Browsing Institutt for klinisk medisin by Title
Now showing items 21-40 of 2047
-
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2005)Background As farming of Atlantic salmon is growing as an aquaculture enterprise, the need to identify the genomic mechanisms for specific traits is becoming more important in breeding and management of the ...
-
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)Background The aim of this study was to investigate whether childhood trauma was associated with more severe clinical features in patients with first-episode psychosis, both at the initial assessment and ...
-
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2013)The recently discovered HEAT-like repeat (HLR) DNA glycosylase superfamily is widely distributed in all domains of life. The present bioinformatics and phylogenetic analysis shows that HLR DNA glycosylase superfamily members ...
-
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2012)Background The major rate-limiting enzyme for de novo cholesterol synthesis is 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGCR). HMGCR is sterically inhibited by statins, the most commonly prescribed ...
-
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)Background Advances in sequencing technologies and bioinformatics have made the analysis of microbial communities almost routine. Nonetheless, the need remains to improve on the techniques used for gathering ...
-
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2012)Background Up to date information on poisoning trends is important. This study reports the epidemiology of all hospitalized acute poisonings in Oslo, including mortality, follow-up referrals, and whether ...
-
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)Background Personalized therapy considering clinical and genetic patient characteristics will further improve breast cancer survival. Two widely used treatments, chemotherapy and radiotherapy, can induce ...
-
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)Background Depression in pregnancy increases the risk of complications for mother and child. Few studies are done in ethnic minorities. We wanted to identify the prevalence of depression in pregnancy and ...
-
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2011)Background Ipilimumab, a fully human monoclonal antibody that blocks cytotoxic T-lymphocyte antigen-4, has demonstrated an improvement in overall survival in two phase III trials of patients with advanced ...
-
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
-
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)Background Quality control after phonosurgery is important and may be time consuming. Often questionnaires focusing on quality of life are applied. We aimed at investigating the use of organ specific symptoms, ...
-
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2008)Background There is variation in the number of response alternatives used within health-related questionnaires. This study compared a four-and a five-point scale version of the Norwegian Function Assessment ...
-
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)We report two unrelated patients with overlapping chromosome 2q13 deletions (patient 1 in chr2:111415137-113194067 bp and patient 2 in chr2:110980342-113007823 bp, hg 19). Patient 1 presents with developmental delay, ...
-
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)The concept of recovery has gained increasing attention and many mental health systems have taken steps to move towards more recovery oriented practice and service structures. This article represents a description of current ...
-
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)Background Droplet digital PCR (ddPCR) allows absolute quantification of nucleic acids and has potential for improved non-invasive detection of DNA methylation. For increased precision of the methylation ...
-
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)Objective: To systematically review studies of cognitive remediation therapy (CRT) for anorexia nervosa (AN), and to discuss findings with references to clinical practice and future research. Method: The literature was ...
-
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2013)Background Shoulder pain is a common condition with prevalence estimates of 7–26% and the associated disability is multi-faceted. For functional assessments in clinic and research, a number of condition-specific ...
-
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2010)Background It is important to obtain greater insight into health-related quality of life (HRQL) of injury patients in order to document people's pathways to recovery and to quantify the impact of injury on ...
-
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)Background Physical exercise has been shown to improve asthma symptoms, QoL, exercise capacity, bronchial hyperresponsiveness and lung function and is recommended as a supplementary treatment to pharmacotherapy ...
-
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)Background Severe sepsis and septic shock are common in intensive care and carry high mortality rates. In patients with Gram-negative infections, early and extensive removal of endotoxin may limit the ...