In liver disease, irregular proliferation of hepatocytes is an important factor favoring hepatocarcinogenesis. The aim of this cell biological thesis has been to study the impact of epidermal growth factor (EGF) and cellular ...

Cand.med Jo Kramer-Johansen (f.1969) has studied how quality of CPR can be measured and modified by automated feedback during out of hospital cardiac arrest. The results from 284 episodes of cardiac arrest treated in the ...

Sepsis is a systemic inflammatory response syndrome caused by infection. The morbidity and mortality in sepsis is high despite of modern treatment with broad-spectrum antibiotics and supportive therapy. This fact reflects ...

Modern reperfusion strategies and medical treatment reduce myocardial necrosis and have improved prognosis after acute myocardial infarction. However, some patients still develop extensive myocardial infarctions and are ...

Background Several studies have shown that general practitioners (GPs) under-diagnose common mental disorders, and that training courses hardly improve this practice. The influence of GPs' self-perceived ...

Increased incidence and survival of cancer has yielded a large group of cancer survivors. Future fertility and reproduction, including obstetric and perinatal outcome, are some of the main points of concern for individuals ...

Background The MYC oncogene contributes to induction and growth of many cancers but the full spectrum of the MYC transcriptional response remains unclear. Methodology/Principal Findings Using microarrays, we conducted a ...

The prevalence of congestive heart failure (CHF) is increasing dramatically world-wide. Sustained myocardial hypertrophy is an important risk factor for developing CHF, but the underlying mechanisms initiating and maintaining ...

Autophagy is a process used by eukaryotic cells to degrade their own cytoplasm under conditions of nitrogen starvation or stress, in order to obtain amino acids and other small molecules needed for the maintenance of ...

Elevated intracranial pressure (ICP) and reduced cerebral perfusion pressure (CPP) can be life threatening for patients suffering from acute subarachnoid haemorrhage (SAH). Osmotherapy can be used in these situations. Three ...