epidermal layer which plays an important role in TM homeostasis and ear health. The specialised cells of the TM epidermis have a different physiology compared to normal ...
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(Journal article / Tidsskriftartikkel / SubmittedVersion, 2018)The tissue dendritic cell (DC) compartment is heterogeneous, and the ontogeny and functional specialization of human tissue conventional DC (cDC) subsets and their relationship with monocytes is unresolved. Here we identify ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)The aim of the present study was to investigate the molecular mechanisms underlying activation of cell death pathways using genome-wide transcriptional analysis in human limbal epithelial cell (HLEC) cultures following ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)The oxidation resistance gene 1 (OXR1) is crucial for protecting against oxidative stress; however, its molecular function is unknown. We employed RNA sequencing to examine the role of human OXR1 for genome wide transcription ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)We present the spatiotemporal metabolic differentiation of yeast cell subpopulations from upper, lower, and margin regions of colonies of different ages, based on comprehensive transcriptomic analysis. Furthermore, the ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)Background Biological interpretation of DNA microarray data may differ depending on underlying assumptions and statistical tests of bioinformatics tools used. We used Gene Set Enrichment Analysis (GSEA) and ...
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(Doctoral thesis / Doktoravhandling, 2012)
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)Horizontal transfer of antibiotic resistance determinants contributes to dissemination of antibiotic resistance. Such transfer of resistance genes within the human gut has been documented in some in vivo studies. The present ...