Now showing items 1601-1620 of 4581

  • Schalekamp-Timmermans, Sarah; Arends, Lidia R; Alsaker, Elin Hilde Roti; Chappell, Lucy; Hansson, Stefan; Harsem, Nina Kittelsen; Jälmby, Maya; Jeyabalan, Arundhathi; Laivuori, Hannele; Lawlor, Debbie A; Macdonald-Wallis, Corrie; Magnus, Per; Myers, Jenny; Olsen, Jørn; Poston, Lucilla; Redman, Christopher W; Staff, Anne Cathrine; Villa, Pia; Roberts, James M; Steegers, Eric A (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
    Background: Pre-eclampsia (PE) is a major pregnancy disorder complicating up to 8% of pregnancies. Increasing evidence indicates a sex-specific interplay between the mother, placenta and fetus. This may lead to different ...
  • Stenshorne, Ida; Rasmussen, Magnhild; Salvanos, Panagiotis; Tallaksen, Chantal M E; Bindoff, Laurence A; Koht, Jeanette (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
    Background CAPOS (Cerebellar ataxia, Areflexia, Pes cavus, Optic atrophy and Sensorineural hearing loss) syndrome is caused by the heterozygous mutation, c.2452G > A, in the ATP1A3 gene. Other mutations ...
  • Rand, Kim; Dahl, Fredrik A; Viana, Joe; Rønning, Ole M; Faiz, Kashif W; Barra, Mathias (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
    Background Stroke incidence rates have fallen in high-income countries over the last several decades, but findings regarding the trend over recent years have been mixed. The aim of the study was to describe ...
  • Hessmann, E; Patzak, MS; Klein, L; Chen, N; Kari, V; Ramu, I; Bapiro, TE; Frese, KK; Gopinathan, A; Richards, FM; Jodrell, DI; Verbeke, Caroline Sophie; Li, X; Heuchel, Rainer; Löhr, JM; Johnsen, SA; Gress, TM; Ellenrieder, V; Neesse, A (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
    Desmoplasia and hypovascularity are thought to impede drug delivery in pancreatic ductal adenocarcinoma (PDAC). However, stromal depletion approaches have failed to show clinical responses in patients. Here, we aimed to ...
  • Lyngbakken, Magnus Nakrem; Pervez, Mohammad Osman; Brynildsen, Jon; Pedersen, Marit Holmefjord; Sølvernes, Janne; Christensen, Geir Arve; Høiseth, Arne Didrik; Omland, Torbjørn; Røsjø, Helge (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2017)
    Background Circulating fibroblast growth factor 23 (FGF23) concentrations have been linked to left ventricular remodeling and unfavorable cardiovascular outcomes, but whether FGF23 is associated with heart failure (HF) ...
  • Seip, Kotryna; Fleten, Karianne G.; Barkovskaya, Anna; Nygaard, Vigdis; Haugen, Mads H.; Engesæter, Birgit Ø.; Mælandsmo, Gunhild M.; Prasmickaite, Lina (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
    The knowledge on how tumor-associated stroma influences efficacy of anti-cancer therapy just started to emerge. Here we show that lung fibroblasts reduce melanoma sensitivity to the BRAF inhibitor (BRAFi) vemurafenib only ...
  • Rehn, Marius (Doctoral thesis / Doktoravhandling, 2012)
  • Hausken, John; Rydenfelt, Kristina Elisabeth; Horneland, Rune; Ullensvang, Kyrre; Kjøsen, Gisle; Tønnessen, Tor Inge; Haugaa, Håkon (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
    Background Standard of care for postoperative analgesia after pancreas transplant has been thoracic epidural analgesia (TEA). A high incidence of venous graft thrombosis necessitated a change to a more aggressive ...
  • Eskeland, Sigrun Losada; Brunborg, Cathrine; Seip, Birgitte Karen Berggreen; Wiencke, Kristine; Hovde, Øistein; Owen, Tanja; Skogestad, Erik; Huppertz-Hauss, Gert; Halvorsen, Fred-Arne; Garborg, Kjetil Kjeldstad; Aabakken, Lars; de Lange, Thomas (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
    Objective To create and validate an objective and reliable score to assess referral quality in gastroenterology. Design An observational multicentre study. Setting and participants 25 gastroenterologists participated in ...
  • Foss, Stein; Nordheim, Espen; SØRENSEN, DAG WENDELBO; Syversen, Torgunn Bø; Midtvedt, Karsten; Åsberg, Anders; Dahl, Thorleif; Bakkan, Per Arne; Foss, Aksel; Geiran, Odd; Fiane, Arnt E; Line, Pål Dag (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
    Background: Donation after circulatory death (DCD) can increase the pool of available organs for transplantation. This pilot study evaluates the implementation of a controlled DCD (cDCD) protocol using normothermic regional ...
  • Holmen, Sigve Dhondup; Kleppa, Elisabeth; Lillebø, Kristine; Pillay, Pavitra; van Lieshout, Lisette; Taylor, Myra; Albregtsen, Fritz; Vennervald, Birgitte Jyding; Onsrud, Mathias; Kjetland, Eyrun Floerecke (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)
    Schistosoma haematobium causes female genital schistosomiasis (FGS), which is a poverty-related disease in sub-Saharan Africa. Furthermore, it is co-endemic with human immunodeficiency virus (HIV), and biopsies from genital ...
  • Fuglesang, Hendrik Frølich; Flugsrud, Gunnar B; Randsborg, Per-Henrik; Hammer, Ola-Lars; Utvåg, Stein-Erik (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
    Background: Surgical management of completely displaced midshaft fractures of the clavicle is becoming more frequent, although long-term follow-up with Level-I evidence is scarce. Plate fixation (PF) of comminuted fractures ...
  • Rigó, István Zoltán (Doctoral thesis / Doktoravhandling, 2017)
    Laceration of finger flexor tendons is a common injury. One in five patients do not achieve good function after treatment. This thesis based on four publications aims to improve the functional results. In the first study ...
  • Indrebø, Marianne Müller (Doctoral thesis / Doktoravhandling, 2020)
    The Fontan procedure has revolutionized the treatment of univentricular hearts. However, it is associated with severe complications related to altered transcapillary fluid balance. Fluid accumulation with edema formation ...
  • Rut, Wioletta; Nielsen, Nis Valentin; Czarna, Justyna; Poreba, Marcin; Kanse, Sandip; Drag, Marcin (Journal article / Tidsskriftartikkel / SubmittedVersion, 2019)
    The zymogen form of circulating Factor VII activating protease (FSAP) is activated by histones that are released as a consequence of tissue damage or excessive inflammation. This is likely to have consequences in a number ...
  • Heir, Stig (Doctoral thesis / Doktoravhandling, 2011)
    In comparing four patient groups awaiting knee surgery treatment, patients with focal cartilage defects in their knees presented major problems with pain and functional impairment, their quality of life evaluated by KOOS ...
  • Randsborg, Per-Henrik; Brinchmann, Jan; Løken, Sverre; Hanvold, Heidi A; Aae, Tommy F; Årøen, Asbjørn (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
    Background Focal cartilage injuries in the knee might have devastating effect due to the predisposition of early onset osteoarthritis. Various surgical treatment options are available, however no statistically ...
  • Grytli, Helene Hartvedt (Doctoral thesis / Doktoravhandling, 2013)
  • Ruddox, Vidar; Norum, Ingvild B; Stokke, Thomas M; Edvardsen, Thor; Otterstad, Jan E (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
    Background Focus Cardiac Ultrasound (FoCUS) performed by internal medicine residents on call with 2 h of training can provide a means for ruling out cardiac disease, but with poor sensitivity. The purpose ...
  • Rothwell, Simon; Chinoy, Hector; Lamb, Janine A.; Miller, Frederick W.; Rider, Lisa G.; Wedderburn, Lucy R.; McHugh, Neil J.; Mammen, Andrew L.; Betteridge, Zoë E.; Tansley, Sarah L.; Bowes, John; Vencovsky, Jiří; Deakin, Claire T.; Dankó, Katalin; Vidya, Limaye; Selva-O'Callaghan, Albert; Pachman, Lauren M.; Reed, Ann M.; Molberg, Øyvind; Benveniste, Olivier; Mathiesen, Pernille R.; Radstake, Timothy R.D.J.; Doria, Andrea; De Bleecker, Jan; Lee, Annette T.; Hanna, Michael G.; Machado, Pedro M.; Ollier, William E.; Gregersen, Peter K.; Padyukov, Leonid; O'Hanlon, Terrance P.; Cooper, Robert G.; Lundberg, Ingrid E (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
    Idiopathic inflammatory myopathies (IIM) are a spectrum of rare autoimmune diseases characterised clinically by muscle weakness and heterogeneous systemic organ involvement. The strongest genetic risk is within the major ...