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Now showing items 1-10 of 28
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)
Social dysfunction is common in patients with psychotic disorders. Oxytocin is a neuropeptide with a central role in social behavior. This study aims to explore the relationship between oxytocin pathway genes and symptoms ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)
Epidemiological studies suggest a relationship between blood lipids and immune-mediated diseases, but the nature of these associations is not well understood. We used genome-wide association studies (GWAS) to investigate ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)
Converging evidence implicates immune abnormalities in schizophrenia (SCZ), and recent genome-wide association studies (GWAS) have identified immune-related single-nucleotide polymorphisms (SNPs) associated with SCZ. Using ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)
Background: The genotype information carried by Genome-wide association studies (GWAS) seems to have the potential to explain more of the ‘missing heritability’ of complex human phenotypes, given improved statistical ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)
The Enhancing NeuroImaging Genetics through Meta-Analysis (ENIGMA) Consortium is a collaborative network of researchers working together on a range of large-scale studies that integrate data from 70 institutions worldwide. ...
(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2014)
Schizophrenia is a highly heritable disorder. Genetic risk is conferred by a large number of alleles, including common alleles of small effect that might be detected by genome-wide association studies. Here we report a ...
(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2014)
Epidemiological and genetic data support the notion that schizophrenia and bipolar disorder share genetic risk factors. In our previous genome-wide association study, meta-analysis and follow-up (totaling as many as 18 206 ...
(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2014)
It has long been recognized that generalized deficits in cognitive ability represent a core component of schizophrenia (SCZ), evident before full illness onset and independent of medication. The possibility of genetic ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)
Background The present study investigated associations between the strongest joint genetic risk variants for bipolar disorder (BD) and schizophrenia (SCZ) and a history of suicide attempt in patients with BD, SCZ and related ...
(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2014)
Blood pressure is a critical determinant of cardiovascular morbidity and mortality. It is affected by environmental factors, but has a strong heritable component. Despite recent large genome-wide association studies, few ...