Now showing items 1559-1578 of 3232

  • Rydbeck, Halfdan (Doctoral thesis / Doktoravhandling, 2013)
    High throughput technologies, like next generation sequencing, in combination with assays for probing epigenetic marks, have made it possible to map the epigenetic landscapes of cell types. With the new information the ...
  • Brodtkorb, Marianne (Doctoral thesis / Doktoravhandling, 2014)
  • George, Julie; Walter, Vonn; Peifer, Martin; Alexandrov, Ludmil B.; Seidel, Danila; Leenders, Frauke; Maas, Lukas; Müller, Christian; Dahmen, Ilona; Delhomme, Tiffany M.; Ardin, Maude; Leblay, Noemie; Byrnes, Graham; Sun, Ruping; De Reynies, Aurélien; McLeer-Florin, Anne; Bosco, Graziella; Malchers, Florian; Menon, Roopika; Altmüller, Janine; Becker, Christian; Nürnberg, Peter; Achter, Viktor; Lang, Ulrich; Schneider, Peter M.; Bogus, Magdalena; Soloway, Matthew G.; Wilkerson, Matthew D.; Cun, Yupeng; McKay, James D.; Moro-Sibilot, Denis; Brambilla, Christian G.; Lantuejoul, Sylvie; Lemaitre, Nicolas; Soltermann, Alex; Weder, Walter; Tischler, Verena; Brustugun, Odd Terje; Lund-Iversen, Marius; Helland, Åslaug; Solberg, Steinar; Ansén, Sascha; Wright, Gavin; Solomon, Benjamin; Roz, Luca; Pastorino, Ugo; Petersen, Iver; Clement, Joachim H.; Sänger, Jörg; Wolf, Jürgen; Vingron, Martin; Zander, Thomas; Perner, Sven; Travis, William D.; Haas, Stefan A.; Olivier, Magali; Foll, Matthieu; Büttner, Reinhard; Hayes, David Neil; Brambilla, Elisabeth; Fernandez-Cuesta, Lynnette; Thomas, Roman K. (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
    Pulmonary large-cell neuroendocrine carcinomas (LCNECs) have similarities with other lung cancers, but their precise relationship has remained unclear. Here we perform a comprehensive genomic (n = 60) and transcriptomic ...
  • Matzaraki, Vasiliki; Gresnigt, Mark S; Jaeger, Martin; Ricaño-Ponce, Isis; Johnson, Melissa D; Oosting, Marije; Franke, Lude; Withoff, Sebo; Perfect, John R; Joosten, Leo AB; Kullberg, Bart Jan; van de Veerdonk, Frank; Jonkers, Iris; Li, Yang; Wijmenga, Tjitske Nienke; Netea, Mihai G; Kumar, Vinod (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
    Candidaemia is a bloodstream infection caused by Candida species that primarily affects specific groups of at-risk patients. Because only small candidaemia patient cohorts are available, classical genome wide association ...
  • Batmanov, Kirill; Wang, Wei; Bjørås, Magnar; Delabie, Jan; Wang, Junbai (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
    The contribution of mutations in regulatory regions to tumorigenesis has been the subject of many recent studies. We propose a new framework for integrative analysis of genome-wide sequencing data by considering diverse ...
  • Kaasa, Stein; Knudsen, Anne Kari; Lundeby, Tonje; Loge, Jon Håvard (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2017)
    With the groundbreaking work of three Milan professors—Bonadonna, Veronesi, and Ventafridda—in the 1980s as the starting point, this article aims to shed light on the potential benefits of a closer and more formal integration ...
  • de Lange, Thomas; Larsen, Stig; Aabakken, Lars (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2004)
    Background Endoscopic findings are essential in evaluating the disease activity in ulcerative colitis. The aim of this study was to evaluate how endoscopists assess individual endoscopic features of mucosal ...
  • Lee, Sindre; Norheim, Frode; Gulseth, Hanne Løvdal; Langleite, Torgrim Mikal; Kolnes, Kristoffer Jensen; Tangen, Daniel S.; Stadheim, Hans Kristian; Gilfillan, Gregor Duncan; Holen, Torgeir; Birkeland, Kåre I.; Jensen, Jørgen; Drevon, Christian A (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
    The hepatokine fetuin‐A can together with free fatty acids (FFAs) enhance adipose tissue (AT) inflammation and insulin resistance via toll‐like receptor 4 (TLR4). Although some of the health benefits of exercise can be ...
  • Hedström, Anna Karin; Katsoulis, Michail; Hössjer, Ola; Bomfim, Izaura L.; Oturai, Annette; Søndergaard, Helle Bach; Sellebjerg, Finn; Ullum, Henrik; Thørner, Lise Wegner; Gustavsen, Marte Wendel; Harbo, Hanne Flinstad; Obradovic, Dragana; Gianfrancesco, Milena A.; Barcellos, Lisa F.; Schaefer, Catherine A.; Hillert, Jan; Kockum, Ingrid; Olsson, Tomas; Alfredsson, Lars (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
    Interactions between environment and genetics may contribute to multiple sclerosis (MS) development. We investigated whether the previously observed interaction between smoking and HLA genotype in the Swedish population ...
  • Sand, Kine Marita Knudsen; Bern, Malin C.; Nilsen, Jeannette; Dalhus, Bjørn; Gunnarsen, Kristin Støen; Cameron, Jason; Grevys, Algirdas; Bunting, Karen; Sandlie, Inger; Andersen, Jan Terje (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)
    Albumin is an abundant blood protein that acts as a transporter of a plethora of small molecules like fatty acids, hormones, toxins, and drugs. In addition, it has an unusual long serum half-life in humans of nearly 3 ...
  • Vaskinn, Anja; Abu-Akel, Ahmad (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2018)
    Objective: Autism and schizophrenia are characterized by impairments in social cognition and functioning. They can co-occur at both the trait/symptom and diagnostic levels. We investigated the concurrent effect of autism ...
  • Eiding, Helge; Kongsgaard, Ulf E; Braarud, Anne-Cathrine (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
    Background No consensus based national standard for interhospital transports of critically ill patients exists in Norway. The local hospitals are responsible for funding, organizing and performing these ...
  • Gregersen, Ida; Sandanger, Øystein; Askevold, Erik Tandberg; Sagen, Ellen Lund; Yang, Kuan; Holm, Sverre; Pedersen, Turid Margrethe; Skjelland, Mona; Krohg-Sørensen, Kirsten; Hansen, Trond Vidar; Dahl, Tuva Børresdatter; Otterdal, Kari; Espevik, Terje; Aukrust, Pål; Yndestad, Arne; Halvorsen, Bente (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
    Aim: Interleukin-27 (IL-27) is involved in different inflammatory diseases; however, its role in atherosclerosis is unclear. In this study we investigated the expression of IL-27 and its receptor in patients with carotid ...
  • Stav-Noraas, Tor Espen (Doctoral thesis / Doktoravhandling, 2018)
  • Ofstad, Anne P; Gullestad, Lars; Orvik, Elsa; Aakhus, Svend; Endresen, Knut; Ueland, Thor; Aukrust, Pål; Fagerland, Morten W; Birkeland, Kåre I; Johansen, Odd E (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2013)
    Background Novel and robust cardiovascular (CV) markers are needed to improve CV morbidity and mortality risk prediction in type 2 diabetes (T2D). We assessed the long term predictive value of 4 novel CV ...
  • Eftang, Lars L; Esbensen, Ying; Tannæs, Tone M; Bukholm, Ida R; Bukholm, Geir (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2012)
    Background The association between Helicobacter pylori infection and upper gastrointestinal disease is well established. However, only a small fraction of H. pylori carriers develop disease, and there are ...
  • Claassen, Y H M; Bastiannet, E; Hartgrink, H H; Dikken, J L; de Steur, W O; Slingerland, M; Verhoeven, R H A; van Eycken, Elizabeth; de Schutter, H; Lindblad, M; Hedberg, J; Johnson, Egil; Hjortland, G O; Jensen, L S; Larsson, H J; Koessler, T; Chevallay, M; Allum, W H; van de Velde, C J H (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
    Background: In the randomized Asian REGATTA trial, no survival benefit was shown for additional gastrectomy over chemotherapy alone in patients with advanced gastric cancer with a single incurable factor, thereby discouraging ...
  • Laventhal, Naomi; Verhagen, Eduard; Hansen, Thor Willy Ruud; Dempsey, Eugene; Davis, Peter Graham; Musante, Gabriel; Wiles, Alison; Meadow, Willliam; Janvier, Annie (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2017)
    OBJECTIVE: Ethically and legally, assertions that resuscitation is in a patient’s best interest should be inversely correlated with willingness to forego intensive care (and accept comfort care) at the surrogate’s request. ...
  • Stensland, Synne; Thoresen, Siri; Wentzel-Larsen, Tore; Dyb, Grete (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2014)
    Aims:Overweight and obesity in children and adolescents are major public health challenges associated with psychosocial adversity and unfavourable lifestyle. Exposure to interpersonal violence, such as sexual abuse, violence ...
  • Grinde, Maria T; Skrbo, Nirma; Moestue, Siver A; Rødland, Einar A; Borgan, Eldrid; Kristian, Alexandr; Sitter, Beathe; Bathen, Tone F; Børresen-Dale, Anne-Lise; Mælandsmo, Gunhild M; Engebraaten, Olav; Sørlie, Therese; Marangoni, Elisabetta; Gribbestad, Ingrid S (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)
    Introduction Dysregulated choline metabolism is a well-known feature of breast cancer, but the underlying mechanisms are not fully understood. In this study, the metabolomic and transcriptomic characteristics ...