Now showing items 1161-1180 of 3101

  • Micci, Francesca; Haugom, Lisbeth; Abeler, Vera M; Davidson, Ben; Tropé, Claes G; Heim, Sverre (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)
    Background It is known that all tumors studied in sufficient number to draw conclusions show characteristic/specific chromosomal rearrangements, and the identification of these chromosomes and the genes ...
  • Friis-Ottessen, Mariann (Doctoral thesis / Doktoravhandling, 2015)
    Ulcerative colitis (UC) is an inflammatory bowel disease, associated with increased lifetime risk of developing colorectal cancer. UC-associated cancers progress through increasing levels of dysplasia, accompanied by ...
  • Kirkhus, Lene; Saltyte Benth, Jurate; Kristjansson, Siri Rostoft; Grønberg, Bjørn Henning; Hjermstad, Marianne Jensen; Selbæk, Geir; Wyller, Torgeir Bruun; Harneshaug, Magnus; Jordhøy, Marit Slaaen (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
    Background: Frailty is a syndrome associated with increased vulnerability and an important predictor of outcomes in older cancer patients. Systematic assessments to identify frailty are seldom applied, and oncologists’ ...
  • Nilssen, Esben A; Synnes, Marianne; Tvegård, Tonje; Vebø, Heidi; Boye, Erik; Grallert, Beáta (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2004)
    Background Checkpoint mechanisms prevent cell cycle transitions until previous events have been completed or damaged DNA has been repaired. In fission yeast, checkpoint mechanisms are known to regulate ...
  • Holter, Marianne T. S.; Ness, Ottar; Johansen, Ayna Beate; Brendryen, Håvar (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
    A promising tool for bettering people’s health is eHealth (or “mHealth”) programs: fully automated, web-based health interventions. However, we know surprisingly little about eHealth’s working mechanisms. One possible ...
  • Eftang, Lars L; Klajic, Jovana; Kristensen, Vessela N; Tost, Jörg; Esbensen, Qin Y; Blom, Gustav P; Bukholm, Ida R K; Bukholm, Geir (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
    Background A large number of epigenetic alterations has been found to be implicated in the etiology of gastric cancer. We have studied the DNA methylation status of 27 500 gene promoter regions in 24 gastric ...
  • Melsom, Elin Maria Caroline Bull; Ørstavik, Øivind; Osnes, Jan-Bjørn; Skomedal, Tor; Levy, Finn Olav; Krobert, Kurt Allen (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)
    Background and purpose Despite the view that only β2- as opposed to β1-adrenoceptors (βARs) couple to Gi, some data indicate that the β1AR-evoked inotropic response is also influenced by the inhibition of Gi. Therefore, ...
  • Martelletti, Paolo; Lampl, Christian; Russell, Michael-Bjorn; Mitsikostas, Dimos-Dimitrios (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)
  • Nordengen, Kaja; Kirsebom, Bjørn-Eivind; Henjum, Kristi; Selnes, Per; Gísladóttir, Berglind; Wettergreen, Marianne; Torsetnes, Silje B; Grøntvedt, Gøril R; Waterloo, Knut K; Aarsland, Dag; Nilsson, Lars N G; Fladby, Tormod (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
    Background Neuronal and glial cell interaction is essential for synaptic homeostasis and may be affected in Alzheimer’s disease (AD). We measured cerebrospinal fluid (CSF) neuronal and glia markers along ...
  • Nyman, Tuula Anneli (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
    Gram-negative bacteria are associated with a wide spectrum of infectious diseases in humans. Inflammasomes are cytosolic protein complexes that are assembled when the cell encounters pathogens or other harmful agents. The ...
  • Askautrud, Hanne Arenberg; Gjernes, Elisabet; Gunnes, Gjermund; Sletten, Marit; Ross, D. T.; Børresen-Dale, Anne-Lise; Iversen, Nina; Tranulis, Michael A.; Frengen, Eirik (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)
    N-myc downstream-regulated gene 1 (NDRG1) is induced by cellular stress such as hypoxia and DNA damage, and in humans, germ line mutations cause Charcot-Marie-Tooth disease. However, the cellular roles of NDRG1 are not ...
  • Fensgård, Øyvind (Doctoral thesis / Doktoravhandling, 2010)
    The genomes of all animals are constantly challenged by exogenous and endogenous sources of DNA damaging agents. UV radiation, chemicals, pollutants, and by-products of the cells’ own metabolism may damage the genetic ...
  • Pourteymour, Shirin; Eckardt, Kristin; Holen, Torgeir; Langleite, Torgrim Mikal; Lee, Sindre; Jensen, Jørgen; Birkeland, Kåre I.; Drevon, Christian A; Hjorth, Marit (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
    Objective: Skeletal muscle is an important secretory organ, producing and releasing numerous myokines, which may be involved in mediating beneficial health effects of physical activity. More than 100 myokines have been ...
  • Naghavi, Mohsen; Abajobir, Amanuel Alemu; Abbafati, Cristiana; Abbas, Kaja M.; Abd-Allah, Foad; Abera, Semaw Ferede; Aboyans, Victor; Adetokunboh, Olatunji; Ärnlöv, Johan; Afshin, Ashkan; Agrawal, Anurag; Kiadaliri, Aliasghar Ahmad; Ahmadi, Alireza; Ahmed, Muktar Beshir; Aichour, Amani Nidhal; Aichour, Ibtihel; Aichour, Miloud Taki Eddine; Aiyar, Sneha; Al-Eyadhy, Ayman; Alahdab, Fares; Al-Aly, Ziyad; Alam, Khurshid; Alam, Noore; Alam, Tahiya; Alene, Kefyalew Addis; Ali, Syed Danish; Alizadeh-Navaei, Reza; Alkaabi, Juma M.; Alkerwi, Ala'a; Alla, Francois; Allebeck, Peter; Allen, Christine; Al-Raddadi, Rajaa; Alsharif, Ubai; Altirkawi, Khalid A.; Alvis-Guzman, Nelson; Amare, Azmeraw T.; Amini, Erfan; Ammar, Walid; Amoako, Yaw Ampem; Anber, Nahla; Andersen, Hjalte H.; Andrei, Catalina Liliana; Androudi, Sofia; Ansari, Hossein; Antonio, Carl Abelardo T.; Anwari, Palwasha; Arora, Megha; Artaman, Al; Aryal, Krishna Kumar; Asayesh, Hamid; Asgedom, Solomon W.; Atey, Tesfay Mehari; Avila-Burgos, Leticia; Avokpaho, Euripide Frinel G. Arthur; Awasthi, Ashish; Ellingsen, Christian Lycke; Hailu, Alemayehu; Knudsen, Ann Kristin; Vollset, Stein Emil; Weiderpass, Elisabete (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
    Summary Background Monitoring levels and trends in premature mortality is crucial to understanding how societies can address prominent sources of early death. The Global Burden of Disease 2016 Study (GBD 2016) provides ...
  • Hay, Simon I.; Abajobir, Amanuel Alemu; Abate, Kalkidan Hassen; Abbafati, Cristiana; Abbas, Kaja M.; Abd-Allah, Foad; Abdulle, Abdishakur M.; Abebo, Teshome Abuka; Abera, Semaw Ferede; Aboyans, Victor; Abu-Raddad, Laith J.; Ackerman, Ilana N.; Aryal, Krishna Kumar; Hailu, Alemayehu; Htet, Aung Soe; Knudsen, Ann Kristin; Kisa, Adnan; Norheim, Ole Frithjof; Skirbekk, Vegard Fykse; Vollset, Stein Emil; Weiderpass, Elisabete (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
    METHODS: We used results from the Global Burden of Diseases, Injuries, and Risk Factors Study 2016 for all-cause mortality, cause-specific mortality, and non-fatal disease burden to derive HALE and DALYs by sex for 195 ...
  • Vos, Theo; Abajobir, Amanuel Alemu; Abbafati, Cristiana; Abbas, Kaja M.; Abate, Kalkidan Hassen; Abd-Allah, Foad; Abdulle, Abdishakur M.; Abebo, Teshome Abuka; Abera, Semaw Ferede; Aboyans, Victor; Abu-Raddad, Laith J.; Ackerman, Ilana N.; Adamu, Abdu Abdullahi; Adetokunboh, Olatunji; Afarideh, Mohsen; Afshin, Ashkan; Agarwal, Sanjay Kumar; Aggarwal, Rakesh; Agrawal, Anurag; Agrawal, Sutapa; Kiadaliri, Aliasghar Ahmad; Ahmadieh, Hamid; Ahmed, Muktar Beshir; Aichour, Amani Nidhal; Aichour, Ibtihel; Aichour, Miloud Taki Eddine; Aiyar, Sneha; Akinyemi, Rufus Olusola; Akseer, Nadia; Al Lami, Faris Hasan; Alahdab, Fares; Al-Aly, Ziyad; Alam, Khurshid; Alam, Noore; Alam, Tahiya; Alasfoor, Deena; Alene, Kefyalew Addis; Ali, Raghib; Alizadeh-Navaei, Reza; Alkerwi, Ala'a; Alla, Francois; Allebeck, Peter; Allen, Christine; Al-Maskari, Fatma; Al-Raddadi, Rajaa; Alsharif, Ubai; Alsowaidi, Shirina; Altirkawi, Khalid A.; Amare, Azmeraw T.; Amini, Erfan; Aryal, Krishna Kumar; Htet, Aung Soe; Kisa, Adnan; Knudsen, Ann Kristin; Tollånes, Mette Christophersen; Skirbekk, Vegard Fykse; Steiner, Timothy J.; Stovner, Lars Jacob; Vollset, Stein Emil; Weiderpass, Elisabete; Hailu, Alemayehu (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
    BACKGROUND: As mortality rates decline, life expectancy increases, and populations age, non-fatal outcomes of diseases and injuries are becoming a larger component of the global burden of disease. The Global Burden of ...
  • Paunas, Teodora I F; Finne, Kenneth; Leh, Sabine; Marti, Hans-Peter; Mollnes, Tom E; Berven, Frode; Vikse, Bjørn E (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
    Background The clinical course of IgA nephropathy (IgAN) is variable and complement activation may predict prognosis. The present study investigated whether glomerular abundance of complement proteins ...
  • Helseth, Ragnhild; Knudsen, Eva C; Eritsland, Jan; Opstad, Trine B; Arnesen, Harald; Andersen, Geir Ø; Seljeflot, Ingebjørg (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
    Background Neutrophil extracellular traps (NETs) have recently been identified as mediators in atherothrombosis. Although NETosis in general has been suggested to be glucose dependent, the transferability ...
  • Grinde, Maria T; Hilmarsdottir, Bylgja; Tunset, Hanna M; Henriksen, Ida M; Kim, Jana; Haugen, Mads H; Rye, Morten B; Mælandsmo, Gunhild M; Moestue, Siver A (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
    Introduction Glutaminase inhibitors target cancer cells by blocking the conversion of glutamine to glutamate, thereby potentially interfering with anaplerosis and synthesis of amino acids and glutathione. ...