Cardiac contractility is largely regulated through transients in intracellular Ca2+ concentration ([Ca2+]i). [Ca2+]i is under the influence of the sarcolemmal Na+/Ca2+-exchanger, which is regulated by the intracellular Na+ ...

The main aim of the present thesis was to identify possible shortcomings in diagnostics and treatment in order to improve the outcome for ovarian cancer patients. Especially, the implications of referral practices were ...

Thrombophilia can be defined as an increased, persistent tendency to venous thrombosis. It can be acquired or inherited. The annual incidence of venous thrombosis is about 1 per 1000 in the adult population. Inherited ...

In the case of most diseases drug therapy will enhance health-related quality of life. However, inappropriate use of drugs may be harmful and could evoke new adverse symptoms. This has been known for centuries but, it was ...

Initiation of DNA replication in the bacterium Escherichia coli (E. coli) occurs once per cell cycle at a unique origin site named oriC. The initiator, DnaA, is essential for initiation from oriC. Two control systems have ...

For colorectal cancer surgery is the main and most efficient treatment. In spite of this many patients later suffer from metastases or tumour recurrence. One cause may be peritoneal dissemination of free cancer cells ...

Cand.med Jo Kramer-Johansen (f.1969) has studied how quality of CPR can be measured and modified by automated feedback during out of hospital cardiac arrest. The results from 284 episodes of cardiac arrest treated in the ...

In liver disease, irregular proliferation of hepatocytes is an important factor favoring hepatocarcinogenesis. The aim of this cell biological thesis has been to study the impact of epidermal growth factor (EGF) and cellular ...